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1.
Phys Rev Lett ; 117(19): 192001, 2016 Nov 04.
Artigo em Inglês | MEDLINE | ID: mdl-27858429

RESUMO

Ultrahigh energy cosmic ray air showers probe particle physics at energies beyond the reach of accelerators. Here we introduce a new method to test hadronic interaction models without relying on the absolute energy calibration, and apply it to events with primary energy 6-16 EeV (E_{CM}=110-170 TeV), whose longitudinal development and lateral distribution were simultaneously measured by the Pierre Auger Observatory. The average hadronic shower is 1.33±0.16 (1.61±0.21) times larger than predicted using the leading LHC-tuned models EPOS-LHC (QGSJetII-04), with a corresponding excess of muons.

2.
Phys Rev Lett ; 116(24): 241101, 2016 Jun 17.
Artigo em Inglês | MEDLINE | ID: mdl-27367377

RESUMO

We measure the energy emitted by extensive air showers in the form of radio emission in the frequency range from 30 to 80 MHz. Exploiting the accurate energy scale of the Pierre Auger Observatory, we obtain a radiation energy of 15.8±0.7(stat)±6.7(syst) MeV for cosmic rays with an energy of 1 EeV arriving perpendicularly to a geomagnetic field of 0.24 G, scaling quadratically with the cosmic-ray energy. A comparison with predictions from state-of-the-art first-principles calculations shows agreement with our measurement. The radiation energy provides direct access to the calorimetric energy in the electromagnetic cascade of extensive air showers. Comparison with our result thus allows the direct calibration of any cosmic-ray radio detector against the well-established energy scale of the Pierre Auger Observatory.

3.
Science ; 349(6253): 1228-32, 2015 Sep 11.
Artigo em Inglês | MEDLINE | ID: mdl-26229117

RESUMO

Cyclic GMP-AMP synthase (cGAS) detects cytosolic DNA during virus infection and induces an antiviral state. cGAS signals by synthesis of a second messenger, cyclic GMP-AMP (cGAMP), which activates stimulator of interferon genes (STING). We show that cGAMP is incorporated into viral particles, including lentivirus and herpesvirus virions, when these are produced in cGAS-expressing cells. Virions transferred cGAMP to newly infected cells and triggered a STING-dependent antiviral program. These effects were independent of exosomes and viral nucleic acids. Our results reveal a way by which a signal for innate immunity is transferred between cells, potentially accelerating and broadening antiviral responses. Moreover, infection of dendritic cells with cGAMP-loaded lentiviruses enhanced their activation. Loading viral vectors with cGAMP therefore holds promise for vaccine development.


Assuntos
Infecções por HIV/imunologia , HIV-1/metabolismo , Herpes Simples/imunologia , Herpesvirus Humano 1/metabolismo , Interferon beta/imunologia , Nucleotídeos Cíclicos/metabolismo , Sistemas do Segundo Mensageiro , Vírion/metabolismo , Vacinas contra a AIDS/imunologia , Células Dendríticas/imunologia , Células Dendríticas/virologia , Genes Reporter , Vetores Genéticos/genética , Vetores Genéticos/metabolismo , Células HEK293 , Infecções por HIV/metabolismo , Infecções por HIV/prevenção & controle , HIV-1/genética , Herpes Simples/prevenção & controle , Vacinas contra o Vírus do Herpes Simples/imunologia , Herpesvirus Humano 1/genética , Humanos , Imunidade Inata/genética , Imunidade Inata/imunologia , Interferon beta/genética , Regiões Promotoras Genéticas , Ativação Transcricional , Vírion/genética
4.
Phys Rev Lett ; 108(7): 072301, 2012 Feb 17.
Artigo em Inglês | MEDLINE | ID: mdl-22401196

RESUMO

We report new STAR measurements of midrapidity yields for the Λ, Λ[over ¯], K(S)(0), Ξ(-), Ξ[over ¯](+), Ω(-), Ω[over ¯](+) particles in Cu+Cu collisions at √S(NN)==200 GeV, and midrapidity yields for the Λ, Λ[over ¯], K(S)(0) particles in Au+Au at √S(NN)==200 GeV. We show that, at a given number of participating nucleons, the production of strange hadrons is higher in Cu+Cu collisions than in Au+Au collisions at the same center-of-mass energy. We find that aspects of the enhancement factors for all particles can be described by a parametrization based on the fraction of participants that undergo multiple collisions.

5.
Phys Rev Lett ; 106(6): 062002, 2011 Feb 11.
Artigo em Inglês | MEDLINE | ID: mdl-21405460

RESUMO

We report the first measurement of the parity-violating single-spin asymmetries for midrapidity decay positrons and electrons from W+ and W- boson production in longitudinally polarized proton-proton collisions at sqrt[s] = 500 GeV by the STAR experiment at RHIC. The measured asymmetries, A(L)(W+) = -0.27 ± 0.10(stat.) ± 0.02(syst.) ± 0.03(norm.) and A(L)(W-) = 0.14 ± 0.19(stat.) ± 0.02(syst.) ± 0.01(norm.), are consistent with theory predictions, which are large and of opposite sign. These predictions are based on polarized quark and antiquark distribution functions constrained by polarized deep-inelastic scattering measurements.

6.
Phys Rev Lett ; 104(20): 201801, 2010 May 21.
Artigo em Inglês | MEDLINE | ID: mdl-20867022

RESUMO

This Letter describes the current most precise measurement of the W boson pair production cross section and most sensitive test of anomalous WWγ and WWZ couplings in pp collisions at a center-of-mass energy of 1.96 TeV. The WW candidates are reconstructed from decays containing two charged leptons and two neutrinos. Using data collected by the CDF II detector from 3.6 fb(-1) of integrated luminosity, a total of 654 candidate events are observed with an expected background of 320±47 events. The measured cross section is σ(pp→W+ W- +X)=12.1±0.9(stat)-1.4+1.6(syst) pb, which is in good agreement with the standard model prediction. The same data sample is used to place constraints on anomalous WWγ and WWZ couplings.

7.
Phys Rev Lett ; 104(24): 241801, 2010 Jun 18.
Artigo em Inglês | MEDLINE | ID: mdl-20867293

RESUMO

Using data from 2.9 fb(-1) of integrated luminosity collected with the CDF II detector at the Tevatron, we search for resonances decaying into a pair of on-shell gauge bosons, WW or WZ, where one W decays into an electron and a neutrino, and the other boson decays into two jets. We observed no statistically significant excess above the expected standard model background, and we set cross section limits at 95% confidence level on G* (Randall-Sundrum graviton), Z', and W' bosons. By comparing these limits to theoretical cross sections, mass exclusion regions for the three particles are derived. The mass exclusion regions for Z' and W' are further evaluated as a function of their gauge coupling strength.

8.
Phys Rev Lett ; 104(25): 251801, 2010 Jun 25.
Artigo em Inglês | MEDLINE | ID: mdl-20867364

RESUMO

We present the results of a search for pair production of the supersymmetric partner of the top quark (the top squark t{1}) decaying to a b quark and a chargino χ{1}{±} with a subsequent χ{1}{±} decay into a neutralino χ{1}{0}, lepton ℓ, and neutrino ν. Using a data sample corresponding to 2.7 fb{-1} of integrated luminosity of pp collisions at sqrt[s]=1.96 TeV collected by the CDF II detector, we reconstruct the mass of top squark candidate events and fit the observed mass spectrum to a combination of standard model processes and t{1}t{1} signal. We find no evidence for t{1}t{1} production and set 95% C.L. limits on the masses of the top squark and the neutralino for several values of the chargino mass and the branching ratio B(χ{1}{±}→χ{1}{0}ℓ{±}ν).

9.
Phys Rev Lett ; 105(1): 012001, 2010 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-20867436

RESUMO

We report a measurement of the ratio of the tt to Z/γ{*} production cross sections in sqrt[s]=1.96 TeV pp collisions using data corresponding to an integrated luminosity of up to 4.6 fb{-1}, collected by the CDF II detector. The tt cross section ratio is measured using two complementary methods, a b-jet tagging measurement and a topological approach. By multiplying the ratios by the well-known theoretical Z/γ{*}→ll cross section predicted by the standard model, the extracted tt cross sections are effectively insensitive to the uncertainty on luminosity. A best linear unbiased estimate is used to combine both measurements with the result σ{tt}=7.70±0.52 pb, for a top-quark mass of 172.5 GeV/c{2}.

10.
Phys Rev Lett ; 105(10): 101801, 2010 Sep 03.
Artigo em Inglês | MEDLINE | ID: mdl-20867511

RESUMO

We present a measurement of the electric charge of the top quark using pp collisions corresponding to an integrated luminosity of 2.7 fb(-1) at the CDF II detector. We reconstruct tt events in the lepton + jets final state. We use soft lepton taggers to determine the flavor of the b jets, which we use to reconstruct the top quark's electric charge and exclude an exotic top quark with -4/3 charge at 95% confidence level. This is the strongest exclusion of the exotic charge scenario and the first to use soft leptons for this purpose.

11.
Phys Rev Lett ; 105(2): 022301, 2010 Jul 09.
Artigo em Inglês | MEDLINE | ID: mdl-20867701

RESUMO

We report the first three-particle coincidence measurement in pseudorapidity (Δη) between a high transverse momentum (p⊥) trigger particle and two lower p⊥ associated particles within azimuth |Δϕ|<0.7 in square root of s(NN)=200 GeV d+Au and Au+Au collisions. Charge ordering properties are exploited to separate the jetlike component and the ridge (long range Δη correlation). The results indicate that the correlation of ridge particles are uniform not only with respect to the trigger particle but also between themselves event by event in our measured Δη. In addition, the production of the ridge appears to be uncorrelated to the presence of the narrow jetlike component.

12.
Phys Rev Lett ; 105(2): 022302, 2010 Jul 09.
Artigo em Inglês | MEDLINE | ID: mdl-20867702

RESUMO

We report the first measurements of the kurtosis (κ), skewness (S), and variance (σ2) of net-proton multiplicity (Np-Np) distributions at midrapidity for Au+Au collisions at square root of s(NN)=19.6, 62.4, and 200 GeV corresponding to baryon chemical potentials (µB) between 200 and 20 MeV. Our measurements of the products κσ2 and Sσ, which can be related to theoretical calculations sensitive to baryon number susceptibilities and long-range correlations, are constant as functions of collision centrality. We compare these products with results from lattice QCD and various models without a critical point and study the square root of s(NN) dependence of κσ2. From the measurements at the three beam energies, we find no evidence for a critical point in the QCD phase diagram for µB below 200 MeV.

13.
Phys Rev Lett ; 105(4): 042002, 2010 Jul 23.
Artigo em Inglês | MEDLINE | ID: mdl-20867838

RESUMO

We report measurements of the polarization of W bosons from top-quark decays using 2.7 fb{-1} of pp collisions collected by the CDF II detector. Assuming a top-quark mass of 175 GeV/c{2}, three measurements are performed. A simultaneous measurement of the fraction of longitudinal (f{0}) and right-handed (f{+}) W bosons yields the model-independent results f{0}=0.88±0.11(stat)±0.06(syst) and f{+}=-0.15±0.07(stat)±0.06(syst) with a correlation coefficient of -0.59. A measurement of f{0} [f{+}] constraining f{+} [f{0}] to its standard model value of 0.0 [0.7] yields f{0}=0.70±0.07(stat)±0.04(syst) [f{+}=-0.01±0.02(stat)±0.05(syst)]. All these results are consistent with standard model expectations. We achieve the single most precise measurements of f{0} for both the model-independent and model-dependent determinations.

14.
Phys Rev Lett ; 105(8): 081802, 2010 Aug 20.
Artigo em Inglês | MEDLINE | ID: mdl-20868091

RESUMO

We report on a search for direct scalar bottom quark (sbottom) pair production in pp collisions at square root(s) = 1.96 TeV, in events with large missing transverse energy and two jets of hadrons in the final state, where at least one of the jets is required to be identified as originating from a b quark. The study uses a collider detector at Fermilab Run II data sample corresponding to 2.65 fb(-1) of integrated luminosity. The data are in agreement with the standard model. In an R-parity conserving minimal supersymmetric scenario, and assuming that the sbottom decays exclusively into a bottom quark and a neutralino, 95% confidence-level upper limits on the sbottom pair production cross section of 0.1 pb are obtained. For neutralino masses below 70 GeV/c2, sbottom masses up to 230 GeV/c2 are excluded at 95% confidence level.

15.
Phys Rev Lett ; 104(13): 131801, 2010 Apr 02.
Artigo em Inglês | MEDLINE | ID: mdl-20481871

RESUMO

The cross section for jets from b quarks produced with a W boson has been measured in pp collision data from 1.9 fb(-1) of integrated luminosity recorded by the CDF II detector at the Tevatron. The W+b-jets process poses a significant background in measurements of top quark production and prominent searches for the Higgs boson. We measure a b-jet cross section of 2.74+/-0.27(stat)+/-0.42(syst) pb in association with a single flavor of leptonic W boson decay over a limited kinematic phase space. This measured result cannot be accommodated in several available theoretical predictions.

16.
Phys Rev Lett ; 104(14): 141801, 2010 Apr 09.
Artigo em Inglês | MEDLINE | ID: mdl-20481931

RESUMO

We report on a search for the standard model Higgs boson produced in association with a W or Z boson in pp collisions at square root(s)=1.96 TeV recorded by the CDF II experiment at the Tevatron in a data sample corresponding to an integrated luminosity of 2.1 fb(-1). We consider events which have no identified charged leptons, an imbalance in transverse momentum, and two or three jets where at least one jet is consistent with originating from the decay of a b hadron. We find good agreement between data and background predictions. We place 95% confidence level upper limits on the production cross section for several Higgs boson masses ranging from 110 GeV/c(2) to 150 GeV/c(2). For a mass of 115 GeV/c(2) the observed (expected) limit is 6.9 (5.6) times the standard model prediction.

17.
Phys Rev Lett ; 104(1): 011801, 2010 Jan 08.
Artigo em Inglês | MEDLINE | ID: mdl-20366357

RESUMO

We present the results of a search for supersymmetry with gauge-mediated breaking and chi(1)(0) --> gammaG in the gammagamma + missing transverse energy final state. In 2.6+/-0.2 fb(-1) of pp collisions at square root(s) = 1.96 TeV recorded by the CDF II detector we observe no candidate events, consistent with a standard model background expectation of 1.4+/-0.4 events. We set limits on the cross section at the 95% C.L. and place the world's best limit of 149 GeV/c2 on the chi(1)(0) mass at tau(chi(1)(0)) << 1 ns. We also exclude regions in the chi(1)(0) mass-lifetime plane for tau(chi(1)(0)) approximately < 2 ns.

18.
Phys Rev Lett ; 104(10): 101801, 2010 Mar 12.
Artigo em Inglês | MEDLINE | ID: mdl-20366413

RESUMO

We report two complementary measurements of the WW + WZ cross section in the final state consisting of an electron or muon, missing transverse energy, and jets, performed using pp collision data at square root of s = 1.96 TeV collected by the CDF II detector. The first method uses the dijet invariant mass distribution while the second more sensitive method uses matrix-element calculations. The result from the second method has a signal significance of 5.4sigma and is the first observation of WW + WZ production using this signature. Combining the results gives sigma(WW + WZ) = 16.0 +/- 3.3 pb, in agreement with the standard model prediction.

19.
Phys Rev Lett ; 104(10): 102002, 2010 Mar 12.
Artigo em Inglês | MEDLINE | ID: mdl-20366415

RESUMO

We report a measurement of the lifetime of the Lambda(b)(0) baryon in decays to the Lambda(c)(+)pi(-) final state in a sample corresponding to 1.1 fb(-1) collected in pp collisions at square root of s = 1.96 TeV by the CDF II detector at the Tevatron collider. Using a sample of about 3000 fully reconstructed Lambda(b)(0) events we measure tau(Lambda(b)(0)) = 1.401 +/- 0.046(stat) +/- 0.035(syst) ps (corresponding to ctau(Lambda(b)(0)) = 420.1 +/- 13.7(stat) +/- 10.6(syst) microm, where c is the speed of light). The ratio of this result and the world average B(0) lifetime yields tau(Lambda(b)(0))/tau(B(0)) = 0.918 +/- 0.038 (stat) and (syst), in good agreement with recent theoretical predictions.

20.
Phys Rev Lett ; 104(11): 111802, 2010 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-20366464

RESUMO

We present a search for the technicolor particles rho{T} and pi_{T} in the process pp-->rho{T}-->Wpi{T} at a center of mass energy of sqrt[s]=1.96 TeV. The search uses a data sample corresponding to approximately 1.9 fb{-1} of integrated luminosity accumulated by the CDF II detector at the Fermilab Tevatron. The event signature we consider is W-->lnu and pi{T}-->bb, bc or bu depending on the pi{T} charge. We select events with a single high-p{T} electron or muon, large missing transverse energy, and two jets. Jets corresponding to bottom quarks are identified with multiple b-tagging algorithms. The observed number of events and the invariant mass distributions are consistent with the standard model background expectations, and we exclude a region at 95% confidence level in the rho{T}-pi{T} mass plane. As a result, a large fraction of the region m(rho{T})=180-250 GeV/c{2} and m(pi{T})=95-145 GeV/c{2} is excluded.

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