RESUMO
CONTEXT AND OBJECTIVE: Use of mammography for breast cancer screening has resulted in a significantly increased number of patients with nonpalpable radiological findings that need histopathological study for better management. The present study evaluated an alternative to excision of nonpalpable breast lesions, using injection of patent blue (CAS 3536-49-0) dye and air. DESIGN AND SETTING: Cohort study of 64 consecutive patients at a private clinic in the city of Teresina (Piauí), between January 2009 and December 2010. METHODS: The patients had received mammographic diagnoses of nonpalpable breast lesions classified as BI-RADS 3, 4 and 5, with indication of histopathological study. They underwent stereotaxy and/or ultrasound-guided injection of patent blue, for marking and subsequent excision of the lesion. RESULTS: The patients' mean age was 47.7 years. Nodes accounted for 53.1% of the breast abnormalities; microcalcifications, 37.5%; and complex cysts, 9.4%. In 89.1% of cases, the lesions were BI-RADS 4; 7.8% were BI-RADS 5 and 3.1% were BI-RADS 3. The histopathological findings were benign in 70.3% of the cases; atypical hyperplasia, 9.4%; and malignant, 20.3%. Among the malignant cases, 53.8% were carcinoma in situ and 46.2%, invasive carcinoma. The percentage of malignancy was 0% in BI-RADS 3 lesions; 14.3% in BI-RADS 4 and 100% in BI-RADS 5. In the cases of malignancy, the margins were clear in 92.3%. Reoperation to widen the margins was required in one patient. CONCLUSION: Excision of nonpalpable breast lesions marked with patent blue and air was possible in all cases.
Assuntos
Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Carcinoma/patologia , Carcinoma/cirurgia , Mastectomia Segmentar/métodos , Corantes de Rosanilina , Adulto , Ar , Biópsia , Mama/patologia , Neoplasias da Mama/diagnóstico por imagem , Carcinoma/diagnóstico por imagem , Detecção Precoce de Câncer , Feminino , Humanos , Hiperplasia/patologia , Mamografia , Pessoa de Meia-Idade , Duração da Cirurgia , Reprodutibilidade dos Testes , Estudos Retrospectivos , Resultado do TratamentoRESUMO
CONTEXT AND OBJECTIVE: Use of mammography for breast cancer screening has resulted in a significantly increased number of patients with nonpalpable radiological findings that need histopathological study for better management. The present study evaluated an alternative to excision of nonpalpable breast lesions, using injection of patent blue (CAS 3536-49-0) dye and air. DESIGN AND SETTING: Cohort study of 64 consecutive patients at a private clinic in the city of Teresina (Piauí), between January 2009 and December 2010. METHODS : The patients had received mammographic diagnoses of nonpalpable breast lesions classified as BI-RADS 3, 4 and 5, with indication of histopathological study. They underwent stereotaxy and/or ultrasound-guided injection of patent blue, for marking and subsequent excision of the lesion. RESULTS : The patients' mean age was 47.7 years. Nodes accounted for 53.1% of the breast abnormalities; microcalcifications, 37.5%; and complex cysts, 9.4%. In 89.1% of cases, the lesions were BI-RADS 4; 7.8% were BI-RADS 5 and 3.1% were BI-RADS 3. The histopathological findings were benign in 70.3% of the cases; atypical hyperplasia, 9.4%; and malignant, 20.3%. Among the malignant cases, 53.8% were carcinoma in situ and 46.2%, invasive carcinoma. The percentage of malignancy was 0% in BI-RADS 3 lesions; 14.3% in BI-RADS 4 and 100% in BI-RADS 5. In the cases of malignancy, the margins were clear in 92.3%. Reoperation to widen the margins was required in one patient. CONCLUSION: Excision of nonpalpable breast lesions marked with patent blue and air was possible in all cases. .
CONTEXTO E OBJETIVOS: A utilização da mamografia no rastreamento para o câncer de mama tem apresentado significativo aumento do número de pacientes com achados radiológicos impalpáveis que, para melhor orientação terapêutica, necessitam de estudo histopatológico. O presente estudo avaliou uma alternativa à ressecção de lesões impalpáveis de mama utilizando injeção de corante azul patente e ar. TIPO DE ESTUDO E LOCAL: Coorte de 64 casos consecutivos de uma clínica particular da cidade Teresina (PI), no período de janeiro de 2009 a dezembro de 2010. MÉTODOS: As pacientes receberam o diagnóstico mamográfico de lesões impalpáveis de mama classes BI-RADS 3, 4 e 5 com indicação para estudo histopatológico. Elas foram submetidas à injeção de azul patente, orientada por estereotaxia e/ou ultrassonografia para marcação e posterior ressecção da lesão. RESULTADOS: A média de idade das pacientes foi 47,7 anos. Os nódulos representaram 53,1% das anormalidades; as microcalcificações, 37,5% e os cistos complexos, 9,4%. Em 89,1% dos casos, as lesões eram BI-RADS 4; 7,8%, BI-RADS 5 e 3,1%, BI-RADS 3. Os achados histopatológicos foram benignos em 70,3% dos casos; com hiperplasia atípica em 9,4% e malignos em 20,3%. Dos casos de malignidade, 53,8% eram carcinoma in situ e 46,2%, carcinoma invasor. O percentual de câncer foi 0% nas lesões BI-RADS 3;14,3% nas BI-RADS 4 e 100% nas BI-RADS 5. Nos casos de neoplasia maligna, as margens estavam livres em 92,3%, sendo necessária reoperação para ampliação de margens em uma paciente. CONCLUSÃO: A ressecção de lesões impalpáveis de mama marcadas com azul patente e ar foi possível em todos os casos. .
