Influence of collagen membrane on bone quality in titanium mesh reconstructions-Study in rats.

BACKGROUND: New bone formation and tissue remodeling are the major challenges in implantology today. Titanium meshes have demonstrated reconstructive potential for vertical bone gain. However, the soft tissue healing is technically sensitive to the surgical procedure. The combined usage of collagen membrane and specification of the meshes may ensure greater predictability. Therefore, this study aims to evaluate the influence of collagen membrane on the quality of the new bone formation in guided bone regeneration (GBR) procedures with different titanium meshes. METHODS: Twenty-eight Wistar rats were randomly allocated into four main experimental groups, according to mesh pore size in µm: Group P300 (titanium meshes, with 0.3-mm thickness and 3-mm pore size; n = 7); Group P175 (titanium meshes, with 0.3-mm thickness and 1.75-mm pore size; n = 7); Group P85: (titanium meshes, with 0.04-mm thickness and 0.85-mm pore size; n = 7); Group P15: (titanium meshes. with 0.04-mm thickness and 0.15-mm pore size; n = 7). The femurs of each animal were subdivided into test and control groups: Test: bovine bone graft associated with porcine collagen and collagen membrane was used; control: bovine bone graft associated with porcine collagen was used without association with collagen membrane. Bone quality evaluation by in vivo microtomography and histologic analysis were performed. RESULTS: Bone volume formation was similar between groups (P >0.05). However, the titanium meshes with pore size >1 mm demonstrated higher mineral bone density in comparison with meshes with pore size <1 mm (P <0.05), regardless of the combined usage of collagen membrane. All groups showed a spongy bone formation after 30 days. CONCLUSIONS: Combined usage of collagen membrane in GBR procedures with titanium mesh did not show improvements in new bone quality in rat femur model. However, titanium mesh pore size specifications may influence bone quality.

Percepção de boca seca em adultos usuários de próteses removíveis / Perception of dry mouth in adult using of removable prostheses

Objetivo: O objetivo deste estudo foi avaliar a percepção de boca seca em uma amostra de pacientes, de uma clínica de um curso de odontologia, usuários de próteses totais. Métodos: Fizeram parte do estudo 80 pacientes, que responderam a um questionário com 12 questões que caracterizavam o participante e abordava a sensação de boca seca e como a pessoa a percebia. O questionário foi pré-testado antes de sua aplicação definitiva. A análise estatística foi realizada por meio do Teste Exato de Fischer para identificar a associação da xerostomia com as variáveis independentes, com nível de significância de 5%. Resultados: Os participantes do estudo tinham, em média, 62,3 anos de idade e 55% eram do gênero feminino. Metade (50,0%) dos participantes percebiam a boca seca e 72,5% apresentavam alguma doença crônica, principalmente a hipertensão (36,1%) e a diabetes (17,1%) e estas doenças se refletiam na alta (78,8%) utilização de medicamentos de uso contínuo. Apresentavam hábitos bucais nocivos 38,8% dos participantes, principalmente o tabagismo e o bruxismo. A sensação de boca seca foi associada ao gênero, a presença de mau hálito, ao uso de medicamentos contínuos e a sensação de ardência na boca. Conclusão: A partir dos dados coletados pode-se concluir que a xerostomia foi frequente na população estudada e deve ter impacto negativo na qualidade de vida dessas pessoas. (AU)

Aim: The purpose of this study was to assess xerostomia (dry mouth) in a sample of patients who received dental care at a dentistry course clinic and who used dentures. Methods: This study included 80 patients, who answered a questionnaire with 12 questions that characterized the participant and addressed the sensation of dry mouth and how the person perceived it. The questionnaire was pre-tested before its final application. The statistical analyses were performed to identify the differences between the groups, establishing a significance level of 5% and applying the Fisher's exact test. Results: The participants of the study were, on average, 62.3 years of age, 55% of whom were female. Half (50.0%) of the participants perceived dry mouth and 72.5% had some form of chronic disease, mainly hypertension (36.1%) and diabetes (17.1%). These diseases are reflected in the high (78.8%) intake of continuous use medications. This study found that 38.8% of the participants presented harmful oral hygiene habits, mainly smoking and bruxism. The sensation of dry mouth was associated with gender, the presence of bad breath, the intake of continuous use medications, and a burning sensation in the mouth. Conclusion: From the collected data, it is possible to conclude that xerostomia (dry mouth) was frequent in the studied population, most likely causing a negative impact on these people's quality of life. (AU)