[Macular morphology and peripapillary retinal nerve fiber layer thickness in children with regressed retinopathy of prematurity]. / Morfologia siatkówki w plamce i grubosc warstwy wlókien nerwowych tarczy nerwu wzrokowego u dzieci z przebyta retinopatia wczesniaków.

PURPOSE: morphobiometric evaluation of macula and peripapillary retinal nerve fiber layer thickness with the use of high-resolution optical coherence tomography in children with a history of regressed retinopathy or prematurity. MATERIALS AND METHODS: 18 patients at the age of 8 to 14 years with a history of spontaneously regressed retinopathy of prematurity were studied prospectively. For statistical purposes a control group of 21 matched subjects at the age of 8 to 15 years was used. Ophthalmic examination and optical coherence tomography were performed in each patient. Peripapillary nerve fibre layer thickness, foveal and parafoveal thickness ratio, total macular volume and subfoveal choroidal thickness were measured in both groups. RESULTS: in the optical coherence tomography, the foveal thickness in children with retinopathy of prematurity was significantly higher [269.5 µm (232-321)] compared to the controls [224.5 µm (207-267)]. The macular volume in the study group was also higher (8.68 mm³). The subfoveal choroidal thickness was reduced in study group [321 µm (112-365)] compared to the control group [337 µm (294-358)]. There was no statistical significant difference in total peripapillary nerve fibre layer thickness between the two groups. CONCLUSION: The morphobiometric macular changes in eyes with a history of regressed retinopathy of prematurity are possibly related to the developmental abnormalities, which retinopathy of prematurity is due to the presence of the abnormal foveal structure across all retinal layers.

[Optic nerve head drusen in children--visual function and OCT outcomes]. / Druzy tarczy nerwu wzrokowego u dzieci- -funkcja widzenia a obraz OCT.

PURPOSE: To evaluate the effect of optic nerve head drusen on retinal nerve fiber layer (RNFL) thickness in children, with the use of optical coherence tomography (OCT). MATERIAL AND METHODS: 21 patients (mean age 13.9 years) with optic nerve head drusen were studied prospectively. For statistic comparison a group of 15 control subjects (mean age 14.1 years) participated. Ophthalmologic examination, automated visual field testing and optical coherence tomography were performed in each patient. For statistical analysis we used Shapiro-Wilk and U Mann-Whitney tests. RESULTS: In the OCT measurements the nasal RNFL was significantly thinner as compared to the reference group. Neither statistically significant thinning of global RNFL between groups nor relation between subjects age and RNFL thickness was found. CONCLUSIONS: Optic nerve head drusen can lead to visual function defects, therefore early and correct diagnosis is mandatory. Optical coherence tomography is a usefull diagnostic tool used to determine the cause of disc elevation, which is especially important in childhood, when drusen can cause disc to appear papilledema-like. Overall OCT appears to be a non-invasive, sensitive and early-indicating method of RNFL thinning.