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1.
Science ; 384(6691): 48-53, 2024 Apr 05.
Artigo em Inglês | MEDLINE | ID: mdl-38574139

RESUMO

Understanding universal aspects of quantum dynamics is an unresolved problem in statistical mechanics. In particular, the spin dynamics of the one-dimensional Heisenberg model were conjectured as to belong to the Kardar-Parisi-Zhang (KPZ) universality class based on the scaling of the infinite-temperature spin-spin correlation function. In a chain of 46 superconducting qubits, we studied the probability distribution of the magnetization transferred across the chain's center, [Formula: see text]. The first two moments of [Formula: see text] show superdiffusive behavior, a hallmark of KPZ universality. However, the third and fourth moments ruled out the KPZ conjecture and allow for evaluating other theories. Our results highlight the importance of studying higher moments in determining dynamic universality classes and provide insights into universal behavior in quantum systems.

2.
Science ; 383(6689): 1332-1337, 2024 Mar 22.
Artigo em Inglês | MEDLINE | ID: mdl-38513021

RESUMO

Engineered dissipative reservoirs have the potential to steer many-body quantum systems toward correlated steady states useful for quantum simulation of high-temperature superconductivity or quantum magnetism. Using up to 49 superconducting qubits, we prepared low-energy states of the transverse-field Ising model through coupling to dissipative auxiliary qubits. In one dimension, we observed long-range quantum correlations and a ground-state fidelity of 0.86 for 18 qubits at the critical point. In two dimensions, we found mutual information that extends beyond nearest neighbors. Lastly, by coupling the system to auxiliaries emulating reservoirs with different chemical potentials, we explored transport in the quantum Heisenberg model. Our results establish engineered dissipation as a scalable alternative to unitary evolution for preparing entangled many-body states on noisy quantum processors.

3.
Phys Rev E Stat Nonlin Soft Matter Phys ; 70(1 Pt 1): 011908, 2004 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-15324089

RESUMO

Postinhibitory rebound is a nonlinear phenomenon present in a variety of nerve cells. Following a period of hyperpolarization this effect allows a neuron to fire a spike or packet of spikes before returning to rest. It is an important mechanism underlying central pattern generation for heartbeat, swimming and other motor patterns in many neuronal systems. In this paper we consider how networks of neurons, which do not intrinsically oscillate, may make use of inhibitory synaptic connections to generate large scale coherent rhythms in the form of cluster states. We distinguish between two cases (i) where the rebound mechanism is due to anode break excitation and (ii) where rebound is due to a slow T-type calcium current. In the former case we use a geometric analysis of a McKean-type model to obtain expressions for the number of clusters in terms of the speed and strength of synaptic coupling. Results are found to be in good qualitative agreement with numerical simulations of the more detailed Hodgkin-Huxley model. In the second case we consider a particular firing rate model of a neuron with a slow calcium current that admits to an exact analysis. Once again existence regions for cluster states are explicitly calculated. Both mechanisms are shown to prefer globally synchronous states for slow synapses as long as the strength of coupling is sufficiently large. With a decrease in the duration of synaptic inhibition both systems are found to break into clusters. A major difference between the two mechanisms for cluster generation is that anode break excitation can support clusters with several groups, while slow T-type calcium currents predominantly give rise to clusters of just two (antisynchronous) populations.


Assuntos
Potenciais de Ação/fisiologia , Relógios Biológicos/fisiologia , Modelos Neurológicos , Rede Nervosa/fisiologia , Inibição Neural/fisiologia , Neurônios/fisiologia , Transmissão Sináptica/fisiologia , Adaptação Fisiológica/fisiologia , Animais , Encéfalo/fisiologia , Análise por Conglomerados , Simulação por Computador , Limiar Diferencial/fisiologia , Humanos , Potenciais da Membrana/fisiologia , Processos Estocásticos
4.
Phys Rev E Stat Nonlin Soft Matter Phys ; 64(2 Pt 1): 021913, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11497626

RESUMO

We study numerically nonlinear responses of a periodically forced Hodgkin-Huxley neuron. The coherence of the system in the absence of external noise, namely, the "intrinsic stochastic resonance," is evidenced by the multimodal aperiodic firing pattern, a bell-shaped curve in the signal-to-noise ratio, and the statistical features of the mean firing rate. The subthreshold intrinsic oscillations enhance the signal transduction in a manner different from that in models studied previously.


Assuntos
Potenciais de Ação/fisiologia , Relógios Biológicos/fisiologia , Potenciais da Membrana/fisiologia , Modelos Neurológicos , Neurônios/fisiologia , Processos Estocásticos , Transmissão Sináptica/fisiologia , Simulação por Computador , Estimulação Elétrica
5.
Artigo em Inglês | MEDLINE | ID: mdl-11046318

RESUMO

The coherence resonance (CR) of globally coupled Hodgkin-Huxley neurons is studied. When the neurons are set in the subthreshold regime near the firing threshold, the additive noise induces limit cycles. The coherence of the system is optimized by the noise. The coupling of the network can enhance CR in two different ways. In particular, when the coupling is strong enough, the synchronization of the system is induced and optimized by the noise. This synchronization leads to a high and wide plateau in the local CR curve. A bell-shaped curve is found for the peak height of power spectra of the spike train, being significantly different from a monotonic behavior for the single neuron. The local-noise-induced limit cycle can evolve to a refined spatiotemporal order through the dynamical optimization among the autonomous oscillation of an individual neuron, the coupling of the network, and the local noise.


Assuntos
Modelos Neurológicos , Rede Nervosa/fisiologia , Neurônios/fisiologia , Animais , Fenômenos Biofísicos , Biofísica , Eletrofisiologia , Potenciais Pós-Sinápticos Excitadores , Dinâmica não Linear , Processos Estocásticos
8.
Vopr Onkol ; 22(3): 29-32, 1976.
Artigo em Russo | MEDLINE | ID: mdl-936524

RESUMO

As a result of investigation and treatment of 5000 patients with disorders in menstrual function and endocrinous sterility sclerocystic ovaries were diagnosed in 1.8-2% (90 patients). In 6 of them ovarian changes were associated with cancer of the uterine body. In uterine body cancer and sclerocystic ovaries opsomenorrhea and menorrhagia, obesity were of great persistance, the duration of the disease being 12-20 years. Based on the conducted investigations it is considered rational to perform a wedge resection as early as possible, but not following many years of unsuccessful hormone therapy, and to study histologically endometrial curettage specimens. In recurrence of the disease and enlargement even of one ovary a repeat wedge ovariectomy should be performed.


Assuntos
Adenocarcinoma/complicações , Síndrome do Ovário Policístico/complicações , Neoplasias Uterinas/complicações , 17-Cetosteroides/urina , Adolescente , Adulto , Feminino , Humanos , Distúrbios Menstruais/complicações , Síndrome do Ovário Policístico/cirurgia , Síndrome do Ovário Policístico/urina , Neoplasias Uterinas/cirurgia , Neoplasias Uterinas/urina
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