RESUMO
We describe a case of H1N1 pneumonia with left upper lobe bronchial atresia. Although bronchial atresia as an isolated occurrence is an innocuous finding, but when it is superimposed by another major insult, it can amplify the disease effect and can have adverse implications leading to significant morbidity. This report highlights the fact that anatomical anomalies can be the cause of inordinately severe or prolonged course of acute respiratory infection in children.
Assuntos
Brônquios/diagnóstico por imagem , Influenza Humana/diagnóstico por imagem , Pneumonia Viral/diagnóstico por imagem , Anormalidades do Sistema Respiratório/diagnóstico por imagem , Brônquios/anormalidades , Broncoscopia , Criança , Feminino , Humanos , Vírus da Influenza A Subtipo H1N1 , Influenza Humana/complicações , Influenza Humana/terapia , Pneumonia Viral/complicações , Pneumonia Viral/terapia , Radiografia Torácica , Anormalidades do Sistema Respiratório/complicações , Anormalidades do Sistema Respiratório/diagnóstico , Tomografia Computadorizada por Raios XAssuntos
Lesão Pulmonar Aguda/induzido quimicamente , Bleomicina/efeitos adversos , Óleo Etiodado/efeitos adversos , Pneumonia Lipoide/induzido quimicamente , Escleroterapia/efeitos adversos , Bleomicina/administração & dosagem , Pré-Escolar , Meios de Contraste/efeitos adversos , Feminino , Humanos , Soluções Esclerosantes/administração & dosagem , Soluções Esclerosantes/efeitos adversos , Malformações Vasculares/terapiaRESUMO
BACKGROUND: We conducted a sero-survey among pregnant women attending antenatal clinics of six hospitals which also function as sentinel sites for CRS surveillance, to estimate the prevalence of IgG antibodies against rubella. METHODS: We systematically sampled 1800 pregnant women attending antenatal clinics and tested their sera for IgG antibodies against rubella. We classified sera as seropositive (titre ≥10â¯IU/ml), sero-negative (titre <8â¯IU/ml) or indeterminate (titre 8-9.9â¯IU/ml) per manufacturer's instructions. In a sub-sample, we estimated the titers of IgG antibodies against rubella. IgG titer of ≥10â¯IU/mL was considered protective. RESULTS: Of 1800 sera tested, 1502 (83.4%) were seropositive and 24 (1.3%) were indeterminate and 274 (15.2%) were sero-negative. Rubella sero-positivity did not differ by age group, educational status or place of residence. Three hundred and eighty three (87.8%) of the 436 sera had IgG concentrations ≥10â¯IU/mL. CONCLUSION: The results of the serosurvey indicate high levels of rubella sero-positivity in pregnant women. High sero-prevalence in the absence of routine childhood immunization indicates continued transmission of rubella virus in cities where sentinel sites are located.
Assuntos
Anticorpos Antivirais/sangue , Complicações Infecciosas na Gravidez/epidemiologia , Rubéola (Sarampo Alemão)/epidemiologia , Adolescente , Adulto , Estudos Transversais , Feminino , Humanos , Imunoglobulina G/sangue , Índia/epidemiologia , Gravidez , Gestantes , Prevalência , Vírus da Rubéola , Vigilância de Evento Sentinela , Estudos Soroepidemiológicos , Centros de Atenção Terciária , Vacinação/estatística & dados numéricos , Adulto JovemRESUMO
An infant aged 6 weeks presented with failure to thrive since birth, fever and lethargy for 4 days. The child was fed on unpasteurised diluted goat's milk after birth. She was diagnosed to have brucellosis both by blood culture and serology. Her mother's Brucella serology was negative. She was successfully treated with injection amikacin and tablet rifampicin and had satisfactory weight gain thereafter. Acquired brucellosis should be considered in the differential diagnosis of failure to thrive in young infants.