The role of right temporo-parietal junction in stimulus evaluation.

A predominant model of the temporo-parietal junction (TPJ) claims that this region is critical for attentional orienting/reorienting toward an unexpected, but behaviorally significant stimulus. However, recent studies have suggested that the TPJ is also involved in the process of evaluating stimulus, especially matching between external sensory inputs and internal representations. While some studies provide evidence for the involvement of the TPJ in stimulus evaluation, the nature of the evaluative process mediated by the TPJ remains unclear. To address this issue, we tested whether the TPJ activation amplitude and its peak latency is proportional to the demand of the evaluative process. We found that when the amount of sensory evidence for the matching process was abundant, the TPJ was transiently activated. Importantly, the TPJ activation showed a greater and more sustained pattern while the sensory evidence was accumulating for a longer period of time. These findings suggest that the TPJ function is associated with the evaluative process of matching sensory inputs with internal representations, as well as attentional reorienting.

The perceptual enhancement by spatial attention is impaired during the attentional blink.

A salient, but task-irrelevant stimulus has long been known to capture attention in an automatic, involuntary manner. However, the automaticity of involuntary attention has recently been challenged. While some studies showed that the effect of involuntary attention depended on top-down attentional resources, other studies did not. To reconcile this conflict, we suggest to consider that attentional effect is not homogenous. Specifically, we hypothesized that the dependence of involuntary attention on top-down attention interacts with the presence/absence of the target location uncertainty and distractor interference. Consistent with this hypothesis, we found that when the attentional resources were depleted, the involuntary attention did not affect the perception of a single target stimulus (Experiment 1). However, when the target was accompanied by multiple distractors, evoking uncertainty regarding the target location, the involuntary attentional effect was observed, regardless of the availability of attentional resource (Experiment 2). This was so, even when the target location was always marked by a response cue, minimizing the target location uncertainty (Experiment 3). These findings provide a reconciliation for the theoretical debate regarding the dependence of involuntary attention on top-down attention and clarifies how perception is modulated by involuntary attention.

Neural substrates of purely endogenous, self-regulatory control of attention.

Stimulus-driven orienting of attention toward a novel, salient stimulus is a highly adaptive behavior. In an opposing vein, it is also crucial to endogenously redirect attention to other stimuli of behavioral significance if the attended stimulus was evaluated to be unimportant. This stimulus-driven orienting and subsequent reorienting of attention are known to be mediated by similar neural substrates. However, this might be because reorienting was triggered by a sensory transition exogenously capturing attention, such as an abrupt onset of a new stimulus. Here, we used fMRI to measure the human brain's activity when attention captured by a salient distractor is endogenously reoriented toward the concurrent main task, without any exogenous shifting of attention. As results, the transient activity of the anterior insula (AI) signaled such endogenous reorienting, predicting behavioral performance. This finding points to the central role of the AI in purely endogenous, self-regulatory control of attention.