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1.
Ann Thorac Surg ; 106(6): 1759-1766, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-29966590

RESUMO

BACKGROUND: Current stratification systems for patients presenting with acute type A aortic dissection rely on signs of malperfusion to predict mortality. The authors sought to develop an algorithm to readily risk stratify these patients using admission characteristics. METHODS: Two hundred sixty-nine consecutive patients who underwent type A repair between 2002 and 2015 were reviewed for easily obtainable preoperative demographics and laboratory values deemed a priori as potential predictors of operative mortality. Multiple logistic regression analysis was performed to determine independent significance, and linear regression was performed to generate the concomitant regression expression of the variables significant on bivariate analysis. RESULTS: Operative mortality was 16% (43/269) and was 29% (34/119) among patients who presented with malperfusion. Upon multivariate analysis, creatinine (p = 0.008), liver malperfusion (p = 0.006), and lactic acid level (p = 0.0007) remained independent significant predictors. Regression coefficients allowed the generation of a risk score as 5.5 × (lactic acid [mmol/L]) + 8 × (creatinine [mg/dL]) ± 8 (+ if liver malperfusion presents, - if no liver malperfusion). Upon receiver-operating characteristic curve analysis this model generated a c-statistic of 0.75. Operative mortality among patients within the lowest tertile (risk score < 7) was 4%, whereas patients in the middle (7 to 20) and highest (≥20) tertiles had mortality rates of 14% 37%, respectively. CONCLUSIONS: Although still requiring external validation, the innovative risk score presented necessitates knowledge of lactic acid, serum creatinine, and liver function tests. The algorithm predicts operative mortality with high accuracy and offers clinicians a novel tool to improve preoperative guidance and prognosis.


Assuntos
Doenças da Aorta/cirurgia , Dissecção Aórtica/cirurgia , Complicações Pós-Operatórias/mortalidade , Doença Aguda , Adulto , Idoso , Idoso de 80 Anos ou mais , Dissecção Aórtica/classificação , Doenças da Aorta/classificação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prognóstico , Medição de Risco
2.
J Vasc Nurs ; 35(3): 146-156, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28838590

RESUMO

Surgical site infections (SSIs) have always complicated recovery after surgery, being associated with increased cost of hospitalization, length of stay, and mortality. The most significant measure to reduce the incidence of SSI was the standardization of prophylactic antibiotic administration in patients undergoing surgical procedures. Since then, countless measures have been proposed to improve rates of SSI and patient outcome, but few have been as efficacious as prophylactic antibiotics. Therefore, SSI continues to plague clinicians and patients in modern health care. This review focuses on current and future efforts at SSI control.


Assuntos
Antibioticoprofilaxia , Infecção da Ferida Cirúrgica/terapia , Procedimentos Cirúrgicos Vasculares/efeitos adversos , Virilha , Humanos , Incidência , Fatores de Risco , Infecção da Ferida Cirúrgica/etiologia , Infecção da Ferida Cirúrgica/prevenção & controle
3.
Ann Vasc Surg ; 42: 302.e15-302.e20, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28390914

RESUMO

Blunt thoracic aortic injury (BTAI) in a patient with an aberrant right subclavian artery (ARSA) presents unique challenges for patient management and aortic repair. Specific considerations include the need to treat coincidental ARSA, subclavian revascularization, and ARSA exclusion. Despite the rise of endovascular repair as the primary modality for aortic repair for BTAI, reports of this technique in the setting of ARSA are limited. Here we describe 3 patients with ARSA who underwent TEVAR for BTAI, and discuss critical management and technical issues in these patients.


Assuntos
Acidentes de Trânsito , Aneurisma/complicações , Aorta Torácica/cirurgia , Implante de Prótese Vascular , Anormalidades Cardiovasculares/complicações , Procedimentos Endovasculares , Artéria Subclávia/anormalidades , Traumatismos Torácicos/cirurgia , Lesões do Sistema Vascular/cirurgia , Ferimentos não Penetrantes/cirurgia , Adulto , Aneurisma/diagnóstico por imagem , Aorta Torácica/diagnóstico por imagem , Aorta Torácica/lesões , Aortografia/métodos , Prótese Vascular , Implante de Prótese Vascular/instrumentação , Anormalidades Cardiovasculares/diagnóstico por imagem , Angiografia por Tomografia Computadorizada , Procedimentos Endovasculares/instrumentação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Desenho de Prótese , Artéria Subclávia/diagnóstico por imagem , Traumatismos Torácicos/diagnóstico por imagem , Traumatismos Torácicos/etiologia , Resultado do Tratamento , Lesões do Sistema Vascular/diagnóstico por imagem , Lesões do Sistema Vascular/etiologia , Ferimentos não Penetrantes/diagnóstico por imagem , Ferimentos não Penetrantes/etiologia
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