Doxorubicin causes cachexia, sarcopenia, and frailty characteristics in mice.

While chemotherapy treatment can be lifesaving, it also has adverse effects that negatively impact the quality of life. To investigate the effects of doxorubicin chemotherapy on body weight loss, strength and muscle mass loss, and physical function impairments, all key markers of cachexia, sarcopenia, and frailty. Seventeen C57/BL/6 mice were allocated into groups. 1) Control (n = 7): mice were exposed to intraperitoneal (i.p.) injections of saline solution. 2) Dox (n = 10): mice were exposed to doxorubicin chemotherapy cycles (total dose of 18 mg/kg divided over 15 days). The body weight loss and decreased food intake were monitored to assess cachexia. To assess sarcopenia, we measured muscle strength loss using a traction method and evaluated muscle atrophy through histology of the gastrocnemius muscle. To evaluate physical function impairments and assess frailty, we employed the open field test to measure exploratory capacity. Doxorubicin administration led to the development of cachexia, as evidenced by a significant body weight loss (13%) and a substantial decrease in food intake (34%) over a 15-day period. Furthermore, 90% of the mice treated with doxorubicin exhibited sarcopenia, characterized by a 20% reduction in traction strength (p<0,05), a 10% decrease in muscle mass, and a 33% reduction in locomotor activity. Importantly, all mice subjected to doxorubicin treatment were considered frail based on the evaluation of their overall condition and functional impairments. The proposed model holds significant characteristics of human chemotherapy treatment and can be useful to understand the intricate relationship between chemotherapy, cachexia, sarcopenia, and frailty.

Association between childhood anthropometric indicators and bone mineral density in adulthood / Associação entre indicadores antropométricos na infância e densidade mineral óssea na idade adulta

ABSTRACT Objective: This study aimed to verify the association between childhood anthropometric indicators and areal bone mineral density (aBMD) in adulthood. Methods: Repeated measures of 137 subjects (68 females) were obtained in childhood (9.2±1.5 years of age) and adulthood (22.3±1.7 years of age). aBMD (g/cm2) was assessed for whole body, lumbar spine, upper and lower limbs, and femoral neck in adulthood using dual-energy X-ray absorptiometry. Anthropometric measurements of body weight (BW), height, triceps and subscapular skinfolds were obtained in childhood. The anthropometric indicators used were BW, body mass index (BMI), and sum of skinfolds (ΣSF). Simple linear regression was used to assess the association between childhood anthropometric indicators and aBMD in adulthood, controlled by chronological age and stratified by sex, with 5% statistical significance. Results: In females, multiple associations were observed between anthropometric indicators and aBMD, with higher coefficients for BMI (β=0.020; R2=0.20; p<0.01 for right femoral neck to β=0.008; R2=0.16; p<0.01 for upper limbs), followed by BW (β=0.003; R2=0.21; p<0.01 for upper limbs to β=0.008; R2=0.20; p<0.01 for right femoral neck) and ΣSF (β=0.001; R2=0.06; p<0.01 for upper limbs to β=0.005; R2=0.12; p<0.01 for right femoral neck). In males, associations were observed only for the lumbar spine region (β=0.016; R2=0.09 for BMI to β=0.004; R2=0.06; p<0.01 for ΣSF). Conclusions: Anthropometric indicators of childhood proved to be sensitive predictors of aBMD in adulthood, especially in females. BMI indicated a greater association with aBMD in both sexes.

RESUMO Objetivo: O objetivo do estudo foi verificar a associação entre os indicadores antropométricos da infância com a área da densidade mineral óssea (aDMO) na idade adulta. Métodos: Medidas repetidas de 137 sujeitos (68 do sexo feminino) foram obtidos na infância (9,2±1,5 anos de idade) e idade adulta (22,3±1,7 anos de idade). A aDMO (g/cm2) foi avaliada para todo o corpo, coluna lombar, membros superiores e inferiores e colo do fêmur na idade adulta usando a absorciometria radiológica de dupla energia (DXA). Medidas antropométricas de peso corporal, estatura e dobras cutâneas das regiões tricipital e subescapular foram obtidas na infância. Os indicadores antropométricos utilizados para as análises foram o peso corporal (PC), o índice de massa corporal (IMC) e o somatório de dobras cutâneas (ΣDC). Regressão linear simples controlada pela idade e estratificada por sexo foi empregada para avaliar a associação entre os indicadores antropométricos do período da infância na aDMO na idade adulta, com significância estatística de 5%. Resultados: No sexo feminino, múltiplas associações foram observadas entre os indicadores antropométricos e a aDMO, com maiores coeficientes para IMC (β=0,020; R2=0,20; p<0.01 para colo do fêmur direito a β=0,008; R2=0,16; p<0,01 para membros superiores), seguido da PC (β=0,003; r2=0,21; p<0,01 para membros superiores a β=0,008; r2=0,20; p<0,01 para colo do fêmur direito) e ΣDC (β=0,001; R2=0,06; p<0,01 para membros superiores a β=0,005; R2=0,12; p<0,01 para colo do fêmur direito). No sexo masculino, associações ocorreram apenas na região da coluna (β=0,016; R2=0,09 para IMC a β=0,004; R2=0,06; p<0,01 para ΣDC). Conclusões: Indicadores antropométricos da infância mostraram ser sensíveis preditores da aDMO na idade adulta, especialmente no sexo feminino. O IMC indicou maior associação com a aDMO em ambos os sexos.

Time Reallocations From Sedentary Behavior to Physical Activity and Cardiovascular Risk Factors in Children and Adolescents: A Systematic Review.

BACKGROUND: Recent statistical approaches have allowed consideration of the integrated relationships between sedentary behavior (SB) and physical activity (PA) with different health outcomes. The present paper aimed to systematically review the literature and synthesize evidence about associations between hypothetical reallocations from SB to different PA intensities and cardiovascular risk factors in youth. METHODS: A systematic search of 8 databases was performed. Observational studies with a population of children and/or adolescents and based on statistical analysis that investigated the associations between time reallocations from SB to PA and cardiovascular risk factors were included. RESULTS: Twenty-eight studies met the inclusion criteria. Level of evidence (derived from cross-sectional studies) indicated that the reallocation from SB to moderate to vigorous PA was beneficially associated with adiposity, cardiorespiratory fitness, and cardiometabolic biomarkers in youth. Reallocation from SB to light PA was not associated with the analyzed outcomes. Associations derived from longitudinal studies were mostly inconclusive. CONCLUSION: Cardiovascular risk factors could be improved by increasing moderate to vigorous PA at the expense of time spent in SB in pediatric populations. Prospective studies or studies investigating the effects of reallocating sedentary bouts to PA are needed.

Maturity-associated variation in the body size, physical fitness, technical efficiency, and network-based centrality measures in young soccer players.

This study aimed to observe the relationships between the maturity status on the network-based centrality measures of young athletes in small-sided soccer games (SSG). The study included 81 male players (14.4 ± 1.1 years). Measurements included height, sitting height, body mass, and bone age (TW3 method). The applied protocols were the following: Countermovement Jump (CMJ), Yo-Yo Intermittent Recovery Test Level 1 (YYIRT1), Repeated Sprints Ability (RSA), observational analysis of techniques, and interactions performed by players in SSG. The relationship between the set of evaluated variables within each maturity status was obtained from the correlational analysis of networks (P < 0.05). The maturity status explained a significant portion of the variance in body mass (η2 = 0.37), height (η2 = 0.30), sitting height (η2 = 0.30), and performance on the YYIRT1 (η2 = 0.08), CMJ (η2 = 0.14), and RSA (η2 = 0.13). No effect of maturity status on network-based centrality measures of young athletes was identified (P > 0.05). For the late maturity group, there was a correlation between the degree of centrality and physical growth indicators (rmean = 0.88). For players with maturation "on time", physical growth indicators relate to the degree of prestige (rmean = 0.36). It is concluded that body size and bone age impact how late and on-time maturity groups interact within the match.

Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood.

BACKGROUND: This study was aimed to examine the relationship between muscular fitness indicators in childhood and areal bone mineral density (aBMD) in adulthood and to verify whether the relationship is mediated by performance on muscular fitness indicators in adulthood. METHODS: A sample of 138 healthy adults (69 males; 22.3 years) were followed after a previous assessment at the age of 7-10 years. Stature, body mass and muscular fitness indicators (handgrip strength, standing long jump and sit-ups tests) were assessed in childhood and adulthood. Additionally, total body, upper limbs, lower limbs, right femoral neck and lumbar spine aBMD was assessed in adulthood using dual X-ray absorptiometry. Analysis included descriptive statistics; t-test or Mann-Whitney U-test for comparison between males and females, multiple linear regression for the prediction aBMD from muscular fitness indicators in childhood, mediation analysis of the respective muscular fitness indicators in adulthood and the relationship between muscular fitness indicators in childhood and aBMD. RESULTS: Males were stronger compared to females regarding muscular fitness indicators in childhood and adulthood, and presented higher mean values for aBMD in adulthood, except for lumbar spine (p < 0.05). Regression analysis revealed that some muscular fitness indicators in childhood showed significant positive relationship with bone health indicators in adulthood, such as: handgrip strength and total body aBMD (ß = 0.005; R2 = 0.35; p = 0.040) and upper limbs aBMD (ß = 0.005; R2 = 0.55; p = 0.019); and sit-ups test was a significant predictors of lumbar spine BMD (ß = 0.003; R2 = 0.06; p = 0.039). Mediation analysis pointed out the following: adulthood handgrip strength mediated relationships between childhood handgrip strength and total aBMD (indirect effect (IE) = 0.0025; 95%CI = 0.0005-0.0048), and upper limbs aBMD (IE = 0.0040; 95%CI = 0.0017-0.0069). CONCLUSIONS: Muscular fitness indicators in childhood showed significant relationship with bone health indicators in adulthood and the sit-ups test in childhood had direct effect on lumbar spine aBMD in adulthood. Adulthood handgrip strength mediated the relationship between childhood handgrip strength and total body and upper limb aBMD, pointing out that muscular fitness in childhood may be a aBMD determinant in adulthood, especially when higher muscle fitness performance is maintained in adulthood.

Using Social Network Analysis to Study Relationships Between Young Soccer Players' Bone Age, Body Size, and the Centrality of Their Pass Interactions.

Prior research has suggested relevance to anthropometric variance of youth athletes at various stages of their maturation, and prior studies of youth players' soccer skills have failed to consider their interdependent interactions during play. Accordingly, to address both of these separate research omissions, we aimed in this study to analyze the relationships between young (U-13 and U-15 groups) soccer players' bone age and body size indicators and centrality measures of their pass interactions during small sided games. We included young 81 athletes (M age = 14.4, SD = 1.1 years) from whom we took anthropometric measurements of body mass, height, and trunk-cephalic height and obtained their bone age using the Tanner-Whitehouse 3 classification method. We also filmed small-sided games in the goal keeper/three player (GK3-3GK) format to analyze the centrality of their passing actions on the following measures: degree of centrality, closeness of centrality, degree of prestige, and proximity of prestige. There were no group differences in the prominence of passing actions across these three measures (tmean = -3.13; p > .05). Canonical correlations of these relationships were significant only in the U-13 group, in which centrality in passing actions was related to body size (r = 0.71; R2 = 0.21; ʌ = 0.28; p = .03). U-13 players who were physically larger and who presented higher bone age showed centralized main passing actions.

Relationship Between Body Size and Skeletal Age with Muscle Damage in Young Soccer Players.

This study verified the relationship between body size and skeletal age (SA) with the behavior of blood markers of muscle damage and delayed onset muscle soreness (DOMS) after a soccer match in the U-13 and U-15 categories. The sample consisted of 28 soccer players in the U-13 and 16 in the U-15 categories. Creatine kinase (CK), lactate dehydrogenase (LDH), and DOMS were evaluated up to 72 h after the match. Muscle damage was elevated at 0 h in U-13, and from 0 h to 24 h in U-15. DOMS increased from 0 h to 72 h in U-13 and from 0 h to 48 h in U-15. Significant associations of SA and fat-free mass (FFM) with muscle damage markers and DOMS were observed only in U-13, specifically at time 0 h, when SA explained 56% of CK and 48% of DOMS and FFM explained 48% of DOMS. We concluded that in the U-13 category, higher SA is significantly associated with muscle damage markers, and increase in FFM is associated with muscle damage markers and DOMS. Furthermore, U-13 players need 24 h to recover pre-match muscle damage markers and more than 72 h to recover DOMS. In contrast, the U-15 category needs 48 h to recover muscle damage markers and 72 h to recover DOMS.

Body size, maturation and motor performance in young soccer players: relationship of technical actions in small-sided games.

The objective of this study was to investigate the relative contributions of body size, skeletal age, and motor performance variables with technical actions through an ecological model during small-sided soccer games, and the interaction of biological maturation with technical and motor performance in young players. In this cross-sectional study, eighty-two young players (14.4 ± 1.1 years), belonging to state-level soccer teams and divided by category (U-13 and U-15), were included. Players having an injury in the evaluation period were not included in the study. Measurements of body size, skeletal age (SA), motor tests, and technical actions in small-sided games (SSG) were performed (3 × 3 plus goalkeeper) in two periods (halves) of four minutes. Differences between age groups were found for SA (ES = -2.36), chronological age (ES = -3.89), body mass (ES = -2.09), height (ES = -1.90), and fat-free mass (ES = -2.09). Positive associations were found between body size (R = 0.43 to R = 0.48) and manipulation (R = 0.50 to R = 0.52) indicators and numbers of technical actions (CB and SS), except for stature with LB (R = -0.42) in the U-13 age group. In the U-15 category, skeletal age (R = -0.29 to R = -0.30) and body mass (R = -0.28 to R = -0.29) were negatively associated with the number of technical actions (RB, NB, LB, and OB) (P > 0.05) and positively with the balance with LB (R = 0.26). In conclusion, body size, SA, and motor performance influenced technical actions in SSG differentially in each category. U-13 heavier players and those with a better motor performance presented higher involvement due to the higher.

Association between cardiorrespiratory fitness and cognitive control: is somatic maturity an important mediator?

BACKGROUND: Recently some articles presented information related to the possible effect of maturity over the cognitive control and cardiorespiratory fitness, however little is known about the real effects of maturity in the relation of these variables. In this sense, the purpose of this study was to examine the potential mediating role of somatic maturity on the association between cardiorespiratory fitness (CRF) and cognitive control. METHODS: This three-year longitudinal research comprises two data collection groups: a baseline conducted in 2016 with 394 adolescents (aged 11.7 ± 0.6 years) and a follow-up in 2019 with 134 adolescents (aged 14.9 ± 0.7 years). Anthropometry data, 20-m shuttle run test and peak height velocity (PHV) to determine the maximum oxygen uptake (VO2max) and somatic maturity, respectively, were collected at both sampling times. In parallel, the Sociodemographic and cognitive control function variables were included in the follow-up to evaluate the inhibitory control (by the Stroop test) and the visuo-spatial working memory (by the Corsi block-tapping test). Associations between CRF and cognitive functions were computed by multiple linear regression, with mediation as a function of PHV. RESULTS: CRF exhibited transversal associations with reaction time in congruent (ß = -0.004; p = 0.001) and incongruent (ß = -0.005; p = 0.004) stimulus-responses. Meanwhile, the variation in VO2max over the three year-study had a significant impact on the reaction time of congruent (ß = -0.006; p = 0.001) and incongruent (ß = -0.006; p = 0.012) responses at follow-up. However, PHV did not show a significant association with the cognitive functions, indicating no mediating role. CONCLUSIONS: Although the associations between CRF and the cognitive functions exhibited great transversal and longitudinal impacts, somatic maturity did not affect the cognitive control functions, associating exclusively with CRF.

Combined effect of game position and body size on network-based centrality measures performed by young soccer players in small-sided games.

This study verified the effects of body size and game position on interactions performed by young soccer players in small-sided games (SSG). The sample consisted of 81 Brazilian soccer players (14.4 ± 1.1 years of age). Height, body mass, and trunk-cephalic height were measured. SSG was applied in the GK + 3v3 + GK format, and Social Network Analyses were carried out through filming the games to obtain the following prominence indicators: degree centrality, closeness centrality, degree prestige, and proximity prestige, in addition to network intensity and number of goals scored. Factorial ANCOVA (bone age as covariate) was used to test the effects of game position, body size, and respective interaction on centrality measurements (p < 0.05). Similarity between game positions in body size indicators (p > 0.05) was observed. The game position affected degree centrality (p = 0.01, η 2 = 0.16), closeness centrality (p = 0.01, η 2 = 0.11), and network intensity (p = 0.02, η 2 = 0.09), in which midfielders presented the highest network prominence values when compared to defenders and forwards. In conclusion, midfielders are players with high interaction patterns in the main offensive plays, which behavior is independent of body size.

Association between tracking of extracurricular sports practice and weight status during childhood: a prospective cohort study.

BACKGROUND: Overweight and obesity have reached epidemic prevalences. Obesity control involves many factors and needs to begin early in childhood. OBJECTIVES: To ascertain the association between tracked extracurricular sports practice and weight status; and to analyze tracking of overweight and obesity among school-aged children. DESIGN AND SETTING: Prospective cohort study conducted in 13 public schools in Cianorte, Paraná, in 2012-2016. METHODS: The sample comprised 2459 schoolchildren in Cianorte, of mean age 6.3 years at baseline and 9.4 years at follow-up. Body mass index was calculated from body mass and height measurements. The children were grouped as normal weight, overweight or obese. Information on extracurricular sports practice was collected through the dichotomous question "Do you participate in any extracurricular sports?" ("yes" or "no"). RESULTS: Tracking of weight status showed that 75.5% maintained this, with kappa of 0.530. Tracking of extracurricular sports practice showed that 80.9% maintained this, with low concordance (kappa of 0.054). Weight status correlation between baseline and follow-up showed that overweight or obese individuals were 4.65 times (CI: 4.05-5.34) more likely to maintain the same classification or move from overweight to obese at follow-up. Correlation of extracurricular sports practice with overweight or obesity at follow-up was not significant. CONCLUSIONS: These results demonstrated that overweight or obese children were at higher risk of gaining weight than were normal-weight children. In addition, the proportion of these children who maintained extracurricular sports practices over the years was low. Maintenance of this variable was not associated with weight status.

Relative age effect in brazilian handball selections / Efeito relativo da idade nas seleções brasileiras de handebol

ABSTRACT The aim of this study was to evaluate the relative age effect (RAE) in Brazilian male handball teams who competed in the world championships in the U-19, U-21, and adult categories. The sample was composed by 160 male handball players, 47 players being on U-19 category, 48 on U-21, and 65 on Adult category. The chronological age, body mass, height, and game position of each athlete were obtained on the International Federation of Handball website. The adopted significance level was of 5%. RAE was observed in all the three following categories U-19 (X2=21.511, P<0.01), U-21 (X2=15.894, P=0.01) and Adults (X2=35.123, P<0.01). Moreover, no RAE was found in re-selection process by sequential category (P= 0.63, U-19 to U-21; P= 0.46, U-21 to Adult). The RAE is found in Brazilian male handball national teams. However, this effect was not found in re-selection process, thus, players have great influence of RAE in U-19 and this remains through subsequent categories.

RESUMO O objetivo do presente estudo foi avaliar o efeito relativo da idade (ERI) nas seleções Brasileira de handebol que competiram nos campeonatos mundiais das categorias Sub-19, Sub-21 e Adulta. A amostra foi composta por 160 jogadores de handebol do sexo masculino, sendo 47 pertencentes a categoria Sub-19, 48 a Sub-21 e 65 a Adulta. A idade cronológica, massa corporal, estatura e posição de jogo de cada atleta foram obtidas no site oficial da Federação Internacional de Handebol. O nível de significância adotado foi de 5%. ERI foi observado em todas as três seguintes categorias Sub-19 (X2=21.511, P<0.01), Sub-21 (X2=15.894, P=0.01) e adulta (X2=35.123, P<0.01). Além disso, não foi encontrado ERI no processo de re-seleção pela categoria sequencial (P= 0.63, Sub-19 para Sub-21; P=0.46, Sub-21 para Adulta). O ERI foi encontrado nas seleções brasileiras de handebol. Contudo, este efeito não foi encontrado no processo de re-seleção, assim, os jogadores sofrem grande influência do ERI na categoria Sub-19 e isto permanece durante as categorias subsequentes até a equipe adulta.

Associations between strength, flexibility, and painful symptomology in university staff.

BACKGROUND: In the adult population, the work environment and physical fitness levels are directly related to the onset of musculoskeletal pain, repetitive strain injuries, and decreased blood circulation. Although low levels of muscle strength and flexibility may lead to a higher prevalence of pain, specific anatomic regions are poorly addressed. OBJECTIVE: To investigate the prevalence of musculoskeletal pain and the association between strength or flexibility and pain in university staff. METHODS: The sample was composed of 110 members of staff from a university in Guarapuava-PR. Body mass and height values were obtained, from which the BMI was calculated. The pain evaluation was performed by means of a questionnaire, analyzing the intensity, frequency, and anatomical region. The subjects were then submitted to strength (right and left hand grip, lumbar traction, lower limb traction) and flexibility tests (sit and reach test). RESULTS: The anatomical region with the highest prevalence of pain was the lumbar region (43.4%). When the association between the presence of pain and flexibility was performed, only the lumbar traction presented significant results, with the weakest group demonstrating pain (OR: 3.47 [1.27 - 9.49]). CONCLUSION: The results demonstrate that low levels of strength in the lumbar region are associated with the presence of painful symptomatology.

Atuação docente em Educação Física escolar na Educação de Jovens e Adultos (EJA): ações de Promoção da Saúde

RESUMO O objetivo deste estudo foi conhecer como os professores de Educação Física vem desenvolvendo suas aulas em torno da temática de Promoção da Saúde na Educação de Jovens e Adultos (EJA), uma modalidade da educação básica brasileira. A pesquisa, de caráter qualitativo, adotou como estratégia a entrevista individual com 10 professores através de curso de extensão, e utilizou como instrumento de análise de dados o Discurso do Sujeito Coletivo. Os resultados apontam que o discurso biologicista continua hegemônico nas concepções dos professores de Educação Física, possuindo um peso considerável nas reflexões de saúde e ser saudável, assim como, nas abordagens com esta temática na EJA.

ABSTRACT The aim of this study was to know how the Physical Education teachers, have been developing their classes around the theme of Health Promotion in the context of Youth and Adult Education, a form of Brazilian basic education. The research of qualitative approach, adopted as strategy ten individual interviews with teachers from the extension course, and used as a tool of analysis the technical discourse of the collective subject. The results presented point out that the biological discourse remains hegemonic in the conceptions of Health Promotion of Physical Education teachers, having a considerable weight in reflections on health and being healthy, as well as in the teaching approaches with this theme in this modality of education.

RESUMEN El objetivo de este estudio fue conocer cómo los profesores de Educación Física vienen desarrollando sus clases en torno a la temática de Promoción de la Salud en la Educación de Jóvenes y Adultos (EJA), una modalidad de la educación básica brasileña. La investigación, de carácter cualitativo, adoptó como estrategia la entrevista individual con 10 profesores a través del curso de extensión ofrecido, y utilizó la técnica del Discurso del Sujeto Colectivo como instrumento de análisis de datos. Los resultados apuntan que el discurso biologicista continúa hegemónico en las concepciones de los profesores de Educación Física, teniendo un peso considerable en las reflexiones de salud y ser sano, así como en los abordajes con esta temática en la EJA.

Which defensive tactical indicators are associated with victory in the semifinals and finals of the 2014 FIFA World Cup?

Abstract Aim: The objective of this study was to verify whether the match winners in the semifinals and finals of the FIFA World Cup 2014 were those who presented the highest frequency of pressing and intense behaviors in the recovery of ball possession. Methods: The sample was composed of 533 defensive tactical sequences performed by the four finalist teams in the 2014 FIFA World Cup. The independent t-test was used to compare tactical indicators between winning and losing teams and the chi-square test (X2) was applied to assess the association between the variables. Results: In the first (X2 = 48.47; P < 0.01) and second halves of regular matches (X2 = 64.10; P < 0.01), the evaluated teams recovered the ball in the defensive zone. However, during the first and second periods of extra time, the highest frequencies of ball recovery were found in the middle defensive zone (P < 0.01). Conclusion: It is concluded that the semi-finalist and finalist teams from the 2014 FIFA World Cup sought to recover the ball in the defensive zone, and pressing opponent movements when they were losing the matches.

Relação entre maturação esquelética e a orientação esportiva em jovens futebolistas

RESUMO O objetivo foi verificar a relação entre a orientação esportiva e a idade esquelética em atletas de futebol de 12 a 15 anos. A amostra foi de 106 jovens futebolistas, do sexo masculino, e foram feitas medidas do tamanho corporal, idade esquelética e para avaliação do comportamento competitivo usou-se o Sport Orientation Questionnaire com as subescalas competir (TQ1), vencer (TQ2) e estabelecer metas (TQ3). A Ancova não verificou diferença significativa entre os diferentes grupos de maturidade (p> 0,05) com a orientação esportiva, já a correlação de Spearman observou uma relação negativa apenas no grupo de maturidade "no tempo", com o TQ2 (r=-0,28). Conclui-se que a maturação esquelética apresentou fraca relação com o comportamento dos jovens atletas de futebol.

ABSTRACT The objective was to verify the relationship between sportsmanship and skeletal age in soccer players aged 12 to 15 years. The sample was of 106 young male soccer players, and measurements of body size, skeletal age and competitive behavior were used. The Sport Orientation Questionnaire was used with the sub scales to compete (TQ1), to win (TQ2) and to establish goals (TQ3). The ANCOVA did not find a significant difference between the different maturity groups (P> 0.05) with the sports orientation, whereas the Spearman correlation observed a negative relation only in the maturity group "in time", with TQ2 (r=- 0.28). It was concluded that the skeletal maturation presented a weak relation with the behavior of the young soccer athletes.

RESUMEN El objetivo fue comprobar la relación entre la orientación deportiva y la edad esquelética en futbolistas de 12 a 15 años. La muestra estaba compuesta por 106 jóvenes futbolistas de sexo masculino y se tomaron medidas del tamaño corporal y la edad esquelética, y para la evaluación del comportamiento competitivo se utilizó el Sport Orientation Questionnaire con las subescalas competir (TQ1), ganar (TQ2) y establecer metas (TQ3). El ANCOVA no verificó ninguna diferencia considerable entre los diferentes grupos de madurez (p> 0,05) respecto a la orientación deportiva, mientras que la correlación de Spearman observó una relación negativa solo en el grupo de madurez «en el tiempo¼ con el TQ2 (r=-0,28). Se concluye que la maduración esquelética presentó una débil relación con el comportamiento de los jóvenes futbolistas.

Tracking of nutritional status between childhood and adolescence in schoolchildren / Tracking do estado nutricional entre a infância e a adolescência em escolares / Tracking del estado nutricional entre la infancia y la adolescencia en escolares

INTRODUCTION: In view of the growing prevalence of childhood excess weight and obesity In Brazil In recent decades, it is necessary to observe how this phenomenon occurs in the period of transition to adolescence. OBJECTIVE: To verify the tracking of excess weight between childhood and adolescence in schoolchildren of both sexes. METHODS: The study has a longitudinal design and the data used are part of a prospective study carried out from 2002 to 2005. Participants included 397 schoolchildren of both sexes (211 boys and 186 girls). The nutritional status was determined by the body mass index, and the participants were divided into the following groups: Normal Weight to Normal Weight, Normal Weight to Excess Weight, Excess Weight to Excess Weight, Excess Weight to Normal Weight. The tracking was analyzed using the intraclass correlation coefficient (ICC) and Kappa (k) index. RESULTS: A significant difference (P <0.05) was observed between all variables (age and anthropometric indicators) between 2002 and 2005 for boys and girls. The ICC indicated tracking classified as high (ICC = 0.87) for the BMI values, and the tracking percentage showed that 87% of the subjects remained in the same category of normal weight and excess weight. The values of k = 0.68 show good tracking (P <0.001), indicating a strong maintenance of the subjects in the normal and excess weight categories. CONCLUSION: The tracking percentage was high, indicating that both boys and girls maintained the classification of excess weight during the period analyzed. Level of Evidence II; Lesser quality prospective study (eg, patients enrolled at different points in their disease or <80% followup).

INTRODUÇÃO: Tendo em vista a crescente prevalência de sobrepeso e obesidade na infância no Brasil nas últimas décadas, é preciso observar como esse fenômeno ocorre no período de transição para a adolescência. OBJETIVO: Verificar o tracking do excesso de peso entre a infância e a adolescência em escolares de ambos os sexos. MÉTODOS: Trata-se de estudo longitudinal e os dados utilizados fazem parte de um estudo prospectivo, realizado no período de 2002 a 2005. Participaram 397 escolares de ambos os sexos (211 meninos e 186 meninas). O estado nutricional foi determinado pelo índice de massa corporal, e os participantes foram divididos nos seguintes grupos: Peso Normal para Peso Normal, Peso Normal para Excesso de Peso, Excesso de Peso para Excesso de Peso, Excesso de Peso para Peso Normal. O tracking foi analisado pelo coeficiente de correlação intraclasse (CCI) e do índice Kappa (k). RESULTADOS: Observou-se diferença significativa (P < 0,05) entre todas as variáveis (idade e indicadores antropométricos) entre 2002 e 2005 para meninos e meninas. Com relação aos valores de IMC, o CCI indicou tracking classificado como alto (CCI = 0,87) e o percentual de tracking mostrou que 87% dos sujeitos permaneceram na mesma categoria de peso normal e excesso de peso. Os valores de k = 0,68 demonstram um bom tracking (P < 0,001), indicando uma forte manutenção dos sujeitos nas categorias de peso normal e excesso de peso. CONCLUSÃO: O percentual do tracking foi elevado, indicando que tanto meninos quanto meninas mantiveram a classificação de excesso de peso durante o período analisado. Nível de Evidência II; Estudo prospectivo de menor qualidade (por exemplo, pacientes inscritos em diferentes estágios da doença ou <80% de acompanhamento).

INTRODUCCIÓN: Teniendo en vista la creciente prevalencia de sobrepeso y obesidad en la infancia en Brasil en las últimas décadas, es preciso observar cómo ese fenómeno ocurre en el período de transición para la adolescencia. OBJETIVO: Verificar el tracking del exceso de peso entre la infancia y la adolescencia en escolares de ambos sexos. MÉTODOS: Se trata de estudio longitudinal y los datos utilizados forman parte de un estudio prospectivo, realizado en el período de 2002 a 2005. Participaron 397 escolares de ambos sexos (211 niños y 186 niñas). El estado nutricional fue determinado por el índice de masa corporal, y los participantes fueron divididos en los siguientes grupos: Peso Normal para Peso Normal, Peso Normal para Exceso de Peso, Exceso de Peso para Exceso de Peso, Exceso de Peso para Peso Normal. El tracking fue analizado por el coeficiente de correlación intraclase (CCI) y del índice Kappa (k). RESULTADOS: Se observó diferencia significativa (P < 0,05) entre todas las variables (edad e indicadores antropométricos) entre 2002 y 2005 para niños y niñas. Con relación a los valores de IMC, el CCI indicó tracking clasificado como alto (CCI = 0,87) y el porcentual de tracking mostró que 87% de los sujetos permanecieron en la misma categoría de peso normal y exceso de peso. Los valores de k = 0,68 demuestran un buen tracking (P < 0,001), indicando un fuerte mantenimiento de los sujetos en las categorías de peso normal y exceso de peso. CONCLUSIÓN: El porcentual del tracking fue elevado, indicando que tanto niños como niñas mantuvieron la clasificación de exceso de peso durante el período analizado. Nivel de Evidencia II; Estudio prospectivo de menor calidad (por ejemplo, pacientes inscritos en diferentes etapas de la enfermedad o <80% de acompañamiento).

Caracterização florística e estrutural de remanescentes florestais de Quedas do Iguaçu, Sudoeste do Paraná / Floristic and structural characterization of forest remnants in Quedas do Iguaçu, Southeastern Paraná

O sudoeste paranaense localiza-se na transição entre a Floresta Estacional Semidecidual (FES) e a Floresta Ombrófila Mista (FOM), numa região de grande relevância ecológica, por conter duas importantes formações florestais do sul-sudeste brasileiro. Entretanto, essa mesma região é marcada pela escassez de levantamentos florísticos e de caracterização da vegetação. Nesse trabalho é feita a caracterização florística e estrutural de três áreas de vegetação nativa, localizadas em Quedas do Iguaçu, sudoeste do Paraná, na bacia do rio Iguaçu. Além disso, foi feita a caracterização fitogeográfica das florestas estudadas, com base nos dados coletados e na listagem de espécies amostradas em outras 52 áreas de FES ou FOM do Brasil. Em cada uma das três áreas estudadas, a vegetação arbustivo-arbórea (diâmetro à altura do peito > 5 cm) foi caracterizada por meio da alocação de pontos quadrantes. No total foram encontradas 128 espécies, com variação entre 63 a 78 para cada área. Cada área apresentou distinção quanto à estrutura e às espécies mais abundantes. Além disso, as áreas se distinguem quanto ao grau de influência da FES e da FOM em sua composição florística. Comparativamente, a área de menor altitude, localizada no vale do Rio Iguaçu, apresenta mais elementos de FES em sua composição florística, enquanto as outras duas áreas, localizadas em trechos mais elevados, têm maior influência da FOM, contando inclusive com a ocorrência de Araucaria angustifolia (Bertol.) Kuntze.

The Southwestern region of Paraná State is an area of great ecological relevance because it represents an ecotone between two important forest types of the Brazilian south-southeastern region: the Seasonal Semideciduous Forest (SSF) and the Araucaria Forest (AF). Despite its importance, there is a lack of floristic surveys and vegetation studies in this region. In this study, we assessed floristic and structural attributes of the vegetation at three different native forest sites, located in Quedas do Iguaçu, Paraná State. Moreover, we made a phytogeografical characterization of the studied forests, based on the data we collected, and on the list of species surveyed in other 52 studies in SSF and AF of Brazil. Samples were taken using the point-centered-quarter method. All individuals with diameter at breast height > 5 cm were identified to the species level. Together, 128 species were found. Within sites, the number of species varied from 63 to 78. The three areas are distinguished with respect to structure and most abundant species. In addition, the areas differed with respect to the degree of influence of SSF and AF on their floristic composition. Comparatively, the lower altitude area, located in Iguaçu River's valley, has more elements of SSF on its floristic composition, while the other two areas, located in higher altitude areas, are more influenced by AF, with Araucaria angustifolia (Bertol.) Kuntze on their list of species.

Identificação de volume residual em seringas e agulhas após administração de medicamento por via parenteral / Identificación de volumen residual en jeringas y agujas tras administración de medicamento por vía parenteral / Identification of residual volume in syringes and needles after parenteral medication administration

A administração parenteral é realizada através de seringas, soluções e agulhas estéreis. As vias parenterais mais utilizadas são as subcutânea, intradérmica, intramuscular e intravenosa. O objetivo deste estudo é identificar o volume residual em seringas e agulhas utilizadas para administrar medicação pelas vias subcutânea, intradérmica e intramuscular. Trata-se de uma pesquisa clínica quantitativa e descritiva, realizada em 2008, no laboratório multiprofissional de um Centro Universitário do interior paulista. Foram utilizadas no estudo seringas de 1ml, 3ml e 5 ml e agulhas de 13x4,5; 20x5,5; 25x7; 25x8; 30x7 e 30x8. Durante a análise dos dados, foi possível verificar que há volume residual em seringas e agulhas, sendo o volume maior constatado de 0,07 ml, encontrado nas seringas de 5 ml, com as agulhas de 25x8 e 30x8; e de 3 ml, com a agulha 30x8. O menor volume constatado foi na seringa de 1 ml, com a agulha de 13x4,5.

Parenteral administration is performed with syringes, solutions, and sterile needles. The most commonly used parenteral routes are the subcutaneous, intradermal, intramuscular, and intravenous. This study aimed at identifying the residual volume used in syringes and needles to administer medication through the subcutaneous, intradermal, and intramuscular routes. A clinical, descriptive and quantitative research was carried out at a multiprofessional lab of a University Center in the inlands of the State of São Paulo, SP, Brazil, in 2008. Syringes of 1ml, 3ml, and 5 ml and needles of 13x4.5; 20x5.5; 25x7; 25x8; 30x7 and 30x8 were used in the study. Data analysis showed the existence of residual volume in syringes and needles. The largest volume found was 0.07 ml, in syringes of 5 ml, with needles of 25x8 and 30x8; and in 3 ml syringes with the 30x8 needle. The smallest volume was found in the 1 ml syringe, with the 13x4.5 needle.

La administración parenteral es realizada a través de jeringas, soluciones y agujas estériles. Las vías parenterales más utilizadas son las subcutánea, intradérmica, intramuscular e intravenosa. La finalidad de este estudio es identificar el volumen residual en jeringas y agujas utilizadas para administrar medicación por las vías subcutánea, intradérmica e intramuscular. Se trata de una investigación clínica, descriptiva y cuantitativa, realizada 2008, en el laboratorio multiprofesional de un Centro Universitario en el interior del estado de São Paulo, Brasil. En el estudio fueron utilizadas jeringas de 1ml, 3ml e 5 ml y agujas de 13x4,5; 20x5,5; 25x7; 25x8; 30x7 y 30x8. Durante el análisis de los datos, fue posible verificar que hay volumen residual en jeringas y agujas, siendo el mayor volumen constatado de 0,07 ml, encontrado en las jeringas de 5 ml, con las agujas de 25x8 e 30x8; y de 3 ml, con la aguja 30x8. El menor volumen constatado fue en la jeringa de 1 ml, con la aguja de 13x4,5.