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1.
Cureus ; 16(2): e54754, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38524015

RESUMO

The carotid body, situated at the common carotid artery bifurcation, comprises specialized glomus cells responsible for sensing blood oxygen, carbon dioxide, pH, and temperature changes, crucial for regulating breathing and maintaining oxygen homeostasis. Carotid body tumors (CBTs), arising from these cells, are rare, representing only 0.5% of head and neck tumors, often presenting as benign, slow-growing, vascularized masses. In February 2023, this bibliometric analysis was conducted, which involved screening 1733 articles from the Web of Science database. The screening process was based on citation count, and articles were selected for inclusion based on specific criteria that focused on CBTs located within the carotid bifurcation. Rigorous selection involved independent screening and data extraction by four authors. The top 100 articles, published between 1948 and 2019, totaled 6623 citations and were authored by 98 unique first authors from 22 countries and 77 institutions, spanning 42 journals. Treatment articles were the predominant category, comprising 49% of the literature. This analysis offers insights into publication trends, identifies literature gaps, and outlines areas of research focus, providing a valuable resource to guide future studies on CBTs.

2.
Cureus ; 16(1): e53147, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38420076

RESUMO

Dupuytren's disease (DD) is a fibroproliferative disorder that manifests as an abnormal growth of myofibroblasts, causing nodule formation and contractures and affecting digit function. If left untreated, these contractures can lead to a loss of mobility and potentially impact hand function. This systematic review critically compares and evaluates the existing literature on the complications and patient satisfaction following injectable collagenase Clostridium histolyticum (CCH) versus limited fasciectomy (LF) for DD. We performed a comprehensive search of the PubMed, Medical Literature Analysis and Retrieval System Online (MEDLINE), The Cochrane Library, and Excerpta Medica database (EMBASE) databases from 2006 to August 2023. This research targeted all clinical studies involving adults who underwent injectable collagenase and/or limited fasciectomy in the management of DD. Out of the 437 identified studies, only 53 were considered eligible for our analysis, and merely 14 met our inclusion criteria. These selected studies encompassed a total of 967 patients with 1,344 treated joints, with an average follow-up duration of 19.22 (ranging from one to 84.06) months. Within this cohort, 498 joints from 385 patients underwent LF, while 846 joints from 491 patients received CCH injections. Notably, among the 491 patients treated with CCH, 1,060 complications were reported, averaging 2.15 complications per patient, with the most common being contusion/bruising/hematoma/ecchymosis (22.54%), and edema/swelling (18.96%). In contrast, among the 385 patients treated with LF, only 97 complications were reported, translating to 0.25 complications per patient, with the most frequent being paraesthesia or numbness (23.7%), scar sequelae like skin laceration, tear, fissure, or hypertrophic scar (23.7%), and neuropraxia or nerve injury (22.6%). Our meta-analysis indicates that paraesthesia or numbness is more frequently observed in LF than CCH injections, although without statistical significance, with a risk ratio (RR) of 0.39 (95% confidence interval (CI) 0.13-1.18, p-value 0.1). However, scar sequelae (hypertrophic scar, skin laceration, tear, or fissure) show a contrasting pattern, being more commonly associated with CCH injections than LF, with an RR of 1.98 (95% CI 0.26-14.85, p-value 0.51), which, upon eliminating the source of heterogeneity, becomes statistically significant, with an RR of 4.98 (95% CI 1.40-17.72, p-value 0.01). Our data revealed a higher frequency of complications with CCH compared to LF, although more severe adverse effects were observed in the LF group, such as neuropraxia or nerve injury. Scar sequelae were more common with CCH injections. Despite both treatments showing increased patient satisfaction at the final follow-up, CCH injection resulted in earlier improvements in satisfaction.

3.
Cureus ; 15(4): e38328, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37261152

RESUMO

Background  Headache problems are among the most common medical conditions. There are major gaps in understanding headaches among healthcare practitioners. This study aimed to determine challenges and barriers to headache training among neurology residents in Saudi Arabia. Methods  A cross-sectional questionnaire-based study was conducted in Saudi Arabia. The target population was all Saudi neurology residents who were currently registered with the Saudi Commission for Health Specialties (SCHS). Statistical analysis was conducted using RStudio (R version 4.1.1). A chi-squared test is used for categorical variables whenever applicable. The statistical differences for continuous variables were assessed using a Wilcoxon rank sum test. Results A total of 227 respondents were included. More than half of the residents were male (56.8%). Large proportions of residents self-rated their knowledge as good for migraines (62.6%) and tension-type headaches (60.4%). The most experienced challenges included difficult diagnosis (30.4%) and treatment difficulties due to comorbidities (19.8%). The most stated barriers to optimal treatment of headache patients were the existence of challenges in collaboration between patient and therapist (24.7%). Most residents rely on the use of the International Classification of Headache Disorders (ICHD) in diagnosing and managing headache patients instead of the Saudi guidelines. The most reported reason for headache referral was suspicion of an underlying serious disease (31.7%). The most recommended non-pharmacological interventions were exercise (15.9%). Conclusion  We found that residents reported the diagnosis of headache as the most challenging barrier. The overuse of analgesics played a role in causing the headache. The most often cited barrier to providing headache patients with the best possible care was difficulties in patient-therapist collaboration. Ongoing headache education and comprehensive academic training are recommended to enhance knowledge during neurology residency training and offer competent care for their patients.

4.
Cureus ; 15(3): e36595, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-37095809

RESUMO

Background Breast cancer is the most common of all female cancers worldwide. A large percentage are diagnosed at a late stage, which can be related to awareness and knowledge deficiency. We aimed to assess the level of knowledge of and attitude to breast cancer and breast self-examination in Jeddah, Saudi Arabia. Methodology A descriptive cross-sectional study was carried out among 392 women in Jeddah, Saudi Arabia. Using a non-probability sampling technique, a self-administered validated questionnaire was distributed via social media. Inclusion criteria were ages above 18 years old of all educational levels. Results Out of 392 participants, there were 146 in the age group of 19-25 (37.2%). Most of the participants are aware of breast cancer (94.9%). The mean knowledge score was 6.9 ± 3.36. Ninety-two percent (92%) of participants had poor knowledge. Most respondents reported that the main risk factor for breast cancer was family history (83.7%). About 37% believed that the purpose of the breast self-examination practice is advice from a health care professional followed by routine examination (37.3%). About 97% agreed that early detection of breast cancer increases the chance of recovery. Conclusion There is a lack of knowledge and awareness about the risk factors and symptoms of breast cancer. Despite a positive attitude toward breast self-examination, it is poorly practiced.

5.
Cureus ; 15(2): e35339, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36994265

RESUMO

BACKGROUND: Obstructive sleep apnea (OSA) is characterized by chronic, recurrent episodes of partial or complete airway obstruction during sleep. It has a negative impact on quality of life and behavior and can lead to adverse neurological and cardiovascular outcomes if left untreated. This study aims to assess the awareness and knowledge of pediatric OSA among parents attending a general pediatric clinic in Jeddah, Saudi Arabia. METHODS: An observational cross-sectional study was conducted from October 2022 to December 2022, on parents who attended the pediatric clinic at Dr. Soliman Fakeeh Hospital in Jeddah. Participants were asked to complete a self-administered questionnaire, either using a tablet or a paper-based survey. The questionnaire consisted of sociodemographic information and questions assessing the parents' knowledge and awareness of pediatric OSA. RESULTS: The study included 146 participants. The mean knowledge score was 15.38 ± 6. Only 20% of the participants had a good knowledge level, while 80% had a poor level of knowledge. Furthermore, regarding the definition of OSA, 60 out of 146 participants answered correctly. Enlargement of adenoids was the most recognized risk factor, and restless sleep was the most recognized symptom. The majority of participants agreed that consulting an expert doctor was the best method to raise awareness about childhood OSA. CONCLUSION: The result of our study reveals the low level of awareness and knowledge of pediatric OSA among parents attending a pediatric clinic in Jeddah. This highlights the need for health education programs and sensitization campaigns to improve awareness of pediatric obstructive sleep apnea.

6.
Epilepsy Behav Rep ; 16: 100475, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34505052

RESUMO

PURPOSE: Epilepsy is one of the most common neurological disorders, with a national prevalence of 6.54/1000. The majority of the patients are adolescents and at risk of experiencing a seizure in school. Consequently, schoolteachers would be among the first health care providers. Thus, teachers' knowledge and practice are imperative for the students' safety and development. We aimed to assess the knowledge of epilepsy and seizure first aid among teachers at all educational levels in Jeddah, Saudi Arabia. METHOD: A cross-sectional study using a self-administered validated questionnaire was distributed to teachers to assess their necessary demographic data and their knowledge about epilepsy and seizure first aid by using Chi-square test to find significant associations. RESULTS: Our sample included 822 teachers, 54.1% of the respondents were male, and 45.7% female. The majority of participants had moderate knowledge of epilepsy and lacked first aid training. Most participants recognized epilepsy as a neurological disorder, and 42.2% have witnessed a seizure in school. Our study showed a significant relationship between knowledge score and qualification (P-value = 0.037) as well as knowledge score and witnessing a seizure (P-value = 0.046). CONCLUSION: The knowledge score shows that teachers in Jeddah have moderate knowledge of epilepsy, and approximately one-tenth have taken first aid training. We recommend educational campaigns on epilepsy and first aid courses targeting students and teachers in schools.

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