The structural and functional connectivity of the grassland plant Lychnis flos-cuculi.

Understanding the relationship between structural and functional connectivity is essential for successful restoration and conservation management, particularly in intensely managed agricultural landscapes. We evaluated the relationship between structural and functional connectivity of the wetland plant Lychnis flos-cuculi in a fragmented agricultural landscape using landscape genetic and network approaches. First, we studied the effect of structural connectivity, such as geographic distance and various landscape elements (forest, agricultural land, settlements and ditch verges), on gene flow among populations as a measurement of functional connectivity. Second, we examined the effect of structural graph-theoretic connectivity measures on gene flow among populations and on genetic diversity within populations of L. flos-cuculi. Among landscape elements, forests hindered gene flow in L. flos-cuculi, whereas gene flow was independent of geographic distance. Among the structural graph-theoretic connectivity variables, only intrapopulation connectivity, which was based on population size, had a significant positive effect on gene flow, that is, more gene flow took place among larger populations. Unexpectedly, interpopulation connectivity of populations, which takes into account the spatial location and distance among populations, did not influence gene flow in L. flos-cuculi. However, higher observed heterozygosity and lower inbreeding was observed in populations characterised by higher structural interpopulation connectivity. This finding shows that a spatially coherent network of populations is significant for maintaining the genetic diversity of populations. Nevertheless, lack of significant relationships between gene flow and most of the structural connectivity measures suggests that structural connectivity does not necessarily correspond to functional connectivity.

Multiple ciliary body cysts and secondary glaucoma in the Great Dane: a report of nine cases.

Between 1989 and 1995 nine Great Danes were presented to the small animal clinic of the University of Zurich Teaching Hospital with glaucoma and multiple cysts in the anterior and posterior chamber. In four of the nine dogs cysts were present in both eyes; however, bilateral glaucoma was seen in one case only. Mean intraocular pressure (IOP) at initial presentation was 42 mmHg measured by applanation tonometry. With the exception of one dog, all animals were treated medically for a minimum of 13 days. Two animals were subsequently lost to follow up. Two dogs underwent evisceration with implantation of a silicone prosthesis. The glaucomatous globe was enucleated in three dogs. One owner declined surgery and the dog remained buphthalmic with a poorly controlled IOP. One animal remained visual after trans-scleral diode laser cyclophotocoagulation. Histopathology of the three enucleated globes showed multiple cysts originating from the ciliary body epithelium. The mechanism of IOP elevation is probably by anterior displacement of the iris with narrowing of the angle and collapse of the ciliary cleft. A delicate pre-iridal fibrovascular membrane was also seen in each case, which could have also contributed to the elevation of IOP. The high odds ratio of 2.23 (CI 95% 1.14, 3.99) for glaucoma and 37.01 (CI 95% 16.42, 77.81) for ciliary body cysts suggests they are both inherited in this breed. Pedigree analysis of the affected dogs failed to definitely reveal the mode of inheritance.

[Intascleral silicone prosthesis in the dog: a retrospective study of 22 cases]. / Intrasklerale Silikonprothesen beim Hund: eine retrospektive Studie von 22 Fällen.

Over a period of five years 28 dog eyes were treated by evisceration and implantation of an intrascleral silicone prosthesis. During an average follow-up period of 2.93 years the only complication noted was a mild entropion in one case. The majority of dog owners were satisfied with the cosmetic result. All of them would again opt for this procedure and prefer it to an enucleation. The postoperative management was well tolerated by both animals and owners. After careful preoperative work-up and ruling-out of intraocular neoplasms, evisceration/prosthesis is a simple and practical method to salvage buphthalmic eyes and globes with beginning phthisis bulbi. Intraocular tumors and septic endophthalmitis are the two principal contraindications. In addition, eyes with deep or even perforated corneal ulcers should not be fitted with an intrascleral prosthesis.

[Prolapse of the eyeball in small animals: a retrospective study of 36 cases]. / Der Prolapsus bulbi beim Kleintier. Eine retrospektive Studie von 36 Fällen.

Proptosis of the globe is an ophthalmic emergency, which requires rapid assessment of the situation and immediate medical and surgical therapy. The relevant prognostic signs as well as the medical and surgical management are discussed. A retrospective study of 36 proptosed globes at the Zurich Veterinary School revealed that young animals with a mean age of 5.2 years (dogs) and 4.7 years (cats) are at risk. In the dog both sexes are equally at risk, while tomcats have a higher incidence than females. In ten cases immediate enucleation of the proptosed globe was necessary. The remaining eyes could be replaced. The majority of the repositioned globes were subsequently blind, the cosmetic result, however, was satisfactory according to most owners. Ophthalmic follow-up examinations revealed a large number of long-term damages in repositioned eyes in dogs and cats concerning anterior and posterior segment.

[Eye injuries in the dog caused by cat claws]. / Augenverletzungen durch Katzenkrallen beim Hund.

A retrospective study of ocular cat claw injuries in the dog revealed an over-representation of very young dogs in our case material. Puppies up to the age of 12 weeks have no menace response. Thus, an important protective mechanism is missing in early life. This may be one reason for the frequently occurring severe ocular trauma caused by cat claw injuries in puppies. Older dogs are less likely to sustain such an injury. Cat claw injuries cause corneal and lens capsule perforation with ensuing severe phacoclastic uveitis. In our series phthisis bulbi or secondary glaucoma were the result in 50% of the cases. In large lens capsule tears early lens extraction may prevent severe uveitis and may retain functional vision.