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BACKGROUND: An increasing number of Epilepsy Monitoring Units (EMU) display various practices and safety protocols. EMU settings should meet clear, standardized safety protocols to avoid seizure adverse events (SAE). We aim to provide the foundational framework facilitating the establishment of unified evidence-based safety regulations to address the practices and safety measures implemented within the Gulf Cooperation Council (GCC). METHODS: In this cross-sectional study, EMU directors in the GCC were contacted directly by phone to personally complete an electronic 37-item questionnaire sent via text messages and email. From January 2021-December 2021. RESULTS: Seventeen EMUs from six GCC countries participated in the study. All EMU directors responded to the study. Twelve (70.6%) EMUs monitored adults and children, five (29.4%) monitored adults, and none monitored children only. The number of certified epileptologists in the EMUs ranged from one to eight per unit. Fifteen (88.2%) EMUs applied a continuous observation pattern, whereas two (11.8%) performed daytime only. The precautions most commonly used in the video Electroencephalogram (EEG) were seizure pads and bedside oxygen in 15 EMUs (88.2%). For invasive EEG, seizure pads were used in 9 EMUs (52.9%), %) and IV access in 8 EMUs (47.1%). The occurrence of adverse events varied among EMUs. The most common conditions were postictal psychosis 10 (58.8%), injuries 7 (41.2%), and status epilepticus 6 (35.3%). Falls were mainly related to missed seizures or delayed recognition by video monitors in 8 EMUs (47.1%). The extended EMU stay was because of an insufficient number of recorded seizures in 16 EMUs (94.1%), poor seizure lateralization and localization in 10 (58.8%), and re-introduction of AEDs in nine (52.9%). All EMUs had written acute seizure and status epilepticus management protocols. A postictal psychosis management protocol was available for 10 (58.8%). Medications were withdrawn before admission in 6 EMUs (35.3%). The specific medication withdrawal speed protocol upon admission was available in 7 EMUs (41.2%). Pre-admission withdrawal of medication demonstrated a shorter length of stay in both video and invasive EEG, which was statistically significant (ρ (15) = -.529, p =.029; ρ (7) = -.694, p =.038; respectively). CONCLUSION: The practice and safety regulations of EMUs in the GCC vary widely. Each EMU reported the occurrences of SAE and injuries. Precautions, protective measures, and management protocols must be reassessed to minimize the number of SAEs and increase the safety of the EMU.
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Epilepsia , Humanos , Estudos Transversais , Epilepsia/epidemiologia , Eletroencefalografia/métodos , Oriente Médio/epidemiologia , Monitorização Fisiológica/métodos , Inquéritos e Questionários , Adulto , Convulsões/epidemiologia , Anticonvulsivantes/uso terapêutico , Criança , Masculino , FemininoRESUMO
BACKGROUND: Epilepsy frequently accompanies Major Depressive Disorder (MDD). Notably, people with temporal lobe epilepsy and hippocampal sclerosis may face an increased susceptibility to MDD, as evidence indicates the involvement of the limbic system in the development of emotional symptoms. OBJECTIVES: To determine the prevalence and predictors of depression in temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) and compare them to those of other epilepsy types. METHODS: A sample of 293 epilepsy patients, including 159 non-TLE-HS and 134 TLE-HS, were recruited from three hospitals. Of these, 215 completed a two-section electronic survey. The first section collected demographic and epilepsy data, while the second used the Arabic version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E). RESULTS: Of 215 patients, 104 (48%) had TLE-HS-38 with right TLE-HS (37%), 56 with left TLE-HS (54%), and 10 with bilateral TLE-HS (10%). The prevalence and severity of depression was assessed with an NDDI-E score of 15 or higher identified 35 patients (16%) with MDD. Valproic acid and lamotrigine were associated with higher NDDI-E scores. No such associations were found for levetiracetam or carbamazepine. Polytherapy in TLE-HS showed a significant correlation with daily poor concentration. CONCLUSION: We explored the differences in depression prevalence between TLE-HS and other epilepsy types and concluded they are minimal but slightly higher in TLE-HS. Predictors of depression such as seizure frequency and disease duration influenced MDD prevalence in TLE-HS. Lamotrigine and valproate were linked to higher NDDI-E scores.
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Depressão , Epilepsia do Lobo Temporal , Esclerose Hipocampal , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Anticonvulsivantes/uso terapêutico , Estudos Transversais , Depressão/etiologia , Epilepsia do Lobo Temporal/complicações , Epilepsia do Lobo Temporal/psicologia , Esclerose Hipocampal/complicações , Prevalência , Escalas de Graduação Psiquiátrica , Fatores de Risco , IdosoRESUMO
Objectives The objectives of this study were to measure the prevalence of social anxiety disorder and its association with quality of life (QoL) in patients with epilepsy (PWE) in King Khalid University Hospital, Riyadh City, Saudi Arabia. Methodology A self-administrated, online, questionnaire-based, cross-sectional study was conducted at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia on PWE 18 years of age and above from February 2021 to January 2022. Social anxiety and the five domains of QoL were measured using the validated Arabic versions of the Liebowitz social anxiety scale and European quality-of-life 5-dimensions 3-levels (EQ-5D-3L), respectively. Information was collected on sociodemographic characteristics, social support, and adverse life events. Results This study included 246 patients, of which approximately 25% and 15% had mild/moderate and severe/very severe levels of social anxiety, respectively. Severe social anxiety was significantly associated with poor QoL domains, namely, restricted mobility (2.65 [1.00, 6.99]), inability to perform usual activities (3.88 [1.61, 9.36]), pain or discomfort (3.21 [1.38, 7.48]), and anxiety and depression (5.77 [2.45, 13.61]). Similarly, the lack of social support was also significantly associated with poor QoL, such as restricted mobility (2.42 [1.12, 5.22]), restricted self-care (3.64 [1.18, 11.17]), inability to perform usual activities (2.86 [1.42, 5.75]), pain/discomfort (2.53 [1.38, 4.66]), and anxiety and depression (1.93 [1.04, 3.57]). Females showed higher odds for restricted mobility (2.79 [1.29, 6.03]) and low education with limited self-care (7.38 [1.49, 36.71]). Conclusion Patients with epilepsy reported high levels of social anxiety that have a negative effect on their QoL. Healthcare providers should be able to provide counseling to the patient and their family members. In addition, social support is important to improve their mobility and socialization with friends and neighbors.
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OBJECTIVES: To identify the magnitude of treatment adherence among people with epilepsy (PWE) and the impact of sociodemographic, medical and psychosocial factors on treatment adherence. METHODS: A quantitative cross-sectional observational study was performed based on data collected from adult patients attending the epilepsy clinic, King Saud University Medical City, Riyadh, Saudi Arabia. Patients completed paper-based questionnaires including a sociodemographic, cultural, psychiatric history and medical history sections. In addition to that we evaluated treatment adherence by visual-analogue scale (VAS), depressive symptoms by PHQ-9, anxiety symptoms by GAD7, physical symptoms by PHQ-15, attachment style by ECR16 and cognitive impairment by MOCA. RESULTS: A total of 207 patients participated, with a mean age of 34 years;.53.6% were female. The mean patient-reported adherence to their treatment regimen was 81.6%±18.4%. Univariate analysis revealed statistically significant negative associations between depression, anxiety and physical symptoms and treatment adherence. However, multiple linear regression analysis only showed physical symptoms to be a significant predictor for epilepsy medication adherence. CONCLUSION: Somatic (physical) complaints could be important predictors of treatment adherence in (PWE). This study is one of the first to suggest the importance of targeting physical symptoms in screening and intervention approaches to improve Antiepileptic drugs (AEDs) adherence.
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Epilepsia , Adulto , Estudos Transversais , Epilepsia/tratamento farmacológico , Epilepsia/epidemiologia , Epilepsia/psicologia , Feminino , Humanos , Masculino , Adesão à Medicação/psicologia , Prevalência , Arábia Saudita/epidemiologia , Centros de Atenção TerciáriaRESUMO
OBJECTIVE: Understanding the elevations in body temperature after a seizure helps detect etiologies and monitor for complications. We aim to determine the proportion of patients who develop elevated temperatures after a seizure and to examine the trend in temperature change over time. We also seek to examine the effects that an infection or impaired ambulatory status might have on body temperature course, as well as the effect of elevated temperature on the length of hospital stay. METHODS: A retrospective chart review was conducted at King Saud University Medical City. The included patients were individuals older than 12 years of age who presented to the emergency department with seizures between May 2015 and August 2018. Temperature recordings were documented from 18 four-hour time intervals (0-72 h from presentation). Information about age, gender, seizure duration, seizure type, polytherapy, anti-seizure medication, infection, ambulatory status, and length of stay were collected. Logistic regression and a mixed-effects model were used to determine which variables were associated with temperatures of 37.5 °C or higher in the first 12 h of presentation and to estimate the change in temperature over the ensuing time intervals. RESULTS: 416 encounters were identified. The presence of an infection was significantly associated with developing temperature elevation, with an odds ratio (OR) of 2.8 (95% CI [1.54, 5.32]). Ambulatory patients were less likely to have elevations compared to non-ambulatory patients (OR = 0.33; 95% CI [0.18, 0.6]). Temperatures were highest within the first hours of presentation and gradually decreased with each interval by 0.03 °C (p < 0.0001), which increased to 0.12 °C (p = 0.005) if a patient was ambulatory. Temperatures substantially increased across the intervals in patients with infections by 0.21 °C (p < 0.0001). Elevated temperatures were significantly associated with longer hospital stays (p < 0.0001). CONCLUSION: Elevated temperatures can occur after seizures in general, and subside over the ensuing 72 h in the absence of an infection. Physicians should still conduct thorough evaluations in patients with temperatures of 37.5 °C or higher to rule out an underlying infection. The absence of an elevated temperature is favorable and associated with a shorter hospital stay.
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Serviço Hospitalar de Emergência , Convulsões , Febre/etiologia , Humanos , Estudos Retrospectivos , Convulsões/complicações , Convulsões/diagnóstico , TemperaturaRESUMO
This study was carried out to determine the risk of new ischemic events, demonstrated by diffusion weighted magnetic resonance imaging (DW-MRI) in patients undergoing diagnostic conventional cerebral angiogram. MEDLINE, EMBASE, Current Contents, Cochrane Central, Expert Files, and bibliographies of included articles were systematically searched to identify prospective studies that reported MRI findings after diagnostic angiogram. Eligibility criteria included the following elements: manuscripts published between 1999 and 2019; prospective design; only diagnostic angiogram imaging performed prior to the MRI; DW-MRI done before and after the angiogram procedure; and number of new diffusion weighted lesions documented after each procedure. Six studies met the eligibility criteria. The total number of diagnostic angiograms reported was 430. DWI lesions were associated with diagnostic angiograms in 106 (24.65%) of total procedures. Mean time fluoroscopy, procedure by resident operator, and vascular risk factors were the recognised independent risk factors for silent cerebral ischemia after diagnostic angiogram. Key Words: Stroke, Diffusion magnetic resonance imaging, Cerebral infarction, Angiography, Brain ischemia.
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Isquemia Encefálica , Imagem de Difusão por Ressonância Magnética , Isquemia Encefálica/diagnóstico por imagem , Isquemia Encefálica/epidemiologia , Isquemia Encefálica/etiologia , Angiografia Cerebral , Infarto Cerebral/diagnóstico por imagem , Infarto Cerebral/epidemiologia , Infarto Cerebral/etiologia , Humanos , Incidência , Estudos ProspectivosRESUMO
INTRODUCTION: Currently, there are standard and basic versions of the MoCA, the latter designed for those with lower educational achievements. Community-based normative data on these versions of the MoCA from Arabic populations are deficient, and there is little data demonstrating how both scales perform in comparison. We aim to obtain normative performances from both versions and equate the measures of both scales. METHODS: Community-based recruitment of healthy volunteers ≥ 18 years of age. Participants underwent testing with both versions. Demographic data was collected with regard to age, gender, years of education, diabetes, and hypertension. Regression analysis was performed to determine significance of variables, and the circle-arc equating method was used to equate the two scores from each scale. RESULTS: 311 participants were included in the study. The mean (sd) age was 45.8 (15.96), females were 184 (59.16%), and the duration of education was 12.7 (5.67) years. The mean scores on the MoCA-A and MoCA-B were 21.47 (4.53) and 24.37 (4.71) (P < 0.0001), respectively. Multivariate regression showed significance of age and years of education in both versions (both variables with P < 0.0001). Correlation coefficient between the two scales was 0.77 (P < 0.0001). The largest equated difference between both MoCA versions was four points in those scoring from 10-20 on the MoCA-A. CONCLUSION: We present normative data from a large Saudi Arabian community-based sample with two different MoCA tests, and an equating graph is presented to determine the corresponding expected performance between the two scales.
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Disfunção Cognitiva , Vida Independente , Criança , Escolaridade , Feminino , Humanos , Testes de Estado Mental e Demência , Testes Neuropsicológicos , Arábia SauditaRESUMO
INTRODUCTION: This study's purpose is to describe the performance of healthy community dwelling Saudi Arabians on fluency tasks and explore the effects of age, sex and education. METHODS: Arabic-speaking Saudi Arabians > 18 were chosen through convenience sampling. Included were healthy community members whose first language is Arabic. Excluded were anyone with a past history of psychiatric or central neurological diseases, or who was taking medications that affect the central nervous system. Information regarding the variables sex, age, and education was collected. Participants were required to name as many words as they could that started with the letters Ain (ع), Sheen (Ø´), and Qaf (Ù) (letter task), and words that belonged to the categories "countries," "boy names," "girl names," and "four-legged animals" (categorical task). Mean scores were derived for the three letters (ASQ) and four categories (TC). Descriptive statistics, percentile curves, and quantile regressions (0.05, 0.25, 0.5, 0.75, and 0.95) were conducted to determine performance range. RESULTS: The study included 301 participants, comprising 162 (53.47%) females. The M(SD) for age was 46.74 (16) and for years of education 14 (4.78). The M(SD) for ASQ was 26.26 (10.01), and for TC, 81.56 (20.77). Percentile curves demonstrated an initial increase, followed by a decrease, in performance with increasing age on letter and categorical fluency tasks. Performance scores showed an increase of 1 to 1.5 and 2 to 3.5 words in the letter and categorical tasks, respectively, for each additional year of education across the quantiles (both with p < 0.0001). Males scored higher in the 0.05 and 0.95 quantiles of the letter fluency task only. CONCLUSION: We demonstrated a range of normative performance from a Saudi Arabian community, with varying age and education levels. The assessment demonstrated the importance of education as a major variable linearly associated with performance, influencing both tasks.
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Idioma , Comportamento Verbal , Animais , Escolaridade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Testes Neuropsicológicos , Arábia Saudita , Comportamento Verbal/fisiologiaRESUMO
The objective of this study was to administer line bisection (LB) and symbol cancellation (SC) tasks on a sample of healthy Arabs in Saudi Arabia, to determine if normative performance would differ from that of the Western population. A total of 136 healthy individuals were enrolled. Deviation direction from the veridical center and percentage deviation scores (PDS) were determined for LB. The overall performance on SC was calculated. Differences according to gender, education and age were measured. Out of the 2,287 times lines were bisected, 1025 (44.82%) deviated rightward (p < 0.0001). Mean (SD) PDS showed a rightward bias 1.57(3.4), (p < 0.0001). Rightward deviation odds modestly increased with age (OR 1.04, P 0.038). In SC, 63% started searching from the left and 67.5% used a horizontal strategy. The mean (SD) performance score was 0.468 (0.248) with no significant cancellation asymmetry. Female gender, education, and age significantly associated with performance. No correlation was found between the two tasks (p = 0.09). Line bisection error biases in Arabs are opposite of Western biases. Scanning for symbols started on the left side; however, this was smaller than that seen in existing Western reports. Normative performances are different from Western studies, but similarly influenced by the same demographic variables.
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Árabes , Transtornos da Percepção , Atenção , Feminino , Lateralidade Funcional , Humanos , Testes NeuropsicológicosRESUMO
Understanding seizure semiology is one of the most important and crucial steps in diagnosing a seizure disorder. Insular epilepsy may mimic other focal seizure semiologies, leading to misdiagnosis and failed epilepsy surgery. Insular seizures may begin as brief ictal symptoms, such as laryngeal discomfort and unpleasant throat sensations, and spread rapidly to the temporal or frontal regions, causing prominent ictal symptoms different to the initial insular ictal manifestation. Moreover, insular seizures are associated with complex epileptogenic networks and multiple connections. For this reason, accurate seizure semiology helps to lateralize and localize the seizure onset. The insular cortex is deep, and thus scalp electroencephalography is not always beneficial as the epileptic discharges will not be easily recorded, or they will be seen over other cortical regions like the temporal or frontal areas. Insular surgical resection is generally safe, but it requires extensive presurgical workup and surgical precautions in order to minimize mortality.
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Córtex Cerebral , Epilepsia , Humanos , Neurologistas , ConvulsõesRESUMO
OBJECTIVE: To investigate the levels of knowledge and attitudes toward epilepsy surgery among neurologists in Saudi Arabia and evaluate the factors that affect the physicians` knowledge and attitudes. METHODS: A quantitative observational cross-sectional study conducted at King Saud University Medical City, Riyadh. The data were collected using a newly developed, self-administered online questionnaire. The questionnaire contained 3 sections: demographic information, knowledge, and attitudes which then sent to neurologist in Saudi Arabia from December 2016 to March 2017. RESULTS: A total of 106 neurologists met our inclusion criteria. Eighty percent of the participants had at least one epilepsy center in their city, and 78% indicated that they had access to adequate expertise and resources to enable the appropriate selection of epilepsy surgical candidates. Only 57.5% of the neurologists had a sufficient level of knowledge regarding epilepsy surgery. Neurologists with higher level of knowledge referred more patients to EMU and discussed epilepsy surgery more often with their patients. Overall, more than half of the neurologists (52.8%) had a positive attitude toward epilepsy surgery. There was a significantly positive correlation between the scores of knowledge and attitude (p less than 0.001). CONCLUSION: Neurologists in Saudi Arabia appear to have moderate knowledge of and positive attitudes toward epilepsy surgery. The place of the last neurology certificate, type of practicing hospital, and access to expertise and resources, affected their knowledge. Adequate knowledge was positively correlated with attitude.
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Atitude do Pessoal de Saúde , Epilepsia/cirurgia , Conhecimentos, Atitudes e Prática em Saúde , Neurologistas/psicologia , Neurologistas/normas , Inquéritos e Questionários , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Epilepsia/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Arábia Saudita/epidemiologia , Adulto JovemAssuntos
Hidrocortisona/efeitos adversos , Pseudotumor Cerebral/induzido quimicamente , Psoríase/tratamento farmacológico , Acetazolamida/uso terapêutico , Adulto , Anti-Inflamatórios/efeitos adversos , Anticonvulsivantes/uso terapêutico , Humanos , Masculino , Prognóstico , Pseudotumor Cerebral/tratamento farmacológico , Pseudotumor Cerebral/patologia , Adulto JovemRESUMO
BACKGROUND: Little is known of how accurately a first-time seizure witness can provide reliable details of a semiology. Our goal was to determine how accurately first-time seizure witnesses could identify key elements of an epileptic event that would aid the clinician in diagnosing a seizure. METHODS: A total of 172 participants over 17 years of age, with a mean (sd) of 33.12 (13.2) years and 49.4% female, composed of two groups of community dwelling volunteers, were shown two different seizure videos; one with a focal seizure that generalized (GSV), and the other with a partial seizure that did not generalize (PSV). Participants were first asked about what they thought was the event that had occurred. They then went through a history-taking scenario by an assessor using a battery of pre-determined questions about involvement of major regions: the head, eyes, mouth, upper limbs, lower limbs, or change in consciousness. Further details were then sought about direction of movement in the eyes, upper and lower limbs, the side of limb movements and the type of movements in the upper and lower limbs. Analysis was with descriptive statistics and logistic regression. RESULTS: One hundred twenty-two (71.4%) identified the events as seizure or epilepsy. The accuracy of identifying major areas of involvement ranged from 60 to 89.5%. Horizontal head movements were significantly more recognized in the PSV, while involvement of the eyes, lateralization of arm movement, type of left arm movement, leg involvement, and lateralization of leg movement were significantly more recognized in the GSV. Those shown the GSV were more likely to recognize the event as "seizure" or "epilepsy" than those shown the PSV; 78 (84.8%) vs 44 (55.7%), (OR 0.22, p < 0.0001). Younger age was also associated with correct recognition (OR 0.96, P 0.049). False positive responses ranged from 2.5 to 32.5%. CONCLUSION: First-time witnesses can identify important elements more than by chance alone, and are more likely to associate generalized semiologies with seizures or epilepsy than partial semiologies. However, clinicians still need to navigate the witness's account carefully for additional information since routine questioning could result in a misleading false positive answer.
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Voluntários Saudáveis/psicologia , Rememoração Mental , Convulsões/diagnóstico , Adulto , Feminino , Humanos , Masculino , Gravação de Videoteipe , Adulto JovemRESUMO
OBJECTIVE: Graphesthesia is the ability to identify a symbol traced on the skin. Agraphesthesia is the impairment in this ability and is encountered in various disorders of the somatosensory pathways. We aimed to describe the demographic and symbolic features that influence correct recognition of Arabic graphesthesia stimuli in healthy Arabic individuals. METHODS: Participants were community dwelling healthy Arabian individuals of 18 years of age or older. Demographic information collected included age, gender, years of education, and hand dominance. Assessment was conducted using a list of 15 symbols drawn in a single stroke while the hands were obscured from vision. Symbols were current letters and numbers from Arabic script. Each participant was exposed to 60 attempts in total in a random order and correct responses were counted. RESULTS: A total of 126 male and female participants were included. On average, men scored less than women (p < 0.0001), older subjects scored less than those below 30 years of age (p = 0.03), and higher years of education resulted in higher scores (p = 0.047) while handedness did not significantly associate with performance. More correct responses were seen for numerical symbols than letters (p < 0.0001). Symbols with unique script were more likely to be correctly identified. CONCLUSIONS: Number and letter symbols traced on the palm are identified with varying levels of accuracy when conducted according to our method. Female gender, younger age, and higher education are associated with higher scores. Among the many potential symbolic properties that contribute to recognition, a numeric symbol with a unique script is most likely to be correctly identified.
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Percepção do Tato/fisiologia , Adulto , Escolaridade , Feminino , Humanos , Masculino , Caracteres SexuaisRESUMO
OBJECTIVE: To descriptively assess Epilepsy Monitoring Units (EMUs) and the provided services in Saudi Arabia and compare them based on the geographic region. METHODS: In this cross-sectional study, an electronic questionnaire was emailed to all directors of EMUs in Saudi Arabia from July 2013 to January 2016, with constant updates being made by all respondents throughout the period of data collection. RESULTS: All EMU directors participated. There were 11 EMUs in KSA operating in 8 hospitals; 8 (54.5%) EMUs in Riyadh, 2 (18.2%) in Dammam, 2 (18.2%) in Makkah and 1 (9.1%) in Jeddah. Five (54.5%) EMUs were shared for adults and pediatrics, 3 (27.3%) were devoted to adult patients, and 3 (27.3%) to pediatric patients. The average waiting time was 11 weeks (range: 2-52 weeks). The mean percentage of patients coming from an outside region was 30.6%. The average length of stay was 7 days. Less than 100 patients were monitored annually in 54.5% of the EMUs. Seven EMUs (63.6%) admitted less than 100 patients for seizure characterization. Intracranial monitoring was available in all EMUs. Most EMUs (54.5%) admitted less than 100 patients for pre-surgical workup while 36.4% admitted 100-199, and 9.1% admitted more than 300 patients per year. Epilepsy surgeries were performed for less than 50 patients annually in 81.8% of the hospitals. CONCLUSION: There are 11 EMUs in Saudi Arabia fully equipped to serve epileptic patients. However, they are underutilized considering the number of admitted patient and the number of epilepsy surgeries per year. Also, they are unequally distributed throughout the kingdom.
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Epilepsia/diagnóstico , Utilização de Instalações e Serviços/estatística & dados numéricos , Monitorização Neurofisiológica/estatística & dados numéricos , Eletroencefalografia/estatística & dados numéricos , Utilização de Instalações e Serviços/normas , Humanos , Neuroimagem/estatística & dados numéricos , Monitorização Neurofisiológica/métodos , Monitorização Neurofisiológica/normas , Arábia SauditaRESUMO
Weight loss has substantial health benefits, but it is not risk-free. Various neurological disorders have been reported following bariatric surgery-induced weight loss. Here, we report 3 patients who developed multiple sclerosis (MS), one of whom also developed myasthenia gravis (MG), shortly after significant weight loss. Two patients lost weight by following a diet plan and one underwent bariatric surgery. There may be an association between significant weight loss and the development of an autoimmune neurological disorder such as MS or MG; a high index of suspicion is required.
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Esclerose Múltipla/etiologia , Miastenia Gravis/etiologia , Complicações Pós-Operatórias/etiologia , Redução de Peso , Adolescente , Adulto , Cirurgia Bariátrica/efeitos adversos , Restrição Calórica/efeitos adversos , Humanos , Masculino , Esclerose Múltipla/patologia , Miastenia Gravis/patologia , Complicações Pós-Operatórias/patologiaRESUMO
Only a small fraction of patients with acute ischemic stroke receive intravenous thrombolysis (IVT). We sought to assess barriers and practice patterns in using IVT for acute ischemic stroke among neurologists in Saudi Arabia. An electronic survey was sent to all neurologists registered with the Saudi Commission for Health Specialties. A total of 148 (77.5%) neurologists responded. The most common reported barriers for IVT administration were delayed presentation to hospitals (82.4%) and unclear time of symptom onset (50.0%). Only 9.9% of neurologists reported strict adherence to the American Heart Association/American Stroke Association guidelines for IVT administration. The most frequently waived criteria were "minor stroke with National Institutes of Health Stroke Scale [NIHSS] < 5" (49.4%) and "seizure at onset" (45.7%). For the extended 3-4.5-hour window, 18.5% of neurologists reported strict adherence to the four exclusion criteria. The most frequently waived criteria were "age older than 80 years" (53.1%) and "history of both diabetes and prior stroke" (42.0%). In conclusion, most neurologists do not adhere to the IVT exclusion criteria. However, little consensus exists regarding which criteria do not interfere with IVT administration. Barriers to IVT administration were identified and require immediate action by healthcare authorities in Saudi Arabia.
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INTRODUCTION: This study was undertaken to describe a method for quantifying vibration when using a conventional tuning fork (CTF) in comparison to a Rydel-Seiffer tuning fork (RSTF) and to provide reference values. METHODS: Vibration thresholds at index finger and big toe were obtained in 281 participants. Spearman's correlations were performed. Age, weight, and height were analyzed for their covariate effects on vibration threshold. Reference values at the fifth percentile were obtained by quantile regression. RESULTS: The correlation coefficients between CTF and RSTF values at finger/toe were 0.59/0.64 (P = 0.001 for both). Among covariates, only age had a significant effect on vibration threshold. Reference values for CTF at finger/toe for the age groups 20-39 and 40-60 years were 7.4/4.9 and 5.8/4.6 s, respectively. Reference values for RSTF at finger/toe for the age groups 20-39 and 40-60 years were 6.9/5.5 and 6.2/4.7, respectively. DISCUSSION: CTF provides quantitative values that are as good as those provided by RSTF. Age-stratified reference data are provided. Muscle Nerve 57: 49-53, 2018.
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Exame Neurológico/instrumentação , Limiar Sensorial/fisiologia , Vibração , Adulto , Fatores Etários , Estatura/fisiologia , Peso Corporal/fisiologia , Feminino , Dedos/inervação , Dedos/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Valores de Referência , Reprodutibilidade dos Testes , Dedos do Pé/inervação , Dedos do Pé/fisiologia , Adulto JovemRESUMO
OBJECTIVE: To assess the epilepsy services and identify the challenges in hospitals without epilepsy monitoring units (EMUs). In addition, comparisons between governmental and private sectors, as well as between regions, are to be performed. METHODS: A cross sectional study conducted using an online questionnaire distributed to the secondary and tertiary hospitals without EMUs throughout the Kingdom of Saudi Arabia (KSA). The study was conducted from September 2013 to September 2015 and regular updates from all respondents were constantly made. Items in the questionnaire included the region of the institution, the number of pediatric and adult neurologists and neurosurgeons along with their subspecialties, the number of beds in the Neurology Department, whether they provide educational services and have epilepsy clinics and if they refer patients to an EMU or intend to establish one in the future. RESULTS: Forty-three institutions throughout the Kingdom responded, representing a response rate of 54%. The majority of hospitals (58.1%) had no adult epileptologists. A complete lack of pediatric epileptologists was observed in 72.1% of hospitals. Around 39.5% were utilizing beds from internal medicine. Hospitals with an epilepsy clinic represented 34.9% across all regions and sectors. Hospitals with no intention of establishing an EMU represented 53.5%. Hospitals that did not refer their epileptic patients to an EMU represented 30.2%. CONCLUSION: Epilepsy services in KSA hospitals without EMUs are underdeveloped.
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Epilepsia/terapia , Serviços de Saúde/provisão & distribuição , Unidades Hospitalares/provisão & distribuição , Neurologistas/provisão & distribuição , Neurocirurgiões/provisão & distribuição , Pessoal Técnico de Saúde/provisão & distribuição , Estudos Transversais , Eletroencefalografia , Epilepsia/diagnóstico , Humanos , Pediatras/provisão & distribuição , Arábia Saudita , Centros de Cuidados de Saúde Secundários , Inquéritos e Questionários , Centros de Atenção TerciáriaRESUMO
OBJECTIVE: To assess quantitatively sleep medicine services in Saudi Arabia (KSA) and identify obstacles that face specialists and hospitals and preclude the establishment of this service. METHODS: A self-administered questionnaire was mailed to 53 major governmental and private hospitals in KSA on September 2005. The response rate was 69.8%. Data were coded and analyzed. RESULTS: The survey identified 9 sleep disorders facilities in KSA; 7 were defined as sleep disorders centers and 2 as sleep laboratory using the American Academy of Sleep Medicine definitions. The per capita polysomnography (PSG) rate was 7.1 PSG/year/100,000 population, which was much lower than the reported rates in developed countries. The occupancy rate of sleep facilities was found to be low (45.7%). The most important identified obstacles facing the progress of sleep medicine in KSA were lack of trained sleep technicians, shortage of sleep medicine specialists and the un-availability of fund or designated space for the facility. CONCLUSION: Sleep medicine seems to be underdeveloped in KSA compared to developed countries. Organized efforts are needed to overcome the identified obstacles and challenges facing the progress of sleep medicine in KSA.