Real-Time 3D Microwave Medical Imaging With Enhanced Variational Born Iterative Method.

In this paper, we present a new variational Born iterative method (VBIM) for real-time microwave imaging (MWI) applications. The S-parameter volume integral equation and waveport vector Green's function are implemented to utilize the measured signal of the MWI system. Meanwhile, the real and imaginary separation (RIS) approach is used at each iterative step to simultaneously reconstruct the dielectric permittivity and conductivity of unknown objects. Compared with the Born iterative method and distorted Born iterative method, VBIM requires less computational time to reach the convergence threshold. The graphics processing unit based acceleration technique is implemented for real-time imaging. To demonstrate the efficiency and accuracy of this VBIM-RIS method, synthetic analysis of a complex multi-layer spherical phantom is first conducted. Then, the algorithm is tested with measured data using our new MWI system prototype. Finally, a synthetic brain-tumor phantom model under a thermal therapy procedure is monitored to exemplify the real-time imaging with about 5 seconds per reconstruction frame.

A Versatile and Shelf-Stable Dielectric Coupling Medium for Microwave Imaging.

OBJECTIVE: To develop a new class of emulsions using a protein-based emulsifier as the coupling fluid for microwave imaging systems. METHODS: In this paper, we provide a theoretical basis for engineering shelf-stable dielectric fluids, a step-by-step formulation method, and measurements of complex dielectric properties in the frequency range of 0.5-3 GHz, which can be applicable for many of the recent microwave imaging systems. RESULTS: This medium was primarily designed for long-term stability while providing a controllable range of complex dielectric permittivities given different fractions of its constituents. Consequently, this emulsion shows dielectric stability in open air throughout a 7-day experiment and temperature insensitivity over the range of 0 ° C to 60 ° . CONCLUSIONS: This control over dielectric permittivity enables formulations that tune the background-to-target contrast to the linearizable regime of iterative inverse scattering algorithms. Accordingly, the emulsion conductivity can also be controlled and reduced to maintain the required signal-to-noise ratio within the dynamic range of the imaging system. The new formulation overcomes the practical challenges of engineering coupling fluids for microwave imaging systems, e.g., temporal stability, non-toxic, low sensitivity to temperature variation, and easy formulation from readily available and inexpensive materials. SIGNIFICANCE: The achieved properties associated with this new fluid are of particular benefit to microwave imaging systems used in thermal therapy monitoring.