[The nature of an anticoagulant isolated from peonies in the central zone of Russia]. / K voprosu o prirode antikoagulianta, poluchennogo iz pionov srednei polosy Rossii.

The nature of the anticoagulant isolated from the Chinese peony roots has been determined. Physicochemical analysis (infrared and mass spectroscopy, and polyacrylamide gel electrophoresis) demonstrated the presence of a glycopeptide in Paeonia suffraticosae roots. This glycopeptide shares a structural similarity with heparin.

[Heparin from the meadowsweet (Filipendula ulmaria) and its properties]. / Geparin iz tavolgi viazolistnoi, ego svoistva.

In the present work, the nature of an anticoagulant from Philipendula ulmaria was studied. A method for purification of this anticoagulant was developed. Using diverse methods it was shown that the molecular weight, data on element (sulphur, nitrogen, and hydrogen) content, spectral characteristics in the infrared region of the spectrum, and electrophoretic properties of the product indicate its similarity to heparin of animal origin.

[The antibacterial activity of a humic preparation made from the therapeutic peat mud of the Dzalal Abad deposit in Kirghizia]. / Antibakterial'naia aktivnost' guminovogo preparata iz lechebnoi torfianoil griazi Dzhalal-Abadskogo mestorozhedeniia Kirgizii.

The humic acid from the Dzhalal Abad therapeutic peat muds has been extracted to reveal the mechanisms of interaction between humic acid and microelements in therapeutic muds and to study the mud physiologically active factor. A complex compound of copper with humic and aminoacetic acids has been obtained, their physicochemical and antibacterial properties have been studied.

[Physicochemical properties of the diabetogenic factor and its complex with heparin]. / Nekotorye fiziko-khimicheskie svoistva diabetogennogo faktora i ego kompleksa s geparinom.

The diabetogenic factor (DGF) isolated from the human blood and the blood of rats with diabetes mellitus was shown to be a protein homogeneous at electrophoresis in gel of polyacrylamide, with the molecular weight of 60,000 D. The interaction of DGF with heparin results in the formation of a complex in which the factor's properties are blocked and those of heparin as a anticoagulant are preserved.

[Complex formation of heparin with the inhibitor of non-enzymatic fibrinolysis isolated from the spleen]. / Kompleksobrazovanie geparina s ingibitorom nefermentativnogo fibrinoliza, vydelennym iz tkani selezenki.

Formation of complexes between heparin and protein inhibitor of non-enzymatic fibrinolysis, isolated from spleen tissue of healthy animals, was demonstrated by means of cross electrophoresis, UV- and IR-spectrophotometries. Suppression of the spleen inhibitor activity towards non-enzymatic fibrinolysis occurred via its complex-formation with heparin, where the inhibitor aminogroups reacted with sulfo- or carboxyl groups of heparin.