Three-dimensional evaluation of mandibular condyle and coronoid process according to sex, age, and skeletal deformities.

OBJECTIVE: To correlate the volume of the mandibular condyle (MC) and the coronoid process (CP) with sex, age, and skeletal deformities. METHODS: The structures were visualized through semi-automatic segmentation of the 3D model and complemented with manual segmentation, using the ITK-SNAP 3.0 software. Mann-Whitney, Kruskal-Wallis, and the Dunn test were performed (p < 0.05). RESULTS: The MC volume showed statistical differences between sex and skeletal deformities. Men and Class III patients showed higher values. CP volume was not influenced by age or skeletal deformities. However, statistical differences were found between sex, with higher values for men. CONCLUSION: MC volume was influenced by sex and skeletal deformities, while CP was influenced only by sex. Women have smaller volumes for these structures. Age is not correlated with the volume of MC and CP. The highest and lowest values of condylar volume were found for Class III and II individuals, respectively.

Accuracy of three-dimensional soft tissue profile prediction in orthognathic surgery.

PURPOSE: To evaluate the accuracy of three-dimensional (3D) soft tissue prediction in bimaxillary orthognathic surgery. METHODS: Cone-beam computed tomographs of 88 patients with class II (n = 46) and class III (n = 42) malocclusions, who underwent bimaxillary orthognathic surgery, were included in this retrospective study. 3D soft tissue prediction and postoperative outcome were compared by using ten landmarks of facial soft tissues. Patients' sex and age were also assessed. Results were analyzed using a mixed model methodology (p < 0.05). RESULTS: The success criterion adopted was a mean discrepancy of < 2 mm. Most mandibular landmarks indicated a tendency for underprediction with a downward direction in class II patients, with some values > 2 mm. In class III, there was overprediction with a downward direction for the mandibular landmarks, with values < 2 mm. More accurate results were found in female and older patients. CONCLUSIONS: 3D surgical planning showed clinically acceptable results for predicting soft tissues in patients undergoing bimaxillary orthognathic surgery, with more accurate results for class III patients. Although some differences were found when age and sex were interacted, a consistent association between these variables could not be stated. These results support the clinician, as accuracy can provide a strong guide to the surgeon when planning surgical orthodontic treatment.

Correlation between the presence of the median perforating canal in adults with sex, age and skeletal facial patterns: A cross-sectional study.

INTRODUCTION: The aim of the present study was to evaluate the presence of the median perforating canal (MPC) and its morphometric measurements in Cone Beam CT (CBCT) scans of adult patients, correlating the findings with sex, age and skeletal facial patterns. MATERIAL AND METHODS: 717 CBCT scans were selected from a Brazilian population and the presence of the MPC was recorded. MPC diameter was measured in three points: lingual, medial and buccal. To determine the correlation between MPC presence and sex, age and ANB angle classifications the Chi-square test was performed. MPC diameters were related to sex, age and skeletal discrepancies using Mann-Whitney U and Kruskal-Wallis tests. The level of significance adopted was 5%. RESULTS: Of the 717 CBCT scans analyzed, the MPC was present in 181 patients (25.24%), 279 (38.91%) men and 438 (61.09%) women. The mean age was 37.91 (±14.46) years old, ranging from 18 to 88 years old. There were no differences in the presence of MPC between women and men (p = 0.85), between skeletal discrepancies (p = 0.09) and age groups (p = 0.94). Regarding the MPC diameter, statistical difference was found only for the medial diameter between sexes (p = 0.04), with the highest values in men. CONCLUSION: The MPC was detected in 25.24% of the studied population, with significant differences only for its medial diameter in men.

Differential diagnosis for an unusual calcification in the maxillary sinus: case report / Diagnóstico diferencial para calcificação incomum em seio maxilar: relato de caso

ABSTRACT The aim of this study was to report a rare case of an asymptomatic calcification of unusual size and shape, inside the maxillary sinus identified on a cone beam computed tomography exam and to discuss the importance of knowledge of the anatomy of maxillary sinus and its changes carefully evaluating the entire volume of the images, regardless of the region of interest. An 83-year-old female patient underwent a cone beam computed tomography exam for other diagnostic purposes in the maxillofacial region. When analyzing the entire volume, an image of unusual limits, hyperdense and calcified was found in the right maxillary sinus, close to the anterior and medial wall, with a rounded and homogeneous shape, occupying approximately one third of the maxillary sinus. There was no lytic or erosive lesions on the maxillary sinus wall. The main diagnostic hypotheses raised were giant anthrolith, mucous retention phenomenon and osteoma. Due to the anatomical complexity of the maxillary sinus, diagnosis in this region becomes a challenge. Considering the limitations of 2D exams, the cone beam computed tomography exam can be used to evaluate these structures. Knowledge of differential hypotheses is extremely important for the case to be conducted correctly, but it does not replace biopsy and histopathological examination.

RESUMO O objetivo desse estudo foi relatar um caso raro de uma calcificação assintomática de tamanho e formato incomum, no interior do seio maxilar, diagnosticado em um exame de tomografia computadorizada de feixe cônico, além de discutir a importância do conhecimento da anatomia do seio maxilar e suas alterações, avaliando cuidadosamente todo o volume das imagens, independentemente da região de interesse. Paciente do sexo feminino, 83 anos de idade, realizou uma tomografia computadorizada de feixe cônico para outros fins de diagnóstico na região bucomaxilofacial. Ao analisar todo volume da tomografia encontrou-se uma imagem de limites incomuns, hiperdensa e calcificada, no seio maxilar direito, próximo a parede anterior e medial, com formato arredondado e homogêneo, ocupando aproximadamente um terço do seio maxilar, com as suas paredes intactas e sem nenhuma lesão lítica ou erosiva. As principais hipóteses diagnosticas levantadas foram antrólito gigante, fenômeno de retenção mucoso e osteoma. Devido a complexidade anatômica do seio maxilar, o diagnóstico nessa região se torna um desafio. Considerando as limitações dos exames 2D, a tomografia computadorizada de feixe cônico pode ser empregada para a avaliação dessas estruturas. O conhecimento do raciocínio diagnóstico e das hipóteses diferenciais são de extrema importância para o que o caso seja conduzido corretamente, porém não substituem a biópsia e o exame histopatológico.

Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life

ABSTRACT: The aim of this study is to report the results obtained with a protocol of topical application of capsaicin gel 0.025 % in the management of burning mouth syndrome (BMS) to evaluate the influence of the disease and treatment on their quality of life (QOL) using the OHIP-14 questionnaire (Oral Health Impact Profile). After clinical examination and diagnosis of BMS, 10 patients reported the intensity of the burning by means of a subjective score ranging from 0 to 10 and also answered the OHIP-14. Then, a topical application protocol of capsaicin gel 0.025 % was initiated, with weaning from medication and complete withdrawal within 180 days. At each reassessment consultation (30, 60, 90 and 180 days), the patients answered the OHIP-14 and subjective burning scores were collected again. Overall, the capsaicin gel showed gradual reduction or elimination of symptoms of BMS, as well as an improvement in the QOL of patients throughout treatment. At 180 days, after medication withdrawal, 6 patients (60 %) reported total absence of burning and in four patients (40 %) the score remained or decreased. In one patient (10 %) the score increased, although it remained below the initial score. The results showed an improvement in the QOL of all patients who completed the protocol and the impact of BMS on the QOL decreased in relation to the initial score in all patients. The topical use of 0.025 % capsaicin gel was effective in reducing or remitting symptoms of BMS. The OHIP-14 questionnaire showed the negative impact of BMS on patients' QOL and the role of treatment in its improvement.

RESUMEN: El objetivo de este estudio fue reportar los resultados obtenidos con un protocolo de aplicación tópica de gel de capsaicina al 0,025 % en el manejo del síndrome de boca ardiente (SBA), para evaluar la influencia de la enfermedad y el tratamiento en su calidad de vida (CV) mediante el cuestionario OHIP-14. Tras el examen clínico y diagnóstico de SBA, 10 pacientes refirieron la intensidad del ardor mediante una puntuación subjetiva de 0 a 10 y también respondieron la OHIP-14. Luego, se inició un protocolo de aplicación tópica de gel de capsaicina al 0,025%, con destete de la medicación y retiro completo en 180 días. En cada consulta de reevaluación (30, 60, 90 y 180 días), los pacientes respondieron el OHIP-14 y se recogieron nuevamente las puntuaciones subjetivas de quemado. En general, el gel de capsaicina mostró una reducción o eliminación gradual de los síntomas del SBA, así como una mejora en la calidad de vida de los pacientes durante todo el tratamiento. A los 180 días, después de la retirada de la medicación, 6 pacientes (60 %) informaron ausencia total de ardor y en cuatro pacientes (40%) la puntuación se mantuvo o disminuyó. En un paciente (10 %) la puntuación aumentó, aunque se mantuvo por debajo de la puntuación inicial. Los resultados mostraron una mejora en la CV de todos los pacientes que completaron el protocolo y el impacto de SBA en la CV disminuyó en relación con la puntuación inicial en todos los pacientes. El uso tópico de gel de capsaicina al 0,025 % fue efectivo para reducir o remitir los síntomas del SBA. El cuestionario OHIP-14 mostró el impacto negativo de SBA en la CV de los pacientes y el papel del tratamiento en su mejora.

Accuracy of cone-beam CT in detecting vertical root fractures in teeth with post-endodontic restorations: an in vitro study

The aim of this study was to evaluate the accuracy of cone-beam CT (CBCT) for the detection of artificially created vertical root fractures (VRF) in extracted teeth restored with metallic (MP) and fiberglass (FGP) posts. After root canal obturation, 60 extracted human premolars were scanned by using the highest-resolution settings of a CBCT unit. Theprepared roots were randomly divided into three groups: group C (control group): non-restored and non-endodontically treated teeth (n = 20); group MP (n = 20); group FGP (n = 20). In all groups, 10 teeth were artificially fractured. Two external and independent observers blindly recorded the presence or absence of VRF. Sensitivity, specificity, accuracy, intra-and interobserver agreement were calculated. Kappa value for inter-and intraobserver agreement was 0.82 and 0.84 respectively, demonstrating goodagreement. The highest values for sensitivity (0.80 -0.90), specificity (1.00) and accuracy (0.90 -0.95) were found in the control group. The teeth with FGP restoration presented the lowest sensitivity (0.30 -0.50) and accuracy (0.60 -0.65) values. Both examiners had a good performance in the diagnosis of fractures in teeth with MP, with accuracy ranging between 0.85 -0.90. The presence of MP did not influence accuracy; however, the presence of FGP reduced the diagnostic capacity of CBCT.

Imaginology Tridimensional Study of Temporomandibular Joint Osseous Components According to Sagittal Skeletal Relationship, Sex, and Age.

OBJECTIVE: To assess the temporomandibular joint (TMJ) osseous components morphology and the condyle position in patients with different sagittal skeletal relationships, sex, and age, using cone-beam computed tomography (CBCT). METHODS: The CBCT images of 180 asymptomatic patients (60 class I, 60 class II, and 60 class III) were assessed retrospectively. Groups were also divided according to age (<40 years, n = 90; ≥40 years, n = 90) and sex (male, n = 90; female, n = 90). Right- and left-sided TMJ spaces, articular eminence inclination (AEI) and height (AEH), thickness of the roof of the glenoid fossa (TRGF) and the anteroposterior position of the condyle in glenoid fossa were evaluated. Differences were tested using the analysis of variance, Tukey and t-tests (P < 0.05). RESULTS: For condylar position, no differences were found between sex and age groups, but spatial differences existed among skeletal classes. Significant differences were found between the right and left angular position in patients with malocclusion. Class II individuals presented lower anterior articular spaces. The condyle-glenoid fossa relationship presented a moderate correlation of bilaterality. The AEI and AEH were significant lower in class III individuals and class I patients presented the lowest values for TRGF. The values of AEH, TRGF and of all joint spaces of males were higher. In individuals over the age of 40 years, the AEI and AEH measurements were significant greater. CONCLUSION: Sagittal skeletal relationships have a significant effect on condyle position, AEI, and AEH. The eminence inclination and height and TRGF are influenced by sex and age.

Accuracy of two-dimensional pharyngeal airway space prediction for bimaxillary orthognathic surgery.

PURPOSE: The aim of this retrospective study was to evaluate the accuracy of two-dimensional (2D) virtual surgical planning (VSP) of pharyngeal airway space (PAS) in patients submitted to bimaxillary orthognathic surgery. METHODS: This study was conducted with lateral cephalograms acquired through cone-beam computed tomography records of 33 patients, divided into group 1-patients submitted to maxillary advancement and mandibular setback (n = 17) and group 2-patients submitted to maxillomandibular advancement (n = 16). Records were taken 1 to 2 months prior to surgery, which was used to perform the 2D VSP (Tp), and 6 to 8 months after surgery (T1). In Dolphin Imaging software, the anteroposterior size of the PAS was calculated at the level of four craniometric points: A, occlusal plane (Mx), B, and pogonion (Pog). Two previously calibrated examiners performed these measurements. Statistical analyses were conducted using Kendall and t tests at a 5% level of significance. RESULTS: There was a concordance between the two examiners at all points and times. In group 1, points A and B have statistically significant differences between the PAS measurements performed in Tp and T1, while in group 2, none of the PAS points showed statistically significant differences when comparing Tp to T1. CONCLUSIONS: 2D computer-based cephalometric prediction in Dolphin Imaging software offers a good orientation to professionals during the surgical procedure of bimaxillary surgeries since its use is considered clinically relevant in daily practice.

Accuracy in the diagnosis of vertical root fractures, external root resorptions, and root perforations using cone-beam computed tomography with different voxel sizes of acquisition.

AIM: The aim of this study is to assess the accuracy of images acquired with cone-beam computed tomography (CBCT) in the identification of three different root alterations. MATERIALS AND METHODS: Forty human premolars were allocated to four experimental groups (n = 10): sound teeth (control), vertical root fracture (VRF), external root resorption (ERR), and root perforation (RP). After the root alterations had been produced, four teeth were randomly assembled into 10 macerated mandibles and submitted to CBCT. Images were acquired with five voxel sizes (0.125, 0.200, 0.250, 0.300, and 0.400 mm) and assessed by three experienced dental radiologists. Sensitivity, specificity, positive and negative predictive values, and the areas under the receiver operating characteristic curve (accuracy) were calculated. The accuracy of imaging in different voxel sizes was compared with Tukey exact binomial test (α=5%). RESULTS: Accuracy with voxel sizes 0.125, 0.200, and 0.250 mm was significantly higher in the detection of ERRs and VRFs than voxel sizes 0.300 and 0.400 mm. No statistical difference was found in terms of accuracy among any of the studied voxel sizes in the identification of RPs. CONCLUSIONS: Voxel size 0.125 mm produced images with the best resolution without increasing radiation levels to the patient when compared to voxel sizes 0.200 and 0.250 mm. Voxel sizes 0.300 and 0.400 mm should be avoided in the identification of root alterations.

Golden Proportion Analysis of Dental-Skeletal Patterns of Class II and III Patients Pre and Post Orthodontic-orthognathic Treatment.

INTRODUCTION: The golden proportion has been used in dentistry in an attempt to improve facial function and, possibly, esthetics by simplifying the diagnosis of facial and dental disharmony. The aim of this study is to analyze pre- and postoperative cephalometric tracings of lateral cephalograms of patients with class II and III deformities submitted to orthognathic surgery, and verify if the 13 dental-skeletal patterns (ratios), as defined by Ricketts, moved closer to or further away from the golden proportion. MATERIALS AND METHODS: A total of 110 lateral cephalometric radiographs, 55 obtained preoperatively and 55 postoperatively, were analyzed using Dolphin Imaging software. RESULTS: Radiographs analysis demonstrated that ratios 1, 3, 4, 5, 7, 8, 9, 10, and 13 remained statistically different from the golden proportion postoperatively. Ratio 12 was the only one to move closer to the golden number, while the opposite happened with ratio 6, which moved further away after the surgery. Ratios 2 and 11 kept statistically similar to the golden proportion both pre and postoperatively. CONCLUSION: It may be concluded that orthognathic surgery had little effect on the proportions studied, and that the golden proportion was not present in the majority of the ratios analyzed neither before nor after surgery. CLINICAL SIGNIFICANCE: Determine whether the facial patterns approach the golden ratio after surgical correction. Also determine whether the golden ratio may be a standard to guide the surgical treatment of patients with skeletal patterns of type II and III.

Treatments and supportive therapies for oral manifestations of chronic graft-versus-host disease / Tratamentos e terapias de suporte para manifestações orais da doença crônica do enxerto contra hospedeiro

The aim of this study was to conduct a systematic review of treatments and therapies for oral manifestations of chronic graft-versus-host disease, aiming at improving patients' quality of life and mainly the reduction of mortality caused by graft- versus-host disease. A systematic review was carried out by two evaluators, a Dentistry professor and an undergraduate student. A selection of open-access full-text online articles, carried out on PubMed, GoPubmed, NLM Gateway, LILACS, BIREME, SciELO, IBECS, and Web of Science. The survey was completed in July 2012. Of the 1147 studies found, 52 fit the selection criteria. Patients (n = 2130) received different treatment regimens, either systemic or topical. Drugs for systemic therapy were divided into those with action on the inhibition of proliferation and/or release of T and B cells, with action on inflammatory disorders, and of immunomodulatory effect. Topical drugs were divided into their pattern of mucosal absorption and their ability to act on tissue growth factors. The analysis of articles concluded that the most used systemic drugs were Methylprednisolone and corticosteroids, and Tacrolimus and topical Cyclosporine for topical and local therapy.

O objetivo do trabalho foi realizar uma revisão sistemática sobre tratamentos e terapias de suporte para manifestações orais da doença crônica do enxerto contra hospedeiro, visando à melhoria da qualidade de vida dos pacientes e, principalmente, a redução da mortalidade causada pela doença do enxerto contra hospedeiro. A revisão sistemática foi realizada por dois examinadores, um professor e um graduando de odontologia. A seleção de acesso aberto de artigos online de texto completo, realizadas no PubMed, GoPubmed, NLM Gateway, LILACS, BIREME, SciELO, IBECS e Web of Service. A revisão foi concluída em julho de 2012. Dos 1.147 estudos encontrados, 52 se enquadraram nos critérios de seleção. Os pacientes (n = 2130) receberam diferentes tratamentos, seja de forma sistêmica ou tópica. Os medicamentos para tratamento sistêmico foram divididos entre aqueles com ação na inibição da proliferação e / ou liberação de células T e B, com ação em doenças inflamatórias, e de efeito imunomodulador. Drogas tópicas foram divididas em seu padrão de absorção da mucosa e a sua capacidade para atuar sobre os fatores de crescimento de tecidos. A análise dos artigos permitiu concluir que os medicamentos sistêmicos mais utilizados foram Metilprednisolona e corticosteróides, e Tacrolimus e Ciclosporina tópica para a terapia tópica e local.

Solitary bone cyst: an analysis of 12 cases / Cisto ósseo solitário: uma análise de 12 casos

Apresentar informações adicionais sobre o COS a partir da revisão de 12 casos, com a descrição das características clínicas e radiográficas, comparando-as com a literatura recente. Realizou-se um estudo retrospectivo observacional de casos de COSs apresentados por pacientes do projeto de extensão: 'Diagnóstico, tratamento e epidemiologia das doenças da cavidade bucal ­ Lebu', da Universidade Estadual de Maringá ­ Paraná, Brasil, entre os anos de 1995 e 2014. Dos 2.424 prontuários de pacientes que foram submetidos a diferentes tipos de biópsia, 12 casos de COS foram encontrados e selecionados para pesquisa. Todos os casos ocorreram na mandíbula, preferencialmente em pacientes jovens na segunda década de vida. Ocasionalmente, a expansão da tábua óssea cortical foi notada e, por meio de exame histopatológico, o diagnóstico da lesão foi confirmado. A maioria dos COS são, geralmente, assintomáticos e diagnosticados por acaso em exames radiográficos de rotina. No entanto, o COS pode causar expansão óssea ou rompimento de cortical óssea, visível apenas com métodos de imagem mais sofisticados. O presente trabalho de pesquisa mostrou que o diagnóstico de COS é beneficiado pelo uso da radiografia convencional e tomografia computadorizada, associada a exames clínicos cuidadosos.

To present further information about SBCs based on a retrospective study of 12 cases, by describing their clinical and radiographic characteristics, and comparing them with recent findings. The study examined SBCs from the Projeto Lesões Bucais 'treatment and epidemiology of diseases of the oral cavity', run at State University of Maringá, Paraná State, Brazil, between 1995 and 2014. Twelve cases were found among the records of 2.424 patients who had been submitted to different types of biopsy. All cases occurred in the mandible, predominantly in patients in the second decade of life, in the region posterior to canines, and among women. All lesions were solitary, 75% of them unilocular. Helicoidal CT showed expansion and rupture of the cortical bone in one case. Differential diagnosis was confirmed by means of histopathological examination. Treatment consisted of surgical exploration in all cases. Most SBCs are usually asymptomatic and diagnosed by chance on routine X-ray examination. However, SBC can cause bone expansion or bone rupture, only visible with more sophisticated imaging systems. This study showed that the diagnosis of SBC benefits with the use of conventional radiography and CT, associated with careful clinical examinations.

Influence of Image Filters and Variation in Horizontal Angle of Incidence of X-ray Beam in Digital Interproximal Radiographs for Diagnosis of Secondary Caries in Esthetic Restorations.

BACKGROUND: Secondary or recurrent caries are located around restoration margins or under these lesions, and can lead to tooth loss. The interproximal or bite wing radiograph is the technique of choice to assist diagnosis of secondary caries. OBJECTIVE: To evaluate diagnostic accuracy of secondary caries in pulpal walls artificially created in extracted human premolars, observed in digital bitewing radiographs using variations in horizontal X-ray beam angle of incidence and application of enhancement filters. MATERIALS AND METHODS: The sample consisted of 20 healthy premolars, in which secondary caries lesions were simulated by means of subjecting the pulpal wall of the cavity to wear with spherical carbide drill half, fitted to a high speed handpiece, under constant cooling, focused perpendicular to the tooth surface. The orifices were filled with wax and all teeth were restored with composite resin Filtek Z350 XT(®). Later teeth were radiographed with a digital sensor complementary metal-oxide-semiconductor (CMOS) varying the horizontal angle at intervals of 2°, covering a range of -10 to +10°. RESULTS: The results showed that in the diagnosis of secondary caries, there was no statistically significant difference between the 2 pseudocolor filters, and negative and direct digital radiography. The pseudocolor filter no. 1 showed statistically significant differences, except at a horizontal angle of 0°, thus indicating lower efficiency in the diagnosis of secondary caries. CONCLUSION: Secondary caries with esthetic pulp wall restoration can be diagnosed irrespective of variation in the horizontal angle of incidence of the X-ray beam. The use of different radiographic enhancement filters did not result in improved diagnosis of secondary caries.

Comparison of diagnostic accuracy of root perforation, external resorption and fractures using cone-beam computed tomography, panoramic radiography and conventional & digital periapical radiography.

CONTEXT: Some radicular changes are challenging for clinicians to diagnose, such as of root perforations, external root resorption (ERR), and vertical root fractures (VRFs). This study aims to facilitate it by comparing the diagnostic accuracy of cone-beam computed tomography (CBCT), orthopantomography, and conventional and digital periapical radiography (DPR) in the diagnosis of such problems. Is it worth doing CBCT despite the radiation dose? AIMS: To evaluate and compare the diagnostic accuracy of CBCT, panoramic radiography, and conventional and DPR in the diagnosis of root perforation (RP), ERR, and VRF. MATERIALS AND METHODS: The sample consisted of 40 extracted human teeth and 10 macerated human mandibles. RPs were performed using diamond burs, ERRs using spherical carbide burs, and RFs using a universal machine EMIC-DL 1000. The images were evaluated by 6 dentomaxillofacial radiologists. RESULTS: Receiver operating characteristic (ROC) revealed that CBCT showed the highest area under the ROC curve (Az) values for RP, ERR, and VRF (0.903, 0.950, and 0.849, respectively). The worst Az values for RP, ERR, and VRF (0.718, 0.494, and 0.611, respectively) were for panoramic radiography. CONCLUSIONS: CBCT showed the best results in the diagnosis of ERR and VRF. The diagnosis of ERR was the least accurate, panoramic radiography being not appropriate for its diagnosis. CBCT and conventional periapical radiography obtained similar results for the evaluation of RP. So for, RP indicate the conventional periapical radiography because CBCT has a higher radiation dose.

Prevalência de neoplasias bucais malignas em Maringá/PR / Prevalence of oral malignant neoplasms at Maringá/PR

As neoplasias malignas são patologias agressivas, que possuem taxas elevadas de incidência e mortalidade. O câncer bucal representa a sétima posição no ranking das neoplasias malignas mais encontradas no homem. Sobre isso, o presente artigo tem por finalidade determinar a prevalência de neoplasia maligna nos projetos de extensão de lesões bucais da Universidade Estadual de Maringá e apresentar o trabalho multiprofissional de atenção à saúde bucal desenvolvido, mostrando a importância do tratamento integrado do paciente com câncer bucal. Os resultados do levantamento epidemiológico evidenciaram que a maioria dos pacientes acometidos pertencia ao gênero masculino (n=76), com idade entre a quarta e a quinta década de vida. A região mais acometida é o lábio inferior (18,7%), e a lesão diagnosticada histopatologicamente mais prevalente é o carcinoma epidermoide (76%). Portanto, o que se observa é que combater o câncer de boca ainda é um grande desafio para as Universidades responsáveis pela formação dos profissionais de saúde, para o sistema público de saúde e para a população. Além disso, a integração multiprofissional de atenção a esse paciente é muito deficiente e difícil, frente à complexidade dos casos.

Malignant neoplasms are aggressive pathologies that have high rates of incidence and mortality. The oral cancer represents the seventh position in the ranking of the most frequent malignancies in humans. This article aims to determine the prevalence of malignancy in the extension projects of oral lesions of the State University of Maringá and present the work of multidisciplinary oral health care developed by the same, showing the importance of integrated treatment of the patient with oral cancer. The results of epidemiological survey showed that the majority of patients are male (n=76), aged between fourth and fifth decades of life, the most affected region is the lower lip (18,7%) the diagnosed histopathologically squamous cell carcinoma (76%) more prevalent. So, what is observed that, to combat oral cancer, remains a major challenge for the universities responsible for training health professionals for the public health system and population, in addition, the integration of multiprofessional attention to this patient is very deficient and difficult, compared to the complexity of cases.

Effect of gamma rays on the bone repair process in rats with estrogen deficiency.

This study aimed at evaluating the bone repair process in ovariectomized rats submitted to an irradiation procedure. For this purpose, one hundred rats were randomly divided in four experimental groups: control, ovariectomized, irradiated and irradiated/ovariectomized. A bone defect was made on all animals' tibias. Three days after surgery, only irradiated and irradiated/ovariectomized rats received 8 Gy of gamma rays on the lower limbs region. The animals were sacrificed 7, 14, 21 and 28 days after surgery in order to assess the repair process. It was possible to observe a delay in the bone repair process in the irradiated/ovariectomized group, in which there was a remarkable association between estrogen deficiency and ionizing radiation resulting in the reduction of newly formed bone production, thus accelerating the resorption process.

Effect of gamma rays on the bone repair process in rats with estrogen deficiency

This study aimed at evaluating the bone repair process in ovariectomized rats submitted to an irradiation procedure. For this purpose, one hundred rats were randomly divided in four experimental groups: control, ovariectomized, irradiated and irradiated/ovariectomized. A bone defect was made on all animals' tibias. Three days after surgery, only irradiated and irradiated/ovariectomized rats received 8 Gy of gamma rays on the lower limbs region. The animals were sacrificed 7, 14, 21 and 28 days after surgery in order to assess the repair process. It was possible to observe a delay in the bone repair process in the irradiated/ovariectomized group, in which there was a remarkable association between estrogen deficiency and ionizing radiation resulting in the reduction of newly formed bone production, thus accelerating the resorption process.

O objetivo deste trabalho foi avaliar o processo de reparo ósseo em ratas ovariectomizadas submetidas ao procedimento de irradiação. Para isto, cem ratas foram aleatoriamente divididas em quatro grupos experimentais: controle, ovariectomizado, irradiado e ovariectomizado/irradiado. Um defeito ósseo foi confeccionado nas tíbias de todos os animais. Três dias após a cirurgia, apenas os animais pertencentes aos grupos irradiado e ovariectomizado/irradiado receberam 8 Gy de radiação gama na região dos membros inferiores. Os animais foram sacrificados 7, 14, 21 e 28 dias após a cirurgia. Foi possível observar um atraso no processo de reparo ósseo nos animais do grupo ovariectomizado/irradiado, no qual houve uma marcante associação entre deficiência de estrógeno e radiação ionizante, resultando na redução da produção de osso neoformado, acelerando o processo de reabsorção.

Miíase humana bucal por cochliomyia hominivorax (Coquerel, 1858) em Nova Esperança, estado do Paraná, Brasil / Human oral myiasis by cochliomyia hominivorax (Coquerel, 1858) in Nova Esperança, Paraná state, Brazil

Miiases são infestações de tecidos vivos ou necrosados por larvas de dípteros, da subordem dos ciclorrafos (moscas). Embora consideradas raras, as miíases humanas têm sido descritas no norte, no centro e no sul da América. Neste trabalho, os autores apresentam o relato de um caso de miíase oral por Cochilio,yia hominivorax, cuja patologia em cavidade bucal foi pouco relatada

Aspectos de relevantes importância na seleçäo de um sistema radiográfico digital / Aspects of relevant importance in the selection of a digital radiographic system

O presente trabalho foi desenvolvido com o propósito de fornecer subsídios aos profissionais que desejam adquirir um sistema radiográfico digital, abordando aspectos de relevante importância na seleçäo adequada desse tipo de equipamento, os quais, se observados, podem prevenir futuros dissabores após a aquisiçäo dos sistemas