[Case report: oral malignant melanoma in an 11-month-old Dobermann]. / Fallbericht: Malignes orales Melanom bei einem 11 Monate alten Dobermann.

Oral malignant neoplasms are very common in old dogs. The prognosis of oral malignant melanoma (MM) for long-term survival is poor, because of early metastasis and delayed diagnosis. Oral MM in immature dogs is rare. A case of oral MM in an immature dog is described. The diagnostic workup includes radiographs of the tumor and thorax, a cytologic examination of the regional lymph nodes and a biopsy of the tumor. The therapy with the best chance of success is the radical surgical excision of the tumor.

[Pectineus myectomy, tenotomy of the iliopsoas and neurectomy of the joint capsule as symptomatic therapy for coxarthrosis of the dog]. / Die Pectineusmyektomie, Iliopsoastenotomie und Neurektomie der Gelenkkapsel (PIN) als symptomatische Therapie bei der Coxarthrose des Hundes.

Abduction and extension of the hip is reduced and painful in patients with coxarthrosis. Contracture of the pectineus and iliopsoas muscles restricts the abduction and extension of the hip, respectively. Pectineus myectomy and tenotomy of the iliopsoas muscle result in clinical improvements. This symptomatic therapy is relatively simple, with minimal invasion. Clinical results are satisfactory.

Effects of adrenaline, dopamine, serotonin, and different cholinergic agents on smooth muscle preparations from the ansa proximalis coli in cattle: studies in vitro.

The effects of adrenaline, dopamine, serotonin, and different cholinergic agents on isolated muscle strips from the ansa proximalis coli in cattle were studied. Adrenaline (5 x 10(-5) mol/l) evoked a relaxing effect (p < 0.05) on longitudinal and circular muscle strips, mediated via beta- and alpha 1-receptors respectively. High concentration of dopamine (5 x 10(-4) mol/l) caused a non-significant inhibitory effect on longitudinal smooth muscles, which was probably mediated by beta- and not by dopamine-receptors. Serotonin (5 x 10(-5) mol/l) and cisapride (75 x 10(-6) mol/l) had no effect. Carbachol (2 or 10 x 10(-6) mol/l) and bethanechol (5 or 10 x 10(-5) mol/l) caused a dose-dependent (p < 0.05) contraction of both smooth muscle types. This excitatory effect was inhibited (p < 0.05) by metoclopramide (1 x 10(-4) mol/l), as well as the muscarinic agents RS-86 (5 x 10(-5) mol/l) and CGP-37,218 (37.5 or 75 x 10(-6) mol/l).