Acute urine retention following medullary compression of metastatic breast cancer in the spinal cord: Rare symptomatlogic presentation and management.

The management of locally advanced and metastatic breast cancer has evolved since 2021, with confirmation of the role of cell cycle inhibitors. The discovery of breast cancer is often the result of self-examination through the discovery of a nodule, but may also be due to symptoms at the metastatic site. The spinal cord is one of the rare sites of metastatic breast cancer involvement. We report the management of a rare case of metastatic breast cancer in the spinal cord, discovered following acute urinary retention.

Management of a localized prostatic adenocarcinoma despite the very high rate of PSA and the large tumor mass: Does PSA level indicate the stage of prostate cancer?

Prostate-specific antigen (PSA) is a marker specific to the prostate gland, and it is, therefore, possible to observe an increase in PSA above 4 ng/mL in cases of benign prostatic hypertrophy and cancer. But according to studies, a very high PSA level is most likely synonymous with metastatic prostate cancer. Our rare case concerns the management of a localized prostatic adenocarcinoma despite a very high PSA level of over 3000 ng/mL, with an enormous volume of prostate without invasion or distant metastasis. A very high PSA level can probably be a sign of metastatic prostatic adenocarcinoma, but not necessarily.

A rare case report of bile duct compression by a polycystic kidney treated by total nephrectomy after embolization.

INTRODUCTION AND IMPORTANCE: Polycystic kidney disease is a cillopathy characterized by the formation of numerous cysts in the kidneys, sometimes associated with extra-renal forms. Diagnosis is often by chance, or by other complications such as hematuria, urinary tract infections or, rarely, compression of neighboring organs. CASE PRESENTATION: We report the case of a patient consulted for a symptomatology similar to that of acute pancreatitis, whose investigation objectified compression of the main bile duct by a voluminous right kidney polycystic in a CT scan. CLINICAL DISCUSSION: For this compressive complication of the polycystic kidney, a nephrectomy was performed after embolization of the renal artery, given the haemorrhage risk. CONCLUSION: A polycystic kidney should be removed in the event of a compressive complication and, given the risk of haemorrhage, should preferably be preceded by embolization.