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Biomolecules ; 13(5)2023 04 25.
Artigo em Inglês | MEDLINE | ID: mdl-37238615

RESUMO

Recent advances in developing and screening candidate pharmacotherapies for psychiatric disorders have depended on rodent models. Eating disorders are a set of psychiatric disorders that have traditionally relied on behavioral therapies for effective long-term treatment. However, the clinical use of Lisdexamfatamine for binge eating disorder (BED) has furthered the notion of using pharmacotherapies for treating binge eating pathologies. While there are several binge eating rodent models, there is not a consensus on how to define pharmacological effectiveness within these models. Our purpose is to provide an overview of the potential pharmacotherapies or compounds tested in established rodent models of binge eating behavior. These findings will help provide guidance for determining pharmacological effectiveness for potential novel or repurposed pharmacotherapies.


Assuntos
Transtorno da Compulsão Alimentar , Bulimia Nervosa , Bulimia , Terapia Cognitivo-Comportamental , Humanos , Transtorno da Compulsão Alimentar/tratamento farmacológico , Transtorno da Compulsão Alimentar/diagnóstico , Transtorno da Compulsão Alimentar/psicologia , Bulimia/diagnóstico , Bulimia/psicologia , Bulimia/terapia , Bulimia Nervosa/diagnóstico , Bulimia Nervosa/psicologia , Bulimia Nervosa/terapia
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