[Neonatal botriomycoma of the tongue (a case report)]. / Botryomycome lingual néonatal (à propos d'une observation).

INTRODUCTION: The botryomycoma is a benign tumor that develops as a response to a local trauma. Generally, it occurs in the fingers, the face and the oral cavity. It is often easily recognized. However, the diagnosis between this tumor and other oral tumors, whether benign or malignant, may be difficult in some cases. We report a particular case of a botryomycoma that occurred with no history of a trauma at an earlier age in the tongue, which is an unusual site for this tumor. CASE REPORT: A 7-month-old infant presented with a polypoid and sessile swelling on the dorsal side of the tongue. This tumor gradually increased in size since birth. Clinically, the appearance of this mass with the gathered vessels inside was similar to that of a benign vascular tumor. A possibly malignant nature was not excluded. A complete resection under general anesthesia was performed. The histologic examination confirmed the diagnosis of pyogenic granuloma. DISCUSSION: Pyogenic granuloma is a rare benign tumor which is most likely to occur between the age of 11 and 40. The most frequent location encountered for oral cavity is the gingiva. The tongue is rarely a site for its occurrence. Cutaneous pyogenic granuloma may have different aspect from mucosal type and thus may make the diagnosis difficult. Treatment consists on surgical excision and removal of etiological factors that may be source of recurrence.

[Marjolin's ulcer of the cheek developed on burn scar: a case report]. / Ulcère de Marjolin de la joue développé sur cicatrice de brûlure : à propos d'une observation.

Marjolin ulcers are scar carcinomas most often arising in old burn injuries. They arise mostly in the extremities. We report medical history of a 50-year-old female suffering from a scar carcinoma on her right cheek which was histopathologically identified as a mean differentiated squamous cell carcinoma.

Obstructive congenital epulis.

INTRODUCTION: Congenital epulis, known as a congenital gingival granular cell tumor, is a benign tumor and very rare in newborns. Voluminous or multiple tumors can cause mechanical obstruction of the oral cavity and may result in postnatal feeding and respiratory problems. DISCUSSION: We report the clinical case of a female full-term newborn who presented a tumor on the upper gum obtruding into the oral cavity discovered at birth. The pregnancy was followed normally with three prenatal ultrasounds, which did not show abnormalities. The mass was excised under local anesthesia on the second day of life. The outcome was good after surgery and regular feedings were started on the second postoperative day. Histological examination confirmed the diagnosis of gingival tumor with granular cells and absence of signs of malignancy. CONCLUSION: Prenatal diagnosis is fundamental in the therapeutic approach to this rare lesion but remains difficult because the findings are non specific and the generally late development of the tumor.

[Epithelioid hemangioendothelioma mimicking an occipital artery aneurysm]. / Hémangioendothéliome épithélioïde simulant un anévrisme de l'artère occipitale.

INTRODUCTION: Epithelioid hemangioendothelioma (EHE) is a unique tumor of soft tissues, primarily occurring in adults. It is characterized by the proliferation of epithelioid or histiocytoid endothelial cells. Its clinical course being close to that of hemangioma and conventional angiosarcoma, the term epithelioid hemangioendothelioma was suggested. CASE REPORT: The authors report the case of 29-year-old women complaining of a right occipital nodule of the scalp, diagnosed later as an epithelioid hemangioendothelioma located in the scalp and appearing like an aneurysm of the occipital artery on clinical examination and on radiological investigations. On first clinical examination this tumor mimicked a sebaceous cyst. However during history taking we noted headaches and palpation revealed a pulsatile mass with a thrill. An aneurysm of the occipital artery was suspected according to ultra-sound and MRI findings. The treatment was a wide and complete excision of the lesion. Finally it was the histological examination which confirmed the diagnosis of epithelioid hemangioendothelioma. There was no evidence of local recurrence at the twelve-month follow-up. DISCUSSION: This case is unusual on the following points: a rare occurrence of this kind of tumors, especially in the scalp region, arterial origin of the tumor, but also the fact that it mimicked an aneurysm of the occipital artery. Epithelioid hemangioendotheliomas belong to the epithelioid vascular tumor spectrum. They have in common the morphologic epithelioid aspect of endothelial tumor cells. Cutaneous involvement is rare and often associated with multi-systemic localizations.

Immunohistochemical localization of a retinoic acid-like receptor in nerve cells of two colonial anthozoans (Cnidaria).

Retinoic acid is known to induce vertebrate stem cells to differentiate into a variety of cell types, including neurons. Although retinoic acid was reported to affect morphogenetic pattern specification in the hydrozoan Hydractinia (Müller, W.A., 1984. Retinoids and pattern formation in a hydroid. J. Embryol. Exp. Morph. 81, 253-271) and a retinoid RXR receptor was cloned in the jellyfish Tripedalia (Kostrouch, Z., Kostrouchova, M., Love, W., Jannini, E., Piatigorsky, J., Rall, J.E., 1998. Retinoic acid X receptor in the diploblast, Tripedalia cystophora. Proc. Natl. Acad. Sci. U.S.A. 95, 13442-13447), the cellular targets of retinoids were not investigated. We used Western immunoblotting and immunohistochemistry to investigate the presence and cellular distribution of a RXR-like receptor in the sea pansy Renilla koellikeri and in the staghorn coral Acropora millepora (Cnidaria, Anthozoa). Western blots revealed a 64 kDa protein from a sea pansy extract in a band that co-migrated with a RXR protein from the rat brain. Using antibodies raised against an epitope of human alpha RXR, we visualized putative ectodermal sensory cells in the polyp column of the adult sea pansy. Immunoreactivity was absent in staghorn coral larvae but present in the polyp column of adult colonies in the form of clusters of neuron-like cells in the basiectoderm near the ectoderm-mesoglea interface. These observations suggest that a RXR-like receptor is involved in epithelial nerve cell specification in adult anthozoans and that this role is conserved throughout evolution.

[Salivary duct carcinoma]. / Carcinome des canaux salivaires.

INTRODUCTION: Salivary duct carcinoma is a very rare tumor of the salivary glands that has been principally reported in the parotid gland. It displays histologically a striking similarity to ductal carcinoma of the breast. OBSERVATION: We report the case of a salivary duct carcinoma arising in the parotid gland of a 62 year-old man. The fact that the tumor was confined to the parotid gland has allowed a radical treatment. After two year follow-up, there was no evidence of recurrence. DISCUSSION: This tumor is characterized clinically by local aggressiveness, frequent metastatic evolution and poor prognosis. This case report illustrates both the clinicopathological features and the prognostic factors of this entity.

[Lipoma of the infratemporal fossa. Apropos of a case]. / Lipome de la fosse intra-temporale. A propos d'un cas.

Lipomas of the infratemporal fossa are rare. We report a case that underlines the importance of imaging for diagnosis and treatment. We discuss the incidence, pathogenesis and diagnostic problems as well as therapeutic options for lipomas of the infratemporal fossa.

[Postoperative blindness after buccal tumorectomy and bilateral radical neck dissection]. / Cécité postopératoire après tumorectomie buccale et curage cervical bilatéral.

A case of bilateral blindness in a 47-year-old patient after buccal tumorectomy and bilateral neck dissection is reported. The diagnosis of posterior optic ischaemia was substantiated by the features of blindness and the negativity of cerebral CT-scanography and NMR imaging. The respective roles of atherosclerosis, arterial hypotension, acute anaemia and increased intracranial pressure are discussed. Preventive measures include a strict control of blood pressure, blood loss and head position.

[Ossifying periostitis (Garrè) and chronic sclerosing osteomyelitis. Diagnostic limits and therapeutic management]. / Périostite ossifiante (Garrè) et ostéomyélite chronique sclérosante. Frontières diagnostiques et conduite thérapeutique.

Periostitis ossificans and sclerosing osteomyelitis are rare subtypes of non suppurative chronic osteomyelitis in which there is, additionally, a proliferation of periosteum leading to bony deposition secondary to a mild chronic infection making their diagnosis difficult. The authors report two clinical cases and try to release criteria helping to discern them because the prognosis and therapeutic management of these affections are different.

[Craniofacial bone abnormalities in von Recklinghausen neurofibromatosis]. / Les anomalies osseuses cranio-faciales dans la neurofibromatose de Von Recklinghausen.

Cases of cranio-facial bone anomalies were observed in 40 cases of neurofibromatosis. The cranio-facial skeletal manifestations are numerous and varied. Radiographic investigation is important to confirm the diagnosis, when neurologic and cutaneous signs are absent. The diagnosis should be easily confirmed by a conventional radiographic study.

[Maxillo-mandibular fibrous dysplasia in 2 brothers]. / Dysplasie fibreuse maxillo-mandibulaire chez deux frères.

The authors report two cases of maxillo-mandibular fibrous dysplasia showing different form and grow up features affecting two brothers without notion inherited transmission of the lesion. By the way, the diagnostic and the therapeutic management are discussed.

[Irreversible bilateral blindness after functional neck dissection. Apropos of a case and a review of the literature]. / Cécité bilatérale irréversible après curage cervical fonctionnel bilatéral. A propos d'un cas et revue de la littérature.

Postoperative blindness due to ischemic optic neuropathy is a rare and dramatic complication. A review of the literature from 1960 until nowadays reveal several physiopathological mechanisms of the blindness. Through the description of their clinic case of a fourty seven years old man showing definitive postoperative blindness after sustaining surgery for epidermoid carcinoma of the mouth floor, the authors suggest as etiology the conjunction of the following factors: brain venous high pressure, head and neck oedema, hypotension and the vascular state of the patient. Special perioperative care taking in account the risk factors is needed to prevent this complication.

[Osteochondroma of the mandibular condyle. Apropos of a case]. / Ostéochondrome du condyle mandibulaire. A propos d'un cas.

The authors report a case of mandibular condyle osteochondroma on a 33 years-old woman, similar to osteocartilaginous exostosis of the long bones. The lesion was revealed by a facial asymmetry and a change of the occlusion. The diagnosis was performed on the computed-tomography examination and histopathology. The removal of the lesion has conserved the condyle without recurrence after 20 months following-up. The authors remind the uncommonly location of osteochondroma in the facial skeleton and discuss the histogenesis of this lesion in its mandibular condyle site.

[Solitary plasmacytoma. Apropos of a case of craniofacial involvement]. / Plasmocytome solitaire. A propos d'un cas de localisation cranio-faciale.

The authors report the case of a 24 years-old man who had a first tumor in the right maxilla diagnosed as Ewing's sarcoma and treated by chemotherapy and radiotherapy. A second tumor appeared in the skull vault twenty seven months later. The histological diagnosis after removal of the lesion was IgG Lambda plasmacytoma. The revision of the histological cut of the maxillary tumor retained the same diagnosis. The patient is without evidence of local recurrence and systemic diffusion of the disease two years after treatment. The authors insist on the necessity of immunochemistry to establish the diagnosis.