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1.
G Chir ; 41(1): 110-113, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32038021

RESUMO

Corpus luteum cyst rupture with consequent hemoperitoneum is a common cause of admission to the emergency room. This condition is frequently misdiagnosed because of overlapping of clinical findings in acute gynecologic diseases. However, an incorrect identification may lead to delay in surgical treatment, which can Romabe a life-threatening condition. Ultrasound (US) is the first technique used for diagnosis that can confirm or dismiss the presence of intraperitoneal fluid. Secondly, the contrast-enhanced computed tomography (CT) is the quickest way to identify the site of active bleeding and to establish the correct management of the clinical condition. Herein, we report a case of a 19-years-old girl with acute abdominal pain correctly identified by diagnostic images and treated with mini-invasive surgery techniques in order to quickly act without clinic and aesthetic sequelae.


Assuntos
Corpo Lúteo/cirurgia , Hemoperitônio/cirurgia , Laparoscopia/métodos , Cistos Ovarianos/cirurgia , Dor Abdominal/etiologia , Dor Aguda/etiologia , Meios de Contraste , Corpo Lúteo/diagnóstico por imagem , Feminino , Hemoperitônio/diagnóstico por imagem , Hemoperitônio/etiologia , Humanos , Cistos Ovarianos/complicações , Cistos Ovarianos/diagnóstico por imagem , Ruptura Espontânea/diagnóstico por imagem , Ruptura Espontânea/cirurgia , Ferida Cirúrgica , Tomografia Computadorizada por Raios X/métodos , Ultrassonografia , Adulto Jovem
2.
Eur Rev Med Pharmacol Sci ; 15(5): 509-14, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21744744

RESUMO

BACKGROUND: Polycystic ovary syndrome is the most common cause of chronic anovulation infertility in women in fertile period, and it's characterized by an increased production of androgens and estrogens. The administration of myo-inositol, a B complex vitamin, was associated with a decreased of serum testosterone and simultaneously, due to its ability to increase insulin sensitivity, women who received myo-inositol showed a great improvement of the ovulary function. Besides, the supplementation of inositol improves the oocytes' quality and increase the number of oocytes collected after ovarian stimulation in patients undergoing IVF (in vitro fertilization). AIM: The aim of this study is to determine the effects of myo-inositol on oocyte's quality on a sample of women with polycystic ovary syndrome. MATERIAL AND METHODS: The patients were divided into two groups: patients of Group A in-took 2 g of myo-inositol + 200 microg of folic acid (Inofolic, LO.LI. Pharma, Rome, Italy) while Group B only 200 microg of folic acid, both groups took the treatment twice a day, continuously for 3 months. RESULTS: At the end of treatment, the number of follicles of diameter > 15 mm, visible at ultrasound during stimulation, and the number of oocytes recovered at the time of pick-ups were found to be significantly greater in the group treated with myo-inositol, so as the aver-age number of embryos transferred and embryo Score S1. Significantly reduced was the average number of immature oocytes (vesicles germ and degenerated oocytes) too. CONCLUSIONS: These data suggest that myoinositol may be useful in the treatment of PCOS patients undergoing ovulation induction, both for its insulin-sensitizing activity, and its role in oocyte maturation.


Assuntos
Suplementos Nutricionais , Inositol/administração & dosagem , Oócitos/efeitos dos fármacos , Síndrome do Ovário Policístico/tratamento farmacológico , Adulto , Feminino , Humanos , Inositol/uso terapêutico , Indução da Ovulação
3.
Minerva Ginecol ; 62(6): 525-31, 2010 Dec.
Artigo em Italiano | MEDLINE | ID: mdl-21079574

RESUMO

AIM: Polycystic ovary syndrome is the most common cause of chronic anovulation infertility in women in fertile period. The supplementation of inositol, due to its ability to increase insulin sensitivity, improves the oocytes' quality and increase the number of oocytes collected after ovarian stimulation in patients undergoing IVF (In Vitro Fertilization). The aim of our study is to determine the effects of myo-inositol on oocyte's quality on a sample of women with polycystic ovary syndrome. METHODS: The patients were divided into two groups: patients of Group A intook 2 g of myo-inositol + 400 µg of folic acid 2 times a day, continuously for 3 months, while Group B only 400 µg of folic acid. RESULTS AND CONCLUSION: At the end of treatment, the number of follicles of diameter >15 mm, visible at ultrasound during stimulation, and the number of oocytes recovered at the time of pick-ups were found to be significantly greater in the group treated with myo-inositol, so as the average number of embryos transferred and embryo Grade G1. Significantly reduced was the average number of immature oocytes (vesicles germ and degenerated oocytes) too.


Assuntos
Fertilização in vitro/efeitos dos fármacos , Infertilidade Feminina/tratamento farmacológico , Inositol/administração & dosagem , Oócitos/efeitos dos fármacos , Síndrome do Ovário Policístico/tratamento farmacológico , Complexo Vitamínico B/administração & dosagem , Adulto , Quimioterapia Combinada , Feminino , Ácido Fólico/administração & dosagem , Humanos , Infertilidade Feminina/etiologia , Infertilidade Feminina/terapia , Folículo Ovariano/efeitos dos fármacos , Síndrome do Ovário Policístico/complicações , Síndrome do Ovário Policístico/diagnóstico , Estudos de Amostragem , Resultado do Tratamento
4.
Lab Chip ; 5(10): 1155-60, 2005 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16175273

RESUMO

MultiAnalyte immunoassays are often required to diagnose a pathologic condition. Here, we show how resistive-pulse sensing and multiple artificial pores can be integrated together on a single chip to detect different antigens rapidly and simultaneously. We use multiple pores on a single chip to detect the size change of latex colloids upon specific antigen-antibody binding on the colloid surface. As a proof-of-principle, we demonstrate our ability to detect simultaneously human G-CSF and GM-CSF antigens on a single chip. Our novel technique is a scalable technology that can lead to the sensing of at least N2 antigens simultaneously with an N N array of pores on a single chip.


Assuntos
Imunoensaio/instrumentação , Imunoensaio/métodos , Reações Antígeno-Anticorpo , Técnicas Biossensoriais , Eletroquímica , Eletrodos , Ensaio de Imunoadsorção Enzimática/métodos , Desenho de Equipamento , Fator Estimulador de Colônias de Granulócitos/imunologia , Fator Estimulador de Colônias de Granulócitos/metabolismo , Fator Estimulador de Colônias de Granulócitos e Macrófagos/imunologia , Fator Estimulador de Colônias de Granulócitos e Macrófagos/metabolismo , Humanos , Procedimentos Analíticos em Microchip/métodos , Microscopia Eletrônica de Varredura , Análise Serial de Proteínas/métodos , Estatística como Assunto
5.
Clin Exp Obstet Gynecol ; 27(1): 29-32, 2000.
Artigo em Inglês | MEDLINE | ID: mdl-10758795

RESUMO

The aim of this work was to test fetal stem cells (FSC) number modification in relation to clamping time and newborn effect. The results show that a fast sample, between 20 and 40 seconds, from umbilical cord after fetus birth and before placental detachment assured a greater quantity of blood useful for the transplants; and that it was necessary to enrich the collected blood in CD34+ cells with specific clonogenic culture, as this is otherwise a small number for a donation to an adult. In the "new donors" the effects of the unconscious donation always depend on the clamping time, which should be the shortest possible to avoid blood overload, which is very dangerous in the presence of heart malformation.


Assuntos
Coleta de Amostras Sanguíneas/métodos , Feto/fisiologia , Células-Tronco , Antígenos CD34/análise , Volume Sanguíneo , Constrição , Hematócrito , Humanos , Fatores de Tempo
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