1.
RSC Adv
; 12(43): 28207-28216, 2022 Sep 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36320230
RESUMO
The Galß(1â4)Man disaccharide, found in the cell surface lipophosphoglycan (LPG) of Leishmania species, has been synthesized by a Ferrier glycosylation/cis-dihydroxylation strategy. This stereoselective method proved efficient for synthesizing the target saccharide in good yield. In addition, we prepared two clickable O-glycoside and phospho-glycoside versions of Galß(1â4)Man to enable conjugation to protein carriers for further immunological and antibody-binding studies.