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1.
J Toxicol Environ Health A ; 82(12): 697-701, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31307340

RESUMO

The aim of this study was to identify factors associated with an increased exposure to arsenic-contaminated soil in a Kentucky neighborhood as part of collaborative public health response. An exposure assessment survey was administered to residents and toenail clippings and soil samples analyzed for arsenic concentration. The associations between exposure variables and arsenic concentrations were evaluated using a multivariate-generalized estimating equation. An ecological assessment of cancer incidence in the community was also conducted using standardized incidence ratio maps. Median toenail arsenic was 0.48 micrograms/gram (µg/g), twice the expected regional level of 0.2 µg/g. Mean residence surface soil arsenic level was 64.8 ppm. An increase of 1 ppm of residence concentration was significantly associated with a 0.003 µg/g rise in toenail levels. Concentrations for respondents who engaged in digging were 0.68 µg/g significantly higher compared to individuals who did not. No significantly elevated rates of lung or bladder cancer were observed in the affected ZIP codes. Living in areas with high soil arsenic contamination might lead to (1) increased exposure; (2) elevated residence soil arsenic concentrations and (3) the action of digging in the soil was associated with elevated toenail arsenic levels. Based upon elevated soil levels identified, residents were recommended to move from the contaminated environment until remediation was complete. Additional recommendations included regular health-care follow-up.


Assuntos
Arsênio/química , Monitoramento Ambiental , Poluentes do Solo/química , Adolescente , Adulto , Criança , Humanos , Kentucky , Unhas/química , Características de Residência , Adulto Jovem
2.
Vaccine ; 30(2): 317-21, 2012 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-22085555

RESUMO

BACKGROUND: Refugees are highly vulnerable populations with limited access to health care services. The United States accepts 50,000-75,000 refugees for resettlement annually. Despite residing in camps and other locations where vaccine-preventable disease outbreaks, such as measles, occur frequently, refugees are not required to have any vaccinations before they arrive in the United States. PURPOSE: We estimated the medical and public-health response costs of a case of measles imported into Kentucky by a refugee. METHODS: The Kentucky Refugee Health Coordinator recorded the time and labor of local, state, and some federal personnel involved in caring for the refugee and implementing the public health response activities. Secondary sources were used to estimate the labor and medical care costs of the event. RESULTS: The total costs to conduct the response to the disease event were approximately $25,000. All costs were incurred by government, either public health department or federal, because refugee health costs are paid by the federal government and the event response costs are covered by the public health department. CONCLUSION: A potentially preventable case of measles that was imported into the United States cost approximately $25,000 for the public health response. RECOMMENDATION: To maintain the elimination of measles transmission in the United States, U.S.-bound refugees should be vaccinated overseas. A refugee vaccination program administered during the overseas health assessment has the potential to reduce the risk of importation of measles and other vaccine-preventable disease and would eliminate costs associated with public health response to imported cases and outbreaks.


Assuntos
Custos de Cuidados de Saúde , Sarampo/diagnóstico , Sarampo/terapia , Refugiados , Humanos , Lactente , Kentucky , Sarampo/economia
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