RESUMO
In Daghestan in the focus of the flood-plain swamp type 64 persons fell ill with tularemia in 1999. During the epizootological survey 8 Francisella tularensis strains were isolated from vectors and carriers and in 7 samples taken from open water reservoirs, as well as in 1 sample obtained from Ixodes ticks, tularemia antigen was detected. Humans were infected mainly by the transmissive route, as found in 71.8% of patients. 28% of patients were infected through contacts. The disease took mainly a mild course, registered in 95.6% of patients. The disease affected those persons who had not been immunized against tularemia.
Assuntos
Surtos de Doenças , Reservatórios de Doenças , Francisella tularensis , Tularemia/epidemiologia , Adolescente , Adulto , Animais , Vacinas Bacterianas/administração & dosagem , Criança , Pré-Escolar , Daguestão/epidemiologia , Transmissão de Doença Infecciosa , Vetores de Doenças , Francisella tularensis/imunologia , Francisella tularensis/isolamento & purificação , Água Doce/microbiologia , Humanos , Lactente , Pessoa de Meia-Idade , Roedores/microbiologia , População Rural , Tularemia/prevenção & controle , Tularemia/transmissão , Vacinação , GuerraRESUMO
The clinico-pathophysiological analysis of the main forms of extrapyramidal dyskinesias is discussed. The authors distinguish 2 main forms of hyperkinesias and dystonias which are designated conditionally phasic and tonic. Stereotaxic interventions on deeply located brain structures (ventrolateral complex of thalamic nuclei, subthalamic region, putamen, dentate nuclei of cerebellum) are substantiated anatomicofunctionally. On the basis of the results of 569 stereotaxic operations the indications and contraindications for various types of operative interventions were elaborated. The result was good in 26.7% of patients, considerable improvement occurred in 32%, mild improvement in 32.6%, no changes occurred in the condition of 5.2% of patients.