Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros








Base de dados
Intervalo de ano de publicação
1.
Biomed Res Int ; 2017: 6960810, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28316985

RESUMO

Objectives. Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases (IBD) with unclear underlying aetiologies. Severe cardiac arrhythmias have been emphasised in a few studies on adult IBD patients. This study aimed to investigate the alteration of the P-wave and QT interval dispersion parameters to assess the risk of atrial conduction and ventricular repolarisation abnormalities in pediatric IBD patients. Patients and Methods. Thirty-six IBD patients in remission (UC: 20, CD: 16) aged 3-18 years and 36 age- and sex-matched control patients were enrolled in the study. Twelve-lead electrocardiograms were used to determine durations of P-wave, QT, and corrected QT (QTc) interval dispersion. Transthoracic echocardiograms and 24-hour rhythm Holter recordings were obtained for both groups. Results. The P-wave dispersion, QT dispersion, and QTc interval dispersion (Pdisp, QTdisp, and QTcdisp) were significantly longer in the patient group. The mean values of Pminimum, Pmaximum, and QTcminimum were significantly different between the two groups. The echocardiography and Holter monitoring results were not significantly different between the groups. Furthermore, no differences in these parameters were detected between the CD and UC groups. Conclusion. Results suggest that paediatric IBD patients may carry potential risks for serious atrial and ventricular arrhythmias over time even during remission.


Assuntos
Arritmias Cardíacas/complicações , Colite Ulcerativa/complicações , Doença de Crohn/complicações , Sistema de Condução Cardíaco/fisiopatologia , Síndrome do QT Longo/fisiopatologia , Adolescente , Arritmias Cardíacas/fisiopatologia , Estudos de Casos e Controles , Criança , Pré-Escolar , Colite Ulcerativa/fisiopatologia , Doença de Crohn/fisiopatologia , Ecocardiografia , Eletrocardiografia , Eletrocardiografia Ambulatorial , Feminino , Frequência Cardíaca , Humanos , Masculino , Estudos Prospectivos , Indução de Remissão , Risco
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA