[Early protected discharge of the mother and the neonate: case-control study]. / Dimissione precoce protetta della madre e del neonato: studio caso-controllo.

Aim of this study is to compare traditional post-partum hospital stay to hospitalization associated with early protected discharge: a case-control study has been performed to evaluate outcome as mother's appreciation of the experience as well as breastfeeding. The study included 50 healthy-term newborns and their mothers, discharged within 24 and 48 hours of life, and 44 controls, who had traditional "rooming-in" stay, delivered at the Department of Neonatology--University of Turin. The protocol included a midwife daily home visits and a neonatologist and nurse visit within 4th to 5th day of life, to evaluate mother's and baby's health status and to perform metabolic screenings. An ambulatorial follow-up visit at 1 month of life and 2 telephone interviews, at 3rd and 6th month, were also planned. During the first week of life 45 (90%) early discharged newborns had complete nursing (breastfeeding + water or other fluids), 4 (8%) had complementary nursing (breastfeeding + formula) and 1 (2%) received formula. Among controls, 46 (92%) babies received complete nursing, 2 had complementary nursing and 2 had artificial nursing. At 6 months of life breastfeeding was complete for 2% of cases and 6% of controls; in 44% of cases and 56% of controls nursing was complementary. Readmissions to our Birth Center were 2 among early discharged newborns, 1 in the control group. About project's appreciation, 96% of early discharged and 98% of control group mothers declared their availability to repeat the experience. Caring and supporting were judged adequate in 94% of both group. By adequate supporting of mother and newborn, short and traditional hospitalization are both pleasant and don't seem to present significant differences in type and length of nursing.

[Neonatal arteriovenous thrombosis: report of a case]. / Trombosi artero-venosa ad insorgenza prenatale: presentazione di un caso.

UNLABELLED: Limb vascular thrombosis is a severe, rare entity, often needing invasive surgery and sometimes leading to loss of function. An infant with in utero arteiro-venous thrombosis is reported. CASE REPORT: The baby, a female infant, was born at 34 weeks from a mother affected by gestational diabetes. She was referred to Neonatal Care Unit because of mild respiratory distress syndrome. She had no malformations. Spontaneous acute ischemia of right upper limb was noticed soon after admission: the limb appeared pale, cold, atonic and areflexic; no signs were noticed on it. Axillary artery and vein thromboses were soon confirmed by ultrasonography and arteriography. Intravenous administration of recombinant tissue plasminogen activator was carried on for 36 hours and followed by heparin and antithrombin III administration. Partial revascularization was obtained after a few hours: at the beginning of the treatment the limb became cyanotic, then edematous and finally the normal colour appeared everywhere but in the hand, was it became visible after a few days, when edema was reabsorbed. No recurrence of thrombosis occurred with heparin prophylaxis. Pain was treated with analgesic therapy, and motor impairment required physiotherapy. The doppler ultrasonographies which were performed subsequently confirmed a complete revascularization of axillary artery and vein. Coagulation and metabolic parameters (clotting tests, protein C, protein S, prothrombin, aminoacids) were studied but disorders predisposing to thrombosis were not found both in the patient and in her parents. CONCLUSION: Early identification of limb vascular thrombosis through external symptoms is very important, as it can avoid invasive surgical procedures.

[Triploidy syndrome: a case report]. / La sindrome da triploidia. Descrizione di un caso.

Triploidy is a complete extra set of chromosomes and results in a clinically recognizable lethal syndrome with hydatiform placental changes, severe intrauterine growth deficiency, cranial bone abnormalities, eye defects, malformed ears, syndactyly, genital anomalies, congenital heart defects and brain anomalies. Less severe are instances of diploid-tetraploid mixoploidy and patients are more likely to survive. The present report is another contribution to the knowledge of human triploidy: we describe a 69,XXY triploid male occurred to our observation.

[The efficacy of aztreonam in a "bolus dose" in the therapy of urinary tract infections in neonates]. / Efficacia dell'aztreonam in "bolus dose" nella terapia delle infezioni delle vie urinarie nel neonato.

A "bolus dose" of aztreonam was used to treat a sample group of 46 neonates suffering from urinary tract infections caused by bacteria thought to be sensitive to aztreonam. This treatment proved efficacious in approximately 80% of cases.

[Diagnostic and prognostic value of blood prealbumin in the course of neonatal infectious diseases of bacterial origin]. / Valore diagnostico e prognostico della prealbumina serica nel corso di malattie infettive neonatali di origine batterica.

Serum prealbumin levels were determined in a sample of newborns suffering from infectious diseases of bacterial origin. The diagnostic and prognostic significance was assessed.

[Surveillance of congenital malformations. Experiences in 1986-1987]. / Sorveglianza delle malformazioni congenite. Esperienza relativa al biennio 1986-1987.

Epidemiological data on the congenital malformations detected in 8,723 newborns over a two year period are presented.

[Influence of salivary Ph on the correlation between salivary and plasma levels of phenobarbital in the neonatal period]. / Influenza del pH salivare sulla correlazione tra tassi salivari e plasmatici del fenobarbital in epoca neonatale.

The influence of salivary pH on the estimate of blood barbiturates obtained by measuring phenobarbital on saliva at newborn age.

[Monitoring of phenobarbital use during the neonatal period by means of urinalysis]. / Monitoraggio del fenobarbital in epoca neonatale mediante dosaggio su urine.

Monitoring of blood barbiturate level was performed in 32 term newborns, who received 6 mg/Kg/die phenobarbital (PB), by assaying blood and urine samples. Cases were grouped according to duration of treatment which varied following multiples of 12 hours from 16 to 100 hours. Serum and urine PB assay was conducted through immunological percentage nephelometric inhibition. Plasma and urine PB levels within each group were significantly correlated (r = 0.8826; p less than 0.001), indicating that, if PB treatment is given without variations in dosage and if diuresis is not impaired, blood barbiturate level may be monitored through urine assays.

[The newborn infant of the drug-addicted mother. Experience relative to the period 1978-1986]. / Il neonato da madre tossicodipendente. Esperienze relative al periodo 1978-1986.

Ninety-seven newborns of drug addicted mothers observed in the period 1978-1986 were compared with the same number of controls. Pregnancies are at risk and newborns suffer a higher incidence of tainted amniotic liquid, low birth weight and preterm gestation. The withdrawal syndrome is the most commonly encountered pathology of such newborns.

[Epidemiologic investigation of microorganisms and their sensitivity to antibiotics in a neonatal pathology center 1981-1984]. / Indagine epidemiologica sui microrganismi e sulla loro sensibilità agli antibiotici in un centro di patologia neonatale nel triennio 1981-1984.

The cultures performed over a period of three years in a neonatal pathology unit were studied to determine the epidemiological behaviour of the microorganisms present and variations in time of their sensitivity to antibiotics.