RESUMO
Case Report A healthy 55-years-old male went to emergency due to a white infiltrate in the left eye without corneal trauma which partially responds to antibiotic treatment. The infiltrate worsened by the use of topical steroids. Direct microscopic evaluation and Gram stain are a valuable diagnostic tool for the detection of Absidia filaments. There is a successful treatment with anphotericin and posaconazole. Discussion Keratitis caused by Zygomicetes are unusual. This is a rare condition in healthy patients with no corneal trauma. The treatment with amphotericin and posaconazole are synergistic against filamentous fungi.
Assuntos
Absidia/isolamento & purificação , Úlcera da Córnea/etiologia , Mucormicose/microbiologia , Absidia/efeitos dos fármacos , Administração Oftálmica , Corticosteroides/efeitos adversos , Anfotericina B/uso terapêutico , Antibacterianos/uso terapêutico , Antifúngicos/uso terapêutico , Terapia Combinada , Transplante de Córnea , Úlcera da Córnea/tratamento farmacológico , Úlcera da Córnea/microbiologia , Úlcera da Córnea/cirurgia , Quimioterapia Combinada , Humanos , Imunocompetência , Masculino , Pessoa de Meia-Idade , Mucormicose/diagnóstico , Mucormicose/tratamento farmacológico , Soluções Oftálmicas , Coloração e Rotulagem , Triazóis/uso terapêutico , Voriconazol/uso terapêuticoRESUMO
CLINICAL CASE: A 5 year-old child diagnosed with moderate anisometropic amblyopia secondary to primary cyst of iris pigment epithelium. He was evaluated with ultrasound biomicroscopy (BMU) and optical coherence tomography (OCT) of anterior segment. DISCUSSION: The OCT, although with some limitations, is a useful tool to study the anterior segment. It is probably more recommendable than BMU in the childhood.
Assuntos
Ambliopia/etiologia , Oftalmopatias Hereditárias/complicações , Iris/anormalidades , Epitélio Pigmentado Ocular/anormalidades , Tomografia de Coerência Óptica , Astigmatismo/etiologia , Catarata/complicações , Pré-Escolar , Oftalmopatias Hereditárias/diagnóstico por imagem , Humanos , Iris/diagnóstico por imagem , Masculino , Microscopia Acústica , Epitélio Pigmentado Ocular/diagnóstico por imagem , Lâmpada de FendaRESUMO
CASE REPORT: A 64 year-old female with Parkinson disease treated with amantadine for two years who suddenly suffered bilateral corneal oedema. It was initially treated as herpetic endotheliitis without improvement as we lacked information on her chronic treatment. The corneal oedema finally resolved after withdrawing the drug. DISCUSSION: Amantadine hydrochloride may produce endothelial dysfunction. Once the amantadine treatment is stopped, the corneal oedema may be reversible but endothelial density remains low. An ophthalmologist examination should be performed before the initiation of amantadine treatment in order to establish a risk: benefit ratio, especially in those patients with low endothelial density or any endothelial anomaly.