RESUMO
BACKGROUND: Perineuriomas are tumours derived from the perineurial cells of the neural sheath. Soft tissue perineuriomas are rare. Herein, we report a case of perineurioma localized to the nose. CASE REPORT: A 24-year-old adult presented with a cutaneous nodule 1cm in diameter localized on the nose. Histologically, the tumour corresponded to a well-circumscribed fusocellular dermal proliferation organized in a storiform pattern. After surgical removal, the lesion did not recur. COMMENTS: Extraneural soft tissue perineurioma is usually a benign nerve sheath tumour composed mainly of perineurial cells. Our case occurred in a 24-year-old Caucasian adult. The tumour generally presents as a unique cutaneous nodule corresponding histologically to a well-delineated dermal fusocellular proliferation organized in a storiform pattern that stains positive for EMA and negative for S100. The tumour is usually localized to the trunk and extremities. Location on the nose as in our patient has been rarely reported. Surgical removal of the tumour is the treatment of choice.
Assuntos
Neoplasias de Bainha Neural/patologia , Neoplasias Nasais/patologia , Antígenos CD34/análise , Biomarcadores Tumorais , Humanos , Masculino , Mucina-1/análise , Neoplasias de Bainha Neural/química , Neoplasias de Bainha Neural/diagnóstico , Neoplasias de Bainha Neural/cirurgia , Neoplasias Nasais/química , Neoplasias Nasais/diagnóstico , Neoplasias Nasais/cirurgia , Adulto JovemRESUMO
BACKGROUND: Primary testicular lymphoma is the most common testicular malignancy in the elderly, account for 1% of all non Hodgkin lymphoma (NHL). The aim was to report from new cases of testicular lymphoma CASES: We report the only four cases of testicular lymphoma observed in a period of 15 years; all these cases were primary diffuse large cell B NHL. Disease course is usually aggressive, with widespread organ involvement. Retrospective analyses show a poor prognosis for this presentation.
Assuntos
Linfoma/diagnóstico , Neoplasias Testiculares/diagnóstico , Adulto , Idoso , Humanos , Linfoma/patologia , Linfoma de Células B/diagnóstico , Linfoma de Células B/patologia , Linfoma Difuso de Grandes Células B/diagnóstico , Linfoma Difuso de Grandes Células B/patologia , Masculino , Pessoa de Meia-Idade , Necrose , Invasividade Neoplásica , Prognóstico , Estudos Retrospectivos , Neoplasias Testiculares/patologiaRESUMO
BACKGROUND: Extramedullary plasmocytoma is rare, with less than 50 reported cases and only 8 cases of primary testicular plasmocytoma. AIM: Report of a new case CASE: This report concerns a 65-year-old patient presenting an enlargement of the testis. The diagnosis of testicular plasmocytoma was made on histological examination. There was no evidence of bone marrow involvement or systemic signs of myeloma. This case will be studied with a review of the literature.