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1.
Eur Rev Med Pharmacol Sci ; 28(1): 23-29, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38235895

RESUMO

OBJECTIVE: This study aims to assess the effects of the most recent remineralizing agents, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), CO2 laser irradiation + topical fluoride (CO2 laser + TF), and Nanosilver fluoride - M. oleifera (NSF-MOLE), on the shear bond strength (SBS) and bond failure between resin composite and remineralized caries affected dentin (CAD). MATERIALS AND METHODS: Fifty human molars with occlusal caries reaching approximately halfway through the dentin were immersed in a 4% thymol solution. The infected dentin was removed using an excavator and the CAD surface was exposed. The sample was allocated into five groups (n=10) based on the remineralizing agent applied. Group 1: no remineralizing agent, group 2: CPP-ACP, group 3: Riva Star, group 4: NSF:MOLE, and group 5: (CO2 laser + TF). The shear bond testing procedure was conducted utilizing a universal testing machine and a stereo-microscope was used to study the failure pattern. The researchers utilized a one-way analysis of variance. The Tukey post hoc test was conducted for multiple comparison tests. RESULTS: Group 4 (NSF-MOLE) (13.77±1.94 MPa) treated testers recognized the highest bond values of tooth color restoration to the CAD surface. Nonetheless, group 1 test samples with no mineralization unveiled the minimum outcome of bond integrity (9.12±1.14 MPa). Intergroup comparison exploration showed that group 2 (CPP-ACP), group 4 (NSF-MOLE) (13.77±1.94 MPa), and group 5 (CO2 laser + TF) established comparable values of SBS. Furthermore, group 3 (Riva Star) displayed better SBS than group 1 but lower than group 2, group 4, and group 5. CONCLUSIONS: Remineralization of CAD using modern regimes (CPP-ACP, NSF-MOLE, and CO2 laser + TF has the potential to be used to enhance the bond strength of CAD to composite restoration.


Assuntos
Fosfatos de Cálcio , Fluoretos , Moringa oleifera , Humanos , Fluoretos/farmacologia , Fosfopeptídeos , Caseínas/farmacologia , Caseínas/química , Resinas Compostas , Suscetibilidade à Cárie Dentária , Dentina , Teste de Materiais
2.
Eur Rev Med Pharmacol Sci ; 27(18): 8350-8359, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37782152

RESUMO

OBJECTIVE: This study aimed to assess the impact of various cavity disinfection methods on the adhesive bond integrity of composite resin to caries-affected dentin (CAD). Additionally, it will evaluate the micro tensile bond strength (µTBS) of different dentin substrates [CAD and sound dentin (SD)] using various adhesive agents. MATERIALS AND METHODS: The sample consisted of twenty human mandibular molars with sound dentin (SD) and eighty with CAD. All samples were positioned in a group of polyvinyl pipes with an internal diameter of 3 mm and were positioned perpendicularly up against the cementoenamel junction (CEJ). A total of 60 CAD samples (n=10) were used for shear bond strength (SBS) testing. CAD samples were disinfected with erbium chromium-doped yttrium, scandium, gallium and garnet (Er, Cr: YSGG) laser in group 1, Diode laser in group 2, neodymium-doped yttrium aluminum garnet (Nd: YAG) laser in group 3, riboflavin in group 4, curcumin in group 5, and chlorhexidine in group 6. Sixty CAD samples were treated with Scotchbond™ Etchant and Scotchbond™ multi-purpose primer and bonded with composite for SBS testing. On the twenty remaining CAD samples that did not undergo any type of disinfection, as well as the twenty samples that had sound dentin (SD), two different types of adhesive systems were used for micro tensile testing. For ten of each CAD and SD sample, 3c™ Adper™ Scotchbond™ multi-purpose adhesive was applied to the dentin surfaces. For the remaining ten CAD and SD samples, the All-Bond 2 adhesive system was used. The samples were prepared for µTBS testing. In all specimens, bond failure was assessed using a stereomicroscope. Analysis of variance (ANOVA) and Tukey Honestly Significant Difference (HSD) tests were used to compare the means of multiple groups, at a significance level of p<0.05. RESULTS: CAD disinfected with chlorhexidine (CHX) (17.19±1.02 MPa) exhibited the highest SBS values. Samples in group 5 disinfected with curcumin activated by photodynamic therapy (PDT) showed the lowest SBS (12.49±1.11 MPa). Scotchbond adhesive displayed comparable µTBS (p>0.05) when applied on CAD and SD. Moreover, All-Bond 2 adhesive, when applied on CAD, exhibited µTBS significantly lower than All-Bond 2 adhesive on SD (p<0.05). Analysis of debonded CAD surface after SBS showed that a cohesive type of failure was dominant in different experimental groups, followed by adhesive CONCLUSIONS: CAD disinfection with Er:Cr: YSGG, Diode Laser, and Riboflavin activated by photodynamic therapy have the potential to be used as an alternative to CHX for acceptable shear bond strength. The use of Adper™ Scotchbond™ multi-purpose adhesive on CAD and SD did not significantly compromise µTBS.


Assuntos
Curcumina , Fármacos Fotossensibilizantes , Humanos , Lasers Semicondutores , Clorexidina , Suscetibilidade à Cárie Dentária , Riboflavina , Dentina
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