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1.
Opt Express ; 32(11): 18700-18716, 2024 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-38859020

RESUMO

A Fe-InP-based planar array antenna-coupled InGaAs/InAlAs multiple quantum well (MQW) optical phase modulator is proposed and demonstrated for radio over fiber (RoF) applications with 60 GHz-band millimeter-wave wireless signals. The modulator comprises five types of five-layer asymmetric coupled quantum wells (FACQWs) and a two-element array antenna. The FACQWs are designed to have a significant electric-field-induced refractive index change with small electric fields induced in the antenna. In the fabricated modulator, a carrier-to-sideband ratio (CSR) of up to 45.9 dB was successfully obtained at a power density of 11 W/m2, corresponding to a phase shift of 10.1 mrad. Furthermore, data transmission of a 2 GHz modulated wave with a 60 GHz wireless carrier wave was demonstrated.

2.
Sensors (Basel) ; 24(10)2024 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-38794104

RESUMO

A high-sensitivity silicon microring (Si MRR) optical biosensor for detecting the nucleocapsid protein of SARS-CoV-2 is proposed and demonstrated. In the proposed biosensor, the surface of a Si MRR waveguide is modified with antibodies, and the target protein is detected by measuring a resonant wavelength shift of the MRR caused by the selective adsorption of the protein to the surface of the waveguide. A Si MRR is fabricated on a silicon-on-insulator substrate using a CMOS-compatible fabrication process. The quality factor of the MRR is approximately 20,000. The resonant wavelength shift of the MRR and the detection limit for the environmental refractive index change are evaluated to be 89 nm/refractive index unit (RIU) and 10-4 RIU, respectively. The sensing characteristics are examined using a polydimethylsiloxane flow channel after the surface of the Si MRR waveguide is modified with the IgG antibodies through the Si-tagged protein. First, the selective detection of the protein by the MRR sensor is experimentally demonstrated by the detection of bovine serum albumin and human serum albumin. Next, various concentrations of nucleocapsid protein solutions are measured by the MRR, in which the waveguide surface is modified with the IgG antibodies through the Si-tagged protein. Although the experimental results are very preliminary, they show that the proposed sensor has a potential nucleocapsid sensitivity in the order of 10 pg/mL, which is comparable to the sensitivity of current antigen tests. The detection time is less than 10 min, which is much shorter than those of other antigen tests.


Assuntos
Técnicas Biossensoriais , Proteínas do Nucleocapsídeo de Coronavírus , SARS-CoV-2 , Silício , Técnicas Biossensoriais/instrumentação , Técnicas Biossensoriais/métodos , Silício/química , SARS-CoV-2/isolamento & purificação , SARS-CoV-2/imunologia , Humanos , Proteínas do Nucleocapsídeo de Coronavírus/imunologia , COVID-19/diagnóstico , COVID-19/virologia , Fosfoproteínas , Limite de Detecção
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