The relations between COVID-19 stress, social connectedness, and mental health: a longitudinal investigation comparing Chinese and American college students.

College students in the U.S. and China have faced significant challenges during COVID-19. Data were collected from 120 Amerian students (Mage = 19.48, SDage = 1.30) and 119 Chinese students (Mage = 18.61, SDage = 0.91) in November, 2019 and March, 2020 to examine risk and protective factors for mental health (depression, anxiety, life satisfaction) during the pandemic, and potential cultural and gender differences. Results indicated that the frequency and impact of COVID-19-related stressful life events predicted deterioration of mental health over time, while social connectedness before the pandemic buffered the negative impact of COVID-19 stressful life events on life satisfaction. Chinese students reported higher levels of social connectedness and larger impact of COVID-19-related stressful life events, but lower frequency of stressful life events than American students. Stressful life events and social connectedness predicted mental health outcomes similarly for Chinese and American students. Gender differences were identified. Females reported more stressful life events, higher levels of depression, anxiety and less life satisfaction during COVID-19 than males. In addition, the frequency of stressful life events had a stronger impact on depression and anxiety for females compared with males. It is important to implement prevention and intervention programs to promote social connections and wellbeing among college students, especially among female students.

Theileria orientalis outbreak in an organized cattle breeding farm.

Theileriosis is an important tick borne disease of cattle caused by a haemoprotozoan of genus Theileria. Clinical bovine theileriosis is mainly caused by T. annulata or T. parva but the clinical disease due to T. orientalis is rare. T. orientalis mainly infect RBCs and causes "Oriental theileriosis" or Theileria-associated bovine anaemia in cattle and other livestock species. Two genotypes of T. orientalis (Chitose and Ikeda) are reported to cause severe disease in some countries. In this report, a spontaneous outbreak of Oriental theileriosis was studied in an organized Holstein-Friesian cattle breeding farm situated in the south-eastern Himalayan ranges of Himachal Pradesh State of India. Animal blood and tick samples were tested using cytological and PCR techniques. The disease episode occurred in a protracted manner spanning over 10 to 12 months and association of T. orientalis was confirmed in 93.3% of the blood and 21.7% of Rhipicephalus microplus (tick) samples. No other tick borne pathogen was detected except Anaplasma marginale in two blood samples. Haematological profiling of infected cattle showed characteristic indicators of anaemia like haemoblobin, RBC count, haematocrit value and mean corpuscular volume at either lower than normal or near the lower normal range. The prevailing persistent anaemic changes led to more severe clinical manifestations like abortion and joint inflammation. The detected T. orientalis strains and ticks species were further confirmed by nucleotide sequence analysis of 18S rRNA and 16S rRNA genes. Phylogenetically, T. orientalis strains showed clustering with other reported strains of T. orientalis from the surrounding regions. This first report of clinical Oriental theileriosis from India emphasises the importance of T. orientalis as an emerging tick borne pathogen and role of widely prevalent ticks species in disease transmission and their impact on livestock production.

A review: Lumpy skin disease and its emergence in India.

Lumpy skin disease (LSD) is a viral disease caused by lumpy skin disease virus (LSDV), a member of Capripoxvirus genus of Poxviridae family. It is a transboundary disease of the economic importance affecting cattle and water buffaloes. The disease is transmitted by arthropod vectors and causes high morbidity and low mortality. LSD has recently been reported first time in India with 7.1% morbidity among cattle. Generally, fever, anorexia, and characteristic nodules on the skin mucous membrane of mouth, nostrils, udder, genital, rectum, drop in milk production, abortion, infertility and sometimes death are the clinical manifestations of the disease. The disease is endemic in African and Middle East countries but has started spreading to Asian and other countries. It has been recently reported from China and Bangladesh sharing borders with India. We have summarized occurrence of LSD outbreaks in last 10 years in Asian countries for the first time. In India, currently epidemiological status of the disease is unknown. Vaccination along with strict quarantine measures and vector control could be effective for preventing the spread of the disease. This review aims to summarise the latest developments in the epidemiology with the focus on transboundary spread, aetiology and transmission, clinical presentations, diagnostics and management of the disease.