1.
Arch Pharm Res
; 28(2): 142-50, 2005 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15789741
RESUMO
The synthesis and structure-activity relationships of a novel series of substituted quercetins that activates peroxisome proliferator-activated receptor gamma (PPARgamma) are reported. The PPARgamma agonistic activity of the most potent compound in this series is comparable to that of the thiazolidinedione-based antidiabetic drugs currently in clinical use.