1.
Pediatr Neurol
; 39(6): 423-5, 2008 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19027589
RESUMO
We report on a case of Cobb syndrome, a rare metameric disorder, characterized by a vascular abnormality of the spinal cord, with an associated vascular skin lesion of the same metamere, in an 8-year-old girl presenting with leg weakness. Magnetic resonance imaging revealed a spinal arteriovenous malformation at the level of T(10)-L(5). This finding, together with a large, pigmented nevus at this level, is diagnostic for Cobb syndrome. A systematic review of the literature on Cobb syndrome, with a focus on treatment and outcomes, is presented. Current treatment options include combinations of embolization, neurosurgical intervention, corticosteroid therapy, and radiotherapy.
Assuntos
Malformações Vasculares do Sistema Nervoso Central/complicações , Dermatopatias/complicações , Doenças da Coluna Vertebral/complicações , Criança , Feminino , Humanos , Imageamento por Ressonância Magnética
2.
J Paediatr Child Health
; 44(11): 676-7, 2008 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19012645