Changes in Oxygen Saturation During Fiberoptic Bronchoscopy: High-Flow Nasal Cannula versus Standard Oxygen Therapy.

BACKGROUND: Hypoxemia is a relatively common complication in stable patients during fiberoptic bronchoscopy (FOB). To prevent this complication, high-flow nasal cannula (HFNC) has been described as an alternative to standard oxygen therapy. However, the advantages of HFNC over standard oxygen therapy in acute care patients receiving supplemental oxygen before FOB performed with an oral approach are unknown. METHODS: We conducted an observational study that involved subjects with a presumptive diagnosis of pneumonia and a clinical indication for a bronchial aspirate sample. The type of oxygen support (standard oxygen therapy vs HFNC) was selected according to availability. The oxygen flow in the HFNC group was 60 L/min. In both groups, the FIO2 was set at 0.40. Hemodynamic, respiratory dynamics, and gas exchange data were collected at baseline, before, during, and 24 h after FOB. RESULTS: Forty subjects were included, 20 in each group (HFNC and standard oxygen therapy). The study was performed on day 5 of hospitalization in the HFNC group and on day 4 in the standard oxygen therapy group (P = .10). No significant between-group differences in baseline characteristics were observed. HFNC vs standard oxygen therapy was associated with a smaller decrease in SpO2 levels during the procedure (94% vs 90%; P = .040, respectively) and with less variation between the last SpO2 measured before FOB and the lowest SpO2 during FOB (Δ SpO2 ): 2% versus 4.5% (P = .01, respectively). CONCLUSIONS: In acute subjects who required oxygen support before FOB, the use of HFNC during FOB with an oral approach was associated with a smaller decrease in SpO2 and lower Δ SpO2 compared with standard oxygen therapy.

Educational open source kit for the evaluation of acoustic leaky wave antennas with metamaterials.

There is a growing interest in the field of acoustic metamaterials. These materials use periodic structures to exhibit properties not usually found in nature, such as negative mass or negative compressibility. The physics supporting these devices might seem counterintuitive at first, necessitating additional educational resources in this area. A leaky wave antenna (LWA) is a good example of a practical device that can be implemented as a standard material and a metamaterial. As the latter, the device extends its operational range, linking concepts related to both versions. This work presents an experimental open source kit designed for teaching the basic notions, including a computational routine for testing its analytical performance. The kit shown in this work has interchangeable units to experiment with several configurations (slit, axisymmetric, periodic hole, and membrane based metamaterial) and parameters of the antenna's design. The kit provides an opportunity to get hands-on experience on the real-life performance of LWAs, thanks to the use of low-cost materials, minimal equipment, and the practical nature of the antenna.