Prevalence of Anxiety and Depression and Their Association With Migraine Among PHC Center Visitors in Madina, Saudi Arabia.

INTRODUCTION: This cross-sectional study addresses the global rise in mental health disorders, emphasizing the bidirectional relationship between migraines and conditions such as depression and anxiety. This study seeks to bridge a crucial gap by examining the prevalence of depression and anxiety and their potential role as predictors of migraine. METHODS: This study included 407 participants aged 16 and above, attending one of the major PHC centers in Madinah city between August 1, 2023, and October 1, 2023. The study employed the Migraine Screening Questionnaire (MS-Q) for migraine screening and the Patient Health Questionnaire-4 (PHQ-4) for identifying anxiety and depression. RESULTS: Among the 407 participants included in our study, the prevalence of anxiety and depression was 9.1% and 5.9%, respectively. The prevalence of individuals experiencing both anxiety and depression was 3.7%. Anxiety exhibited a robust and statistically significant prediction of having migraines (OR: 4, P<0.05), while depression showed no statistically significant association. Gender, working frequency, and a higher level of education emerged as significant predictors of anxiety. Conversely, working multiple shifts and increased coffee consumption were found to be protective against anxiety. Regarding depression, spending more screen time and a higher education level were identified as significant predictors, while higher coffee intake and current smoking status were protective against depression. CONCLUSIONS: This cross-sectional study concluded that anxiety significantly predicts having migraines, while depression did not emerge as a statistically significant predictor. The study's outcomes underscore the imperative for mental health screening and management in individuals with migraines in PHC settings. However, comprehensive efforts are warranted to be applied across diverse cities and demographics to attain a more nuanced understanding of this association.

A Case Report of Migraine With Hypoplasia of the Internal Carotid Artery.

Migraine, a widespread and incapacitating neurological disorder, affects numerous individuals worldwide, causing severe headaches and impairing their quality of life. The interplay of genetic, environmental, and neurovascular factors underlies the pathophysiology of migraine. This report highlights the case of a 25-year-old woman with recurrent, severe headaches, predominantly in the right frontal and temporal regions. She was diagnosed with migraine with aura, a diagnosis supported by her family history. No previous history of seizures was reported. A comprehensive work-up, including neuroimaging, revealed left internal carotid artery hypoplasia with compensatory collateral circulation. The coexistence of severe migraines and left internal carotid artery hypoplasia underscores the complex interrelationship between cerebrovascular anomalies and neurological symptoms. The rarity of this vascular variation emphasizes the need for attentive clinical evaluation and consideration of anatomical deviations in migraine patients. As medical knowledge progresses, further research is essential to unravel the mechanisms connecting vascular anomalies and neurological disorders, ultimately leading to personalized interventions for improved patient outcomes.