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1.
Sci Rep ; 13(1): 11918, 2023 Jul 24.
Artigo em Inglês | MEDLINE | ID: mdl-37488183

RESUMO

We have developed a radioluminescence-based survey meter for use in industries in which there is involvement in naturally occurring radioactive material (NORM), also in support of those needing to detect other weak emitters of radiation. The functionality of the system confronts particular shortcomings of the handheld survey meters that are currently being made use of. The device couples a LYSO:Ce scintillator with a photodetector via a polymer optical fibre waveguide, allowing for "intrinsically safe" inspection within pipework, separators, valves and other such component pieces. The small-diameter optical fibre probe is electrically passive, immune to electromagnetic interference, and chemically inert. The readout circuit is entirely incorporated within a handheld casing housing a silicon photomultiplier (SiPM) detection circuit and a microprocessor circuit connected to an LCD display. A 15 m long flexible PMMA optical fibre waveguide is butt coupled to an ABS plastic probe that retains the LYSO:Ce scintillator. Initial tests have included the use of lab-based mixed gamma-ray sources, measurements being made in concert with a reference conventional GM survey-meter. Characterization, via NORM sources at a decontamination facility, has shown useful sensitivity, covering the dose-rate range 0.10- to 28 µSv h-1 (R-squared 0.966), extending to 80 µSv/h as demonstrated in use of a Cs-137 source. The system is shown to provide an effective tool for detection of radioactivity within hard to access locations, in particular for sources emitting at low radiation levels, down to values that approach background.

2.
Appl Radiat Isot ; 194: 110624, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36774822

RESUMO

The goal of the current research was to define the impact of individual characteristics on the response of osteoporosis patients to bisphosphonate medication, as well as the influence of gender on changes in the bone mineral density (BMD).The DXA scan was used to assess a group of 647 osteoporosis patients (533 females and 114 males) who visited the St Bartholomew's Hospitals and Royal London osteoporosis clinics. All male subjects received statistically substantial increases in BMD relative to baseline values after two years of therapy. When compared to prior therapy, men's BMD of the lumbar spine (LS) and hip joint (HJ) rose by 0.057 g/cm2 (6.9%, p0.001) and 0.021 g/cm2 (2.48 percent, p0.001), respectively.. Female patients had BMD changes of 0.028 g/cm2 (3.58 percent, p0.001 vs. prior therapy) and -0.006 g/cm2 (-0.78 percent, p0.001 vs. before treatment) in the lumbar spine and hip, respectively. Male patients exhibited a greater increase in BMD than female patients due to ovarian failure and significant oestrogen loss, which speeds up bone resorption by 90% following menopause, according the research findings.


Assuntos
Densidade Óssea , Osteoporose , Humanos , Masculino , Feminino , Densidade Óssea/fisiologia , Absorciometria de Fóton/métodos , Vértebras Lombares , Difosfonatos
3.
Appl Radiat Isot ; 193: 110626, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36640699

RESUMO

Breast cancer is a common malignancy for females (25% of female cancers) and also has low incidence in males. It was estimated that 1% of all breast malignancies occur in males with mortality rate about 20%, with annual increase in incidence. Risk factors include age, family history, exposure to ionizing radiation and high estrogen and low of androgens hormones level. Diagnosis and screening are challenging due to limiting effectiveness of breast cancer screening. Therefore, patients may expose to ionizing radiation that may contribute in breast cancer incidence in males. In literature, limited studies were published regarding radiation exposure for males during mammography. The objective of this research is to quantify patient doses during male mammogram and to estimate the projected radiogenic risk during the procedure. In total, 42 male patients were undergone mammogram for breast cancer diagnosis during two consecutive years. The mean and range of patient age (years) is 45 (23-80). The mean and standard deviation (SD) of the peak tube potential and tube current time product are 28.64 ± 2. and 149 ± 35.1, respectively. The mean, and range of patients' entrance surface air kerma (ESAK, mGy) per single breast procedure was 5.3 (0.47-27.5). Male patient's received comparable radiation dose per mammogram compared to female procedures. With increasing incidence of male breast cancer, proper guidelines are necessary for the mammographic procedure are necessary to reduce unnecessary radiation doses and radiogenic risk.


Assuntos
Neoplasias da Mama , Exposição à Radiação , Humanos , Feminino , Masculino , Doses de Radiação , Mamografia/métodos , Mama/diagnóstico por imagem , Neoplasias da Mama/patologia , Exposição à Radiação/análise
4.
Appl Radiat Isot ; 192: 110610, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36525913

RESUMO

In comparison to adults and paediatric are more sensitive to ionizing radiation exposure. Computed tomography (CT) is now the dominant source of medical radiologic tests for patients, accounting for more than 70% of total doses to the general public. Paediatric CT brain scans (with and without contrast) are routinely performed for a variety of clinical reasons. As a result, this parameter must be calculated in order to determine relative radiation risk. The goal of this study is to assess the radiation risk to children during CT brain diagnostic procedures. Three hundred fifty three child patients' radiation risk doses were assessed over the course of a year. The mean and ranged of the children's radiation doses were 40.6 ± 8.8 (27.8-45.8) CTDIvol (mGy) and 850 ± 230 (568.1-1126.4) DLP (mGy.cm) for the brain with contrast medium. For CT brain without contrast, the patients' doses were 40.9 ± 9.4 (14.27-64.07) CTDIvol (mGy), and 866.1 ± 289.3 (203.6-2484.9) DLP (mGy.cm). The characteristics related to the radiation dose were retrieved from the scan protocol generated by the CT system by the participating physicians after each procedure. Furthermore, optimizing the CT acquisition parameter is critical for increasing the benefit while lowering the procedure's radiogenic risk. The patients' radiation dose is comparable with the most previously published studies and international diagnostic reference levels (DRLs). Radiation dose optimization is recommended due to high sensitivity of the paediatric patients to ionizing radiation.


Assuntos
Angiografia por Tomografia Computadorizada , Tomografia Computadorizada por Raios X , Adulto , Humanos , Criança , Doses de Radiação , Tomografia Computadorizada por Raios X/métodos , Cabeça , Encéfalo/diagnóstico por imagem , Valores de Referência
5.
Appl Radiat Isot ; 193: 110627, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36584412

RESUMO

Computed tomography is widely used for planar imaging. Previous studies showed that CR systems involve higher patient radiation doses compared to digital systems. Therefore, assessing the patient's dose and CR system performance is necessary to ensure that patients received minimal dose with the highest possible image quality. The study was performed at three medical diagnostic centers in Sudan: Medical Corps Hospital (MCH), Advance Diagnostic Center (ADC), and Advance Medical Center (AMC). The following tools were used in this study: Tape measure, Adhesive tape, 1.5 mm copper filtration (>10 × 10 cm), TO 20 threshold contrast test object, Resolution test object (e.g., Huttner 18), MI geometry test object or lead ruler, Contact mish, Piranha (semiconductor detector), Small lead or copper block (∼5 × 5 cm), and Steel ruler, to do a different type of tests (Dark Noise, Erasure cycle efficiency, Sensitivity Index calibration, Sensitivity Index consistency, Uniformity, Scaling errors, Blurring, Limiting spatial Resolution, Threshold, and Laser beam Function. Entrance surface air kerma (ESAK (mGy) was calculated from patient exposure parameters using DosCal software for three imaging modalities. A total of 199 patients were examined (112 chest X rays, 77 lumbar spine). The mean and standard deviation (sd) for patients ESAK (mGy) were 2.56 ± 0.1 mGy and 1.6 mGy for the Anteroposterior (AP) and lateral projections for the lumbar spine, respectively. The mean and sd for the patient's chest doses were 0.1 ± 0.01 for the chest X-ray procedures. The three medical diagnostic centers' CR system performance was evaluated and found that all of the three centers have good CR system functions. All the centers satisfy all the criteria of acceptable visual tests. CR's image quality and sensitivity were evaluated, and the CR image is good because it has good contrast and resolution. All the CR system available in the medical centers and upgraded from old X-ray systems to new systems, has been found to work well. The patient's doses were comparable for the chest X-ray procedures, while patients' doses from the lumbar spine showed variation up to 2 folds due to the variation in patients' weight and X-ray machine setting. Patients dose optimization is recommended to ensure the patients received a minimal dose while obtaining the diagnostic findings.


Assuntos
Cobre , Vértebras Lombares , Humanos , Doses de Radiação , Radiografia , Raios X
6.
Sci Rep ; 11(1): 14557, 2021 07 15.
Artigo em Inglês | MEDLINE | ID: mdl-34267237

RESUMO

Worldwide, thyroid cancer accounts for some 10% of total cancer incidence, most markedly for females. Thyroid cancer radiotherapy, typically using 131I (T1/2 8.02 days; ß- max energy 606 keV, branching ratio 89.9%), is widely adopted as an adjunct to surgery or to treat inoperable cancer and hyperthyroidism. With staff potentially receiving significant doses during source preparation and administration, radiation protection and safety assessment are required in ensuring practice complies with international guidelines. The present study, concerning a total of 206 patient radioiodine therapies carried out at King Faisal Specialist Hospital and Research Center over a 6-month period, seeks to evaluate patient and occupational exposures during hospitalization, measuring ambient doses and estimating radiation risk. Using calibrated survey meters, patient exposure dose-rate estimates were obtained at a distance of 30-, 100- and 300 cm from the neck region of each patient. Occupational and ambient doses were measured using calibrated thermoluminescent dosimeters. The mean and range of administered activity (AA, in MBq) for the thyroid cancer and hyperthyroidism treatment groups were 4244 ± 2021 (1669-8066), 1507.9 ± 324.1 (977.9-1836.9), respectively. The mean annual occupational doses were 1.2 mSv, that for ambient doses outside of the isolation room corridors were found to be 0.2 mSv, while ambient doses at the nursing station were below the lower limit of detection. Exposures to staff from patients being treated for thyroid cancer were less compared to hyperthyroidism patients. With a well-defined protocol, also complying with international safety requirements, occupational exposures were found to be relatively high, greater than most reported in previous studies.


Assuntos
Radioisótopos do Iodo/efeitos adversos , Radioisótopos do Iodo/uso terapêutico , Exposição Ocupacional/análise , Neoplasias da Glândula Tireoide/radioterapia , Adulto , Idoso , Feminino , Pessoal de Saúde , Humanos , Hipertireoidismo/radioterapia , Radioisótopos do Iodo/administração & dosagem , Masculino , Pessoa de Meia-Idade , Exposição Ocupacional/efeitos adversos , Proteção Radiológica , Arábia Saudita , Dosimetria Termoluminescente/métodos , Adulto Jovem
7.
Radiat Prot Dosimetry ; 195(3-4): 314-318, 2021 Oct 12.
Artigo em Inglês | MEDLINE | ID: mdl-34265851

RESUMO

The objective of this study is to estimate the annual effective dose for cardiologists and nurses by measuring Hp(10) and Hp(0.07) during cardiac catheterization procedures. A total of 16 staffs members were working in interventional cardiology during 1 year at a tertiary hospital. The occupational dose was measured using calibrated thermo-luminescent dosemeters (TLD-100, LiF:Mg,Ti). The overall mean and range of the annual Hp(10) and Hp(0.07) (mSv) for cardiologists were 3.7 (0.13-14.5) and 3.2 (0.21-14.7), respectively. Cardiologists were frequently exposed to higher doses compared with nurses and technologists. The exposure showed wide variations, which depend on occupation and workload. Staff is adhered to radiation protection guidelines regarding shielding the trunk, thyroid shield, thus appropriately protected. Lens dose measurement is recommended to ensure that dose limit is not exceeded.


Assuntos
Cristalino , Exposição Ocupacional , Exposição à Radiação , Cateterismo Cardíaco , Humanos , Exposição Ocupacional/análise , Doses de Radiação , Exposição à Radiação/análise , Arábia Saudita
8.
Radiat Prot Dosimetry ; 195(3-4): 349-354, 2021 Oct 12.
Artigo em Inglês | MEDLINE | ID: mdl-34144608

RESUMO

This study has sought to evaluate patient exposures during the course of particular diagnostic positron emission tomography and computed tomography (PET/CT) techniques. A total of 73 patients were examined using two types of radiopharmaceutical: 18F-fluorocholine (FCH, 48 patients) and 68Ga-prostate-specific membrane antigen (PSMA, 25 patients). The mean and range of administered activity (AA) in MBq, and effective dose (mSv) for FCH were 314.4 ± 61.6 (462.5-216.8) and 5.9 ± 1.2 (8.8-4.11), respectively. Quoted in the same set of units, the mean and range of AA and effective dose for 68Ga-PSMA were 179.3 ± 92.3 (603.1-115.1) and 17.9 ± 9.2 (60.3-11.5). Patient effective doses from 18F-FCH being a factor of two greater than the dose resulting from 68Ga-PSMA PET/CT procedures. CT accounts for some 84 and 23% for 18F-FCH and 68Ga-PSMA procedures, accordingly CT acquisition parameter optimization is recommended. Patient doses have been found to be slightly greater than previous studies.


Assuntos
Neoplasias da Próstata , Exposição à Radiação , Colina/análogos & derivados , Isótopos de Gálio , Radioisótopos de Gálio , Humanos , Masculino , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Neoplasias da Próstata/diagnóstico por imagem , Neoplasias da Próstata/radioterapia
9.
Radiat Prot Dosimetry ; 194(2-3): 76-81, 2021 Jul 14.
Artigo em Inglês | MEDLINE | ID: mdl-34047347

RESUMO

The aim of this research paper is to estimate the mean value of extremely low frequency (ELF) exposure in schools in Greece. Detailed ELF measurements were conducted and analyzed by the Weighted Peak Method (WPM), which estimates the overall contribution of electromagnetic waves from 1 Hz to 400 kHz, including their phases. A sample of 243 schools was sampled to calculate. The mean value of ELF magnetic fields (MFs) measured in these two groups comprising 243 schools was the principal focus of interest. ELF MF measurements taken in schools situated both far from and near ELF sources had mean and maximum values well below the current International Commission on Non-Ionizing Radiation Protection (ICNIRP) standard. The mean value of ELF MFs from all sources within the sampled schools in Greece was 0.21 µΤ. A statically significant difference between the mean MFs measured in the two groups of schools was found, but the MFs in both groups were much lower than the ICNIRP standard.


Assuntos
Campos Eletromagnéticos , Exposição Ambiental , Grécia , Campos Magnéticos , Instituições Acadêmicas
10.
Saudi J Biol Sci ; 28(1): 35-39, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33424280

RESUMO

Medical exposure of the general population due to radiological investigations is the foremost source of all artificial ionising radiation. Here, we focus on a particular diagnostic radiological procedure, as only limited data are published with regard to radiation measurements during urethrograpic imaging. Specifically, this work seeks to estimate patient and occupational effective doses during urethrographic procedures at three radiology hospitals. Both staff and patient X-ray exposure levels were calculated in terms of entrance surface air kerma (ESAK), obtained by means of lithium fluoride thermoluminescent dosimeters (TLD-100(LiF:Mg:Cu.P)) for 243 urethrographic examinations. Patient radiation effective doses per procedure were estimated using conversion factors obtained from the use of Public Health England computer software. In units of mGy, the median and range of ESAK per examination were found to be 10.8 (3.6-26.2), 7.0 (0.2-32.3), and 24.3 (9.0-32.0) in Hospitals A, B, and C, respectively. The overall mean and range of staff doses (in µGy) were found to be 310 (4.0-1750) per procedure. With the exception of hospital C, the present evaluations of radiation dose have been found to be similar to those of previously published research. The wide range of patient and staff doses illustrate the need for radiation dose optimisation.

11.
Appl Radiat Isot ; 168: 109520, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33307438

RESUMO

The various technological advancements in computed tomography (CT) have resulted in remarkable growth in the use of CT imaging in clinical practice, not the least of which has been its establishment as the most valuable imaging examination for the assessment of cardiovascular system disorders. The objective of this study was to assess the effective radiation dose and radiation risk for patients during cardiac CT procedures, based on studies from four different hospitals equipped with 128 slice CT equipment. A total of eighty-three patients were investigated in this study with different clinical indications. Effective doses were also calculated using software based on Monte Carlo simulation. The mean patient age (years), weight (kg), and body mass index (BMI (kg/m2)) were 49 ± 11, 82 ± 12, and 31 ± 6, respectively. The results of the study revealed that the tube voltage (kVp) and tube current-exposure time product (mAs) ranged between 100 to 140 and 50 to 840 respectively. The overall average patient dose values for the volume CT dose index [(CTDIvol), in mGy)] and dose length product (DLP) (in mGy·cm) were 34.8 ± 15 (3.7-117.0) and 383.8 ± 354 (46.0-3277.0) respectively. The average effective dose (mSv) was 15.2 ± 8 (1.2-61.8). The radiation dose values showed wide variation between different hospitals and even within the same hospital. The results indicate the need to optimize radiation dose and to establish diagnostic reference levels (DRLs) for patients undergoing coronary computed tomography angiography (CCTA), also to harmonize the imaging protocols to ensure reduced radiation risk.


Assuntos
Angiografia Coronária/métodos , Coração/efeitos da radiação , Tomografia Computadorizada por Raios X/efeitos adversos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doses de Radiação , Adulto Jovem
12.
West Indian med. j ; 69(4): 201-206, 2021. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1515648

RESUMO

ABSTRACT Objective: To measure the Achilles tendon length, thickness and cross-sectional area in asymptomatic adult Saudi participants and to investigate the possible changes in these measurements based on their different ages and body height. Methods: The prospective cohort study was done between January 2014 and March 2015. A total of 200 asymptomatic participants with 175 males (87.5%) and 25 females (12.5%) between the ages of 14 and 65 years, with the mean age of 25 ± 1.5 years, were scanned at two radiology departments. Ultrasound (US) scans for the Achilles tendons were performed using a Hitachi (EZU-MT30-S1 HI Vision Avius, Hitachi, Japan) US machine. Statistical Package for the Social Sciences (SPSS Inc., Chicago, IL, USA) was used to analyse the results. Results: There was no significant difference in the length, cross-sectional area and thickness of the Achilles tendons among the participants of different ages; however, the cross-sectional area of Achilles tendons of the older participants (≥ 47 years) was higher than that of the participants of the younger age groups. Moreover, there was no correlation between the length, cross-sectional area, and thickness of the Achilles tendons and their body heights; however, the participants of ≥ 153 cm in height showed an increase in their Achilles tendon cross-sectional areas. Conclusion: Ultrasound is a useful imaging tool in the assessment of the Achilles tendons. The normal variations of the tendon morphological characteristics should be considered in the clinical diagnosis. Additional studies on the correlations among the Achilles tendon length, thickness and cross-sectional areas of ethnicity of the participants in Saudi Arabia are suggested.

13.
Appl Radiat Isot ; 164: 109240, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32819499

RESUMO

Lutetium-177 (DOTATATE) (177Lu; T1/2 6.7 days), a labelled ß- and Auger-electron emitter, is widely used in treatment of neuroendocrine tumours. During performance of the procedure, staff and other patients can potentially receive significant doses in interception of the gamma emissions [113 keV (6.4%) and 208 keV (11%)] that are associated with the particle decays. While radiation protection and safety assessment are required in seeking to ensure practices comply with international guidelines, only limited published studies are available. The objectives of present study are to evaluate patient and occupational exposures, measuring ambient doses and estimating the radiation risk. The results, obtained from studies carried out in Riyadh over an 11 month period, at King Faisal Specialist Hospital and Research Center, concerned a total of 33 177Lu therapy patients. Patient exposures were estimated using a calibrated Victoreen 451P survey meter (Fluke Biomedical), for separations of 30 cm, 100 cm and 300 cm, also behind a bed shield that was used during hospitalization of the therapy patients. Occupational and ambient doses were also measured through use of calibrated thermoluminescent dosimeters and an automatic TLD reader (Harshaw 6600). The mean and range of administered activity (in MBq)) was 7115.2 ± 917.2 (4329-7955). The ambient dose at corridors outside of therapy isolation rooms was 1.2 mSv over the 11 month period, that at the nursing station was below the limit of detection and annual occupational doses were below the annual dose limit of 20 mSv. Special concern needs to be paid to comforters (carers) and family members during the early stage of radioisotope administration.


Assuntos
Neoplasias Meníngeas/radioterapia , Meningioma/radioterapia , Exposição Ocupacional , Octreotida/análogos & derivados , Compostos Organometálicos/uso terapêutico , Humanos , Medicina Nuclear , Octreotida/administração & dosagem , Octreotida/uso terapêutico , Compostos Organometálicos/administração & dosagem , Medicina de Precisão , Dosagem Radioterapêutica
14.
Radiat Prot Dosimetry ; 189(3): 395-400, 2020 07 17.
Artigo em Inglês | MEDLINE | ID: mdl-32409836

RESUMO

BACKGROUND: There is an exponential growth of public concern worldwide regarding the exposure to electromagnetic fields (EMF) generated by wind turbines. The high concern of the general population enhances the fact that EMF exposure remains a crucial issue that demands specific actions and reliable data to evaluate possible health hazards. MATERIALS AND METHODS: EMF exposure measurements were conducted in two wind farm (W/F) areas in Greece. The magnetic field strength concentrated in the proximity of 22 wind turbines (20 type of Gamesa Eolica Siemens of total power of 17 MW and 2 type of E53 Enercon, 800 KW each). Measurements were conducted using a Narda-NBM-550 basic unit (Narda Safety Test Solutions Company) using EHP-50F probe. The EMF exposure measurements were processed applying the weighted peak method (WPM), according to the 2013/35/EU Directive. WPM provides correction of the measured value of pulse signals, taking into account the phases of the various frequency components. The data were classified under two scenarios of EMF exposure: 'high wind' and 'low wind' conditions. RESULTS: The variation of the magnetic field strength was calculated between 1.13 and 1.42% (WPM). Measurements indicate that the intensity of the emitted magnetic field at the base of the wind turbines, in both high and low wind conditions, was relatively low (mean = 0.146 µT), while decreasing rapidly with increasing distance and reaching background values 6 m from the base. CONCLUSION: The results of the present study indicate that EMF levels are similar or even lower compared to those in urban areas and well below the national and international safety limits.


Assuntos
Campos Eletromagnéticos , Exposição Ambiental , Campos Eletromagnéticos/efeitos adversos , Grécia , Humanos
15.
Saudi J Biol Sci ; 26(6): 1107-1111, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31516336

RESUMO

The aims of the present work were to quantify radiation doses arises from patients' exposure in mammographic X-ray imaging procedures and to estimate the radiation induced cancer risk. Sixty patients were evaluated using a calibrated digital mammography unit at King Khaled Hospital and Prince Sultan Center, Alkharj, Saudi Arabia. The average patient age (years) was 44.4 ±â€¯10 (26-69). The average and range of exposure parameters were 29.1 ±â€¯1.9 (24.0-33.0) and 78.4 ±â€¯17.5 (28.0-173.0) for X-ray tube potential (kVp) and current multiplied by the exposure time (s) (mAs), respectively. The MGD (mGy) per single projection for craniocaudal (CC), Medio lateral oblique (MLO) and lateromedial (LM) was 1.02 ±â€¯0.2 (0.4-1.8), 1.1 ±â€¯0.3 (0.5-1.8), 1.1 ±â€¯0.3 (0.5-1.9) per procedure, in that order. The average cancer risk per projection is 177 per million procedures. The cancer risk is significant during multiple image acquisition. The study revealed that 80% of the procedures with normal findings. However, precise justification is required especially for young patients.

16.
Appl Radiat Isot ; 141: 288-291, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30122471

RESUMO

Patient radiation dose and image quality are primary issues in the conduct of nuclear medicine (NM) procedures. A range of protocols are currently used in image acquisition and analysis of quality control (QC) tests, with National Electrical Manufacturers Association (NEMA) methods and protocols widely accepted in providing an accurate description, measurement and report of γ-camera performance parameters. However, no standard software is available for image analysis. Present study compares vendor QC software analysis and three types of software freely downloadable from the internet: NMQC, NM Toolkit and ImageJ-NM Toolkit software. These were used for image analysis of QC tests of γ-cameras based on NEMA protocols including non-uniformity evaluation. Ten non-uniformity QC images were obtained using a dual head γ-camera installed in Trieste General Hospital and then analyzed. Excel analysis was used as the baseline calculation for the non-uniformity test according to NEMA procedures. The results of non-uniformity analysis showed good agreement between the independent types of software and Excel calculations (the average differences were 0.3%, 2.9%, 1.3% and 1.6% for the Useful Field of View (UFOV) integral, UFOV differential, Central Field of View (CFOV) integral and CFOV differential, respectively), while significant differences were detected following analysis using the company QC software when compared with Excel analysis (the average differences were 14.6%, 20.7%, 25.7% and 31.9% for the UFOV integral, UFOV differential, CFOV integral and CFOV differential, respectively). Compared to use of Excel calculations use of NMQC software was found to be in close accord. Variation in results obtained using the three types of software and γ-camera QC software was due to the use of different pixel sizes. It is important to conduct independent analyses tests in addition to using the vendor QC software in order to determine the differences between values.


Assuntos
Câmaras gama/normas , Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único/normas , Câmaras gama/estatística & dados numéricos , Humanos , Controle de Qualidade , Interpretação de Imagem Radiográfica Assistida por Computador/normas , Interpretação de Imagem Radiográfica Assistida por Computador/estatística & dados numéricos , Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único/instrumentação , Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único/estatística & dados numéricos , Software
17.
Appl Radiat Isot ; 141: 270-274, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30145016

RESUMO

With associated cure rates in excess of 90%, targeted 131I radioactive iodine therapy has clearly improved thyroid cancer survival. Thus said, potential radiation risks to staff represent a particular concern, current study seeking to determine the radiation exposure of staff from 131I patients during hospitalization, also estimating accumulated dose and related risk to staff during preparation of the radioactive iodine. In present study made over the three-month period 1st February to 1st May 2017, a total of 69 patient treatments were investigated (comprising a cohort of 46 females and 23 males), this being a patient treatment load typically reflective of the workload at the particular centre for such treatments. The patients were administered sodium iodide 131I, retained in capsules containing activities ranging from 370 to 5550 MBq at the time of calibration, radioiodine activity depends on many factors such as gender, clinical indication, body mass index and age. The staff radiation dose arising from each patient treatment was measured on three consecutive days subsequent to capsule administration. In units of µSv, the mean and dose-rates range at distances from the patients of 5 cm, 1 m and 2 m were 209 ±â€¯73 (165-294), 6.8 ±â€¯2 (5.3-9.5) and 0.9 ±â€¯0.3 (0.7-1.2). The annual dose (also measured in units of µSv), based on annual records of doses, for medical physicists, technologists and nurses were 604, 680 and 1000 µSv respectively. In regard to current practice and workload, staff exposures were all found to be below the annual dose limit for radiation workers.


Assuntos
Radioisótopos do Iodo/efeitos adversos , Exposição Ocupacional/efeitos adversos , Exposição à Radiação/efeitos adversos , Compostos Radiofarmacêuticos/efeitos adversos , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doses de Radiação , Monitoramento de Radiação/instrumentação , Neoplasias da Glândula Tireoide/radioterapia , Adulto Jovem
18.
Appl Radiat Isot ; 141: 261-265, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30054177

RESUMO

Patient effective doses and the associated radiation risks arising from particular computed tomography (CT) imaging procedures are assessed. The objectives of this research are to measure radiation doses for patients and to quantify the radiogenic risks from CT brain and chest procedures. Patient data were collected from five calibrated CT modality machines in Saudi Arabia. The results are from a study of a total of 60 patients examined during CT procedures using the calibrated CT units. For CT brain and chest, the mean patient effective doses were 1.9 mSv (with a range of 0.6-2.5 mSv) and 7.4 mSv (with a range of 0.5-34.8 mSv) respectively. The radiogenic risk to patients ranged from between 10-5 and 10-4 per procedure. With 65% of the CT procedure cases diagnosed as normal, this prompts re-evaluation of the referral criteria. The establishment of diagnostic reference levels (DRL) and implementation of radiation dose optimisation measures would further help reduce doses to optimal values.


Assuntos
Tomografia Computadorizada por Raios X/efeitos adversos , Tomografia Computadorizada por Raios X/métodos , Adulto , Encéfalo/diagnóstico por imagem , Calibragem , Feminino , Humanos , Masculino , Neoplasias Induzidas por Radiação/etiologia , Neoplasias Induzidas por Radiação/prevenção & controle , Doses de Radiação , Exposição à Radiação/prevenção & controle , Lesões por Radiação/etiologia , Lesões por Radiação/prevenção & controle , Proteção Radiológica , Arábia Saudita , Tórax/diagnóstico por imagem , Tomografia Computadorizada por Raios X/normas
19.
Appl Radiat Isot ; 138: 14-17, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28830729

RESUMO

A pacemaker, which is used for heart resynchronization with electrical impulses, is used to manage many clinical conditions. Recently, the frequency of pacemaker implantation procedures has increased to more than 50% worldwide. During this procedure, patients can be exposed to excessive radiation exposure. Wide range of doses has been reported in previous studies, suggesting that optimization of this procedure has not been fulfilled yet. The current study evaluated patient radiation exposure during cardiac pacemaker procedures and quantified the patient effective dose. A total of 145 procedures were performed for five pacemaker procedures (VVI, VVIR, VVD, VVDR, and DDDR) at two hospitals. Patient doses were measured using the kerma-area product meter. Effective doses were estimated using software based on Monte Carlo simulation from the National Radiological Protection Board (NRPB, now The Health Protection Agency). The effective dose values were used to estimate cancer risk from the pacemaker procedure. Patient demographic data and exposure parameters for fluoroscopy and radiography were quantified. The mean patient doses ± SD per procedure (Gycm2) for VVI, VVIR, VVD, VVDR, and DDDR were 1.52 ± 0.13 (1.43-1.61), 3.28 ± 2.34 (0.29-8.73), 3.04 ± 1.67 (1.57-4.86), 6.04 ± 2.326 3.29-8.58), and 8.8 ± 3.6 (4.5-26.20), respectively. The overall patient effective dose was 1.1mSv per procedure. It is obvious that the DDDR procedure exposed patients to the highest radiation dose. Patient dose variation can be attributed to procedure type, exposure parameter settings, and fluoroscopy time. The results of this study showed that patient doses during different pacemaker procedures are lower compared to previous reported values. Patient risk from pacemaker procedure is low, compared to other cardiac interventional procedures. Patients' exposures were mainly influenced by the type of procedures and the clinical indication.


Assuntos
Fluoroscopia/métodos , Marca-Passo Artificial , Radiografia Intervencionista/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Fluoroscopia/efeitos adversos , Humanos , Masculino , Pessoa de Meia-Idade , Método de Monte Carlo , Neoplasias Induzidas por Radiação/etiologia , Doses de Radiação , Exposição à Radiação/análise , Exposição à Radiação/prevenção & controle , Proteção Radiológica/métodos , Radiografia Intervencionista/efeitos adversos , Radiometria/estatística & dados numéricos , Fatores de Risco
20.
Appl Radiat Isot ; 138: 45-49, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28780202

RESUMO

In the modern clinical practice of diagnostic radiology there is a growing demand for radiation dosimetry, it also being recognized that with increasing use of X-ray examinations additional population dose will result, accompanied by an additional albeit low potential for genetic consequences. At the doses typical of diagnostic radiology there is also a low statistical risk for cancer induction; in adhering to best practice, to be also implied is a low but non-negligible potential for deterministic sensitive organ responses, including in regard to the skin and eyes. Risk reduction is important, in line with the principle of ALARP, both in regard to staff and patients alike; for the latter modern practice is usually guided by Dose Reference Levels (DRL) while for the former and members of the public, legislated controls (supported by safe working practices) pertain. As such, effective, reliable and accurate means of dosimetry are required in support of these actions. Recent studies have shown that Ge-doped-silica glass fibres offer several advantages over the well-established phosphor-based TL dosimeters (TLD), including excellent sensitivity at diagnostic doses as demonstrated herein, low fading, good reproducibility and re-usability, as well as representing a water impervious, robust dosimetric system. In addition, these silica-based fibres show good linearity over a wide dynamic range of dose and dose-rate and are directionally independent. In the present study, we investigate tailor made doped-silica glass thermoluminescence (TL) for applications in medical diagnostic imaging dosimetry. The aim is to develop a dosimeter of sensitivity greater than that of the commonly used LiF (Mg,Ti) phosphor. We examine the ability of such doped glass media to detect the typically low levels of radiation in diagnostic applications (from fractions of a mGy through to several mGy or more), including, mammography and dental radiology, use being made of x-ray tubes located at the Royal Surrey County Hospital. We further examine dose-linearity, energy response and fading.


Assuntos
Germânio , Vidro , Dióxido de Silício , Dosimetria Termoluminescente/métodos , Relação Dose-Resposta à Radiação , Feminino , Humanos , Mamografia , Doses de Radiação , Radiografia , Radiografia Dentária , Padrões de Referência , Dosimetria Termoluminescente/normas , Dosimetria Termoluminescente/estatística & dados numéricos
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