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Diagn Cytopathol ; 37(3): 164-9, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19170167

RESUMO

The objective of the present study was to assess infections and cytologic abnormalities in cervicovaginal smears from 153 HIV-positive women and 169 HIV-negative followed up at the UFTM School of Medicine between May 1999 and May 2002. The medical records and cervicovaginal smears were reviewed and the HIV-positive group was classified according to CD4 cell count, HIV viral load, antiretroviral therapy and HIV subgroups (with or without disease; with or without therapy) and compared to HIV-negative group. We conclude that the frequency of Candida sp, Trichomonas vaginalis and bacterial vaginosis in cervicovaginal smear, is not different between HIV-positive and HIV-negative women, even if the HIV-group is subdivided according to CD4 cell count, HIV viral load, antiretroviral therapy and HIV subgroups. The frequency of LSIL, in cervicovaginal smears, was greater in the HIV-group (17.6%) than in the HIV-negative (4.1%); there was no difference between the two groups according to frequency of HSIL (4.6% versus 1.8%), ASCUS/AGUS (7.8% versus 3.5%) and invasive carcinoma (1.3% versus 0.6%). The frequency of LSIL was greater in the HIV positive group with CD4 cell count < 350 cells/mm(3). The viral load, therapeutic regimen and HIV subgroups (HIV-positive without therapy, HIV-positive with therapy, AIDS by immunological criteria and AIDS by clinical criteria) have not shown relationship with LSIL frequency, until now.


Assuntos
Carcinoma de Células Escamosas/patologia , Infecções por HIV/patologia , Neoplasias do Colo do Útero/patologia , Vaginose Bacteriana/patologia , Adulto , Animais , Contagem de Linfócito CD4 , Candida/isolamento & purificação , Carcinoma de Células Escamosas/complicações , Chlamydia/isolamento & purificação , Feminino , Gardnerella vaginalis/isolamento & purificação , Infecções por HIV/complicações , Infecções por HIV/microbiologia , Humanos , Trichomonas vaginalis/isolamento & purificação , Neoplasias do Colo do Útero/classificação , Esfregaço Vaginal , Vaginose Bacteriana/complicações , Vaginose Bacteriana/microbiologia , Carga Viral
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