RESUMO
Microalgal-bacterial consortium (MBC) constitutes a sustainable and efficient alternative to the conventional activated sludge process for wastewater treatment (WWT). Recently, integrating the MBC process with nitritation (i.e., shortcut MBC) has been proposed to achieve added benefits of reduced carbon and aeration requirements. In the shortcut MBC system, nitrite or free nitrous acid (FNA) accumulation exerts antimicrobial influences that disrupt the stable process performance. In this review, the formation and interactions that influence the performance of the MBC were firstly summarized. Then the influence of FNA on microalgal and bacterial monocultures and related mechanisms together with the knowledge gaps of FNA influence on the shortcut MBC were highlighted. Other challenges and future perspectives that impact the scale-up of the shortcut MBC for WWT were illustrated. A potential roadmap is proposed on how to maximize the stable operation of the shortcut MBC system for sustainable WWT and high-value biomass production.