Assuntos
Biomarcadores Tumorais/biossíntese , Proteínas Inibidoras de Apoptose/biossíntese , Leucemia Mielogênica Crônica BCR-ABL Positiva/tratamento farmacológico , Proteína 3 com Repetições IAP de Baculovírus , Progressão da Doença , Resistencia a Medicamentos Antineoplásicos/genética , Regulação Neoplásica da Expressão Gênica , Humanos , Prognóstico , Inibidores de Proteínas Quinases/uso terapêutico , Ubiquitina-Proteína LigasesRESUMO
The influence of Cracow's urban pollution on small forest ecosystems was studied during 1998-2000. Seven sites located at different distances from the Cracow conurbation and from busy road were selected. Two sites were situated 26 and 31 km from Cracow town along an eastern transect, the other five-3, 8, 14, 26 and 35 km respectively, from Cracow-along a southern transect. At the beginning of September, five litter traps were set at each site. The quantity of litter fall, along with percentage composition of each species, were estimated for an area of 1 m(2). The concentration of Cd, Pb, Cu, Zn and Fe in the litter fall and the input of these metals to the forest floor were determined. The input of cadmium ranged from 84 microg m(-2) at Kornatka in 1998 to 382 microg m(-2) at Bonarka in 2000. The input of lead was about 10 times higher than cadmium and varied from 406 microg m(-2) at Weglówka in 1998 to 3717 microg m(-2) at Bonarka in 2000. Input of Cu, Zn and Fe to the forest floor showed the similar tendency. During 1998-2000, the highest heavy metal concentrations in the litter fall and their impact on the forest floor were always found at sites close to the Cracow conurbation and, in the eastern transect, close to a steel works. Input of metals to the forest floor tended to decrease with increasing distance from the centre of Cracow.