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Artigo em Inglês | MEDLINE | ID: mdl-35652906

RESUMO

Two hundred and two hazelnut paste samples from various hazelnut processing plants in the Black Sea Region of Turkey were analysed for the incidence of aflatoxins (AFs) by liquid chromatography coupled with fluorescence detection (LC-FLD). All 202 (100%) hazelnut paste samples were contaminated with various AFs ranged from 0.17 to 12.96 µg kg-1. AF contamination level of four (1.98%) samples exceeded legal limits. Risk assessment for hazelnut paste was determined by using AF incidence results, and the margin of exposure (MOE) and hepatocellular carcinoma (HCC) risk approach were applied. For the adult Turkish population (15+ years age group), the average lower bound (LB) and upper bound (UB) exposure levels for aflatoxin B1 (AFB1) and total aflatoxins (AFT) were 0.0106-0.0107 ng kg-1 body weight (bw) per day and 0.0250 ng kg-1 bw per day, respectively. MOE estimates for mean and 95th percentile exposures to AFB1 for hazelnut paste were higher than 10,000, which indicates no potential health concern for Turkish adults. HCC for the Turkish population was 0.00023 cases per 100,000 people per year. The study indicates that Turkish population is not under this toxicological risk when consuming hazelnut paste containing food products.


Assuntos
Aflatoxinas , Carcinoma Hepatocelular , Corylus , Neoplasias Hepáticas , Adulto , Aflatoxina B1/análise , Aflatoxinas/análise , Cromatografia Líquida de Alta Pressão/métodos , Corylus/química , Contaminação de Alimentos/análise , Humanos , Medição de Risco , Turquia
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