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1.
Gastroenterol Hepatol ; 30(7): 375-80, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17692193

RESUMO

OBJECTIVE: To determine the diagnostic accuracy of computed tomography colonography (CTC) compared with conventional colonoscopy (CC). METHODS: Patients with an indication of CC were included. Fifty patients underwent CTC using multidetector CT before diagnostic colonoscopy was performed by an expert colonoscopist. Diagnostic accuracy was assessed individually both for each polyp and for each patient. RESULTS: Fifty patients were included and 40 polyps were analyzed. The by-polyp sensitivity of CTC was 15% for polyps 5 mm or less, 75% for polyps 5- 10 mm and 75% for polyps 10 mm or larger. By-patient specificity was 6% for polyps 5 mm or less, 75% for polyps 5-10 mm and 80% for polyps 10 mm or larger. The specificity of CTC was 94%. CTC was preferred over CC by 90% of the patients. The mean colonoscopy examination time was 30 minutes for CC and 35 minutes for CTC (p < 0.05). CONCLUSIONS: The sensitivity of CTC is moderate in detecting polyps larger than 10 mm, low in detecting 5-10 mm polyps and very low in detecting those less than 5 mm. The overall specificity of the procedure was 94%. Procedure time was lower with CC than with CTC but the latter was better tolerated by most patients.


Assuntos
Pólipos do Colo/diagnóstico , Colonografia Tomográfica Computadorizada , Colonoscopia , Pólipos/diagnóstico , Neoplasias Retais/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes
2.
Eur J Gastroenterol Hepatol ; 15(10): 1127-30, 2003 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-14501623

RESUMO

Achalasia is a disease of unknown origin in which there is a denervation of the myenteric plexus on the smooth muscle of the lower oesophageal sphincter, causing a cardial stenosis and a loss of efficacy of oesophageal peristalsis. The predominant symptoms are dysphagia for solids and liquids and regurgitation of the retained food. Occasionally, there may be oesophageal haemorrhage as a consequence of oesophagitis and stasis ulcers. An important but uncommon complication is the development of oesophageal cancer, which is typically squamous cell carcinoma. We report an exceptional case of a 77-year-old woman with a long-term achalasia and mega-oesophagus who presented four episodes of upper gastrointestinal bleeding in a 2 month period. The patient underwent surgical resection of the 10 cm of distal oesophagus, performing a partial fundoplication, and the pathological study revealed an oesophageal infiltration by a low-grade non-Hodgkin's lymphoma. After an insidious outcome, she died on the 47th day after admission.


Assuntos
Acalasia Esofágica/complicações , Neoplasias Esofágicas/etiologia , Leucemia Linfocítica Crônica de Células B/etiologia , Idoso , Neoplasias Esofágicas/patologia , Evolução Fatal , Feminino , Hemorragia Gastrointestinal/etiologia , Humanos , Leucemia Linfocítica Crônica de Células B/patologia , Recidiva
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