[Contemporary approaches in evaluation of pro- and antioxidant status in combined forms of occupational diseases due to functional overstrain].

Complex evaluation covered parameters pro- and antioxidant system in some somatic diseases, mostly in arthrosis and polyneuropathies due to occupational factor of functional overstrain. The results obtained prove influence of prolonged occupational functional overstrain causing excessive free oxidative radicals formation, strain of antioxidant status and subsequent oxidant stress--that is clinically manifested with "mutual burden" syndrome in combined occupational diseases.

[Some aspects of cognitive functions in chronic intoxication by organic solvents].

Study covered 20 females with chronic intoxication with organic solvents, who worked long as painters on industrial enterprise. To reveal clinically significant cognitive disorders, Mini-Cog scale was applied. Drawing test helped to reveal visual and spatial disorders, restults were expressed in scores. Memory was evaluated through methods "operative memory", "short-term memory", "memory for figures", "memory for images", "hearing memory"--that proved lower results in the main group of examinees. In 75% of patients with occupational diseases caused by organic solvents, moderate cognitive disorders of amnestic multifunctional type were seen. 100% of individuals having chronic intoxication with organic solvents demonstrated encephalopathy. In comparison with reference group, the main group members had more frequent 1 and 2 degrees encephalopahy.