1.
Bioorg Med Chem Lett
; 22(24): 7376-80, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23131342
RESUMO
We report the optimization of a series of non-steroidal GR antagonists that led to the identification of compound 7. This compound is efficacious when dosed orally in an olanzapine-induced weight gain model in rats.