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Eur Arch Otorhinolaryngol ; 280(2): 713-721, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-35849188

RESUMO

OBJECTIVES: To comprehensively analyse the disease presentation and mortality of COVID-associated rhino-orbito-cerebral mucormycosis. METHODS: A retrospective analysis of the demographics, clinical and radiographic findings was performed. A binary logistic regression analysis was performed to examine the survival of patients with mucormycosis from hypothesised predictors. RESULTS: A total of 202 patients were included in this study. Statistical significance was demonstrated in the predilection to the male gender, recent history of SARS-COV-2, history of use of corticosteroid and hyperglycemia in this cohort of CAM. The mortality rate was 18.31%. Advanced age, raised HbA1c and intra-orbital extension were found to be predictors adversely affecting survival. CONCLUSION: Early diagnosis, aggressive surgical therapy, early and appropriate medical therapy can help improve outcomes. LEVEL OF EVIDENCE: Level 4.


Assuntos
COVID-19 , Mucormicose , Doenças Orbitárias , Humanos , Masculino , Mucormicose/complicações , Mucormicose/diagnóstico , Mucormicose/terapia , Estudos Retrospectivos , COVID-19/complicações , SARS-CoV-2 , Nariz , Doenças Orbitárias/diagnóstico , Doenças Orbitárias/terapia , Antifúngicos/uso terapêutico
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