RESUMO
Because of its rarity, the diagnosis of optic nerve medulloepithelioma poses a real diagnostic challenge. Medulloepithelioma is a congenital tumor that derives from the primitive medullary epithelium present in the neural tube and the optic vesicle. Its classical location is the ciliary body. Cases of retinal or optic nerve locations have been rarely reported in the literature. Only 11 cases have been published in the English literature. Herein, we report the case of a 2-year-old boy who underwent enucleation of the right eye for a presumed diagnosis of right-eye retinoblastoma, based on the presence of leukocoria on ophthalmological examination. Pathological examination showed an optic nerve medulloepithelioma. A review of the literature is also discussed in our work.
Assuntos
Tumores Neuroectodérmicos Primitivos , Neoplasias da Retina , Retinoblastoma , Masculino , Humanos , Pré-Escolar , Tumores Neuroectodérmicos Primitivos/patologia , Nervo Óptico/patologia , Retinoblastoma/patologia , Corpo Ciliar/patologia , Neoplasias da Retina/patologia , Enucleação OcularRESUMO
Introduction: Breast angiosarcoma is a rare, aggressive tumour affecting adult women. It can occur in two forms, primary form and secondary forms or radiation-induced breast angiosarcoma affecting patients with history of breast or chest radiotherapy. Case presentation: The authors report a new case of breast angiosarcoma in 52-year-old women, with history of invasive ductal carcinoma, and reporting a discoloration of her breast skin. The patient did undergo a mastectomy of right breast and adjuvant chemotherapy. Conclusion/discussion: Surgery with total excision associated or not to adjuvant chemotherapy remains the treatment of choice in breast angiosarcoma.
Assuntos
Adenocarcinoma/diagnóstico , Mesonefroma/diagnóstico , Neoplasias Vaginais/diagnóstico , Adenocarcinoma/patologia , Adenocarcinoma/terapia , Feminino , Humanos , Queratinas/metabolismo , Mesonefroma/patologia , Mesonefroma/terapia , Pessoa de Meia-Idade , Neprilisina/metabolismo , Neoplasias Vaginais/patologia , Neoplasias Vaginais/terapiaRESUMO
Primary leiomyosarcomas of the thyroid gland are extremely rare. we report a case of a 72 year-old women with a painful growing mass of the left neck with skin fistula. The patient underwent a lobectomy. The tumor histology showed spindle-shaped cells arranged in interlacing fascicles that expressed desmine and H-caldesmone, but were negative for cytokeratins and thyroglobulin. Total body CT scan didn't show any other tumor. The patient died two months after surgery. Primary thyroid leiomyosarcoma may be mistaken for other tumors, such as anaplastic or medullary carcinomas. Therefore, the diagnosis is difficult and requires numerous clinical, radiological, and pathological investigations. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1917621950869224.