Non-secretory solitary plasmacytoma of the spleen.

A case of primary nonsecretory plasmacytoma of the spleen is reported. On laparotomy and splenectomy a 920 g spleen was removed, measuring 16 x 14 x 6 cm. The cut surface of the entire spleen showed that the tumour occupied most of the splenic tissue. A bone marrow aspirate and trephine, skeletal survey showed no signs of myeloma. Biopsy of the liver and regional lymph nodes was normal. Immunocytochemistry of the splenic tumour showed positivity for pan-B and plasma cell markers. After splenectomy the patient was treated with chemotherapy according to protocol VBCMP (M2).

Multiple leiomyosarcoma of the stomach.

Leiomyosarcoma is the second most common non epithelial malignant tumor of the stomach. It is almost always a single lesion. Multiple leiomyosarcomas of the stomach are extremely rare. To our knowledge only three cases have been reported so far. We present a 40 year old female with epigastric pain, nausea, diarrhea, weight loss and melena in whom we diagnosed multiple lesions of the stomach. At operation, we found a total of 11 submucosal or subserosal lesions ranging in size from 0.5 to 6 cm in diameter localized throughout the stomach. Histological examination showed leiomyosarcoma in every lesion. Almost all the lymph nodes along curvatures had metastases. Other lymph nodes, peritoneum, liver and other organs were disease free. A total gastrectomy and Roux-en-Y esophagojejunostomy was performed. She had an uneventful recovery and has remained symptom-free so far (nine months).

Inherited combined deficiency of factors XI and XII with von Willebrand's disease.

Combined hereditary deficiency of factors XI (FXI) and XII (FXII) associated with the deficeincy of von Willebrand factor (vWF) in a single patient has not been reported so far in the literature. We report on two brothers of non-Jewish stock with defciency of FXI, FXII and vWF. The family studies disclosed FXI and FXII deficiency in the mother of propositi. A maternal niece had FXII deficiency. The father of propositi had vWF deficiency. This study suggests possible existence of a regulatory factor common to genes specifying FXI and FXII. Associated vWF deficiency is coincidental.

[Isolated tuberculosis of the liver--case report]. / Izolovana tuberkuloza jetre--prikaz bolesnice.

Tuberculosis of the liver is rare even in areas where tuberculosis is widespread. Isolated tuberculosis of the liver is extremely rare. It usually presents as a nodular - pseudo-tumorous form. Tuberculosis of the bile ducts is even less frequent. A 37 year old woman with nodular - pseudotumorous form of tuberculosis of the liver is presented. The diagnosis was established after surgical biopsy and histology. It may be caused by the bovine type of the bacillus. The patient had an excellent response to tuberculostatic drugs. Tuberculosis of the liver must be taken into account in the differential diagnosis of the liver masses.

[Mesenteric panniculitis--case report]. / Mezentericni panikulitis--prikaz bolesnika.

Mesenteric panniculitis is a very rare disease usually involving the mesentery of the small bowel, less frequently the sigmoid colon or other intraabdominal fat tissue. The disease is benign with a favorable prognosis. Diagnosis is, as a rule, established at operation or autopsy and histology. A 58 year old male with this disease is presented. The paticut hod mild abdominal pain and a palpable mass. A tumor of the mesentery was suspected on CT scan. The exact diagnosis was established at operation and confirmed at histology.