RESUMO
Ancient DNA shows continuity between living and ancient Maya communities.
Assuntos
Comportamento Ritualístico , Civilização , DNA Antigo , Gêmeos , Feminino , Humanos , Masculino , História Antiga , Gêmeos/história , Criança , Civilização/históriaRESUMO
Complex tools from 300,000-year-old deposit at Schöningen in Germany point to a "wood age".
Assuntos
Homem de Neandertal , Madeira , Animais , Arqueologia , Alemanha , Homem de Neandertal/psicologiaRESUMO
Moderns made mysterious ice age artifacts-implying overlap with Neanderthals.
Assuntos
Homem de Neandertal , Animais , Humanos , Europa (Continente) , FósseisRESUMO
Among Europeans, risk of multiple sclerosis rises with genes from Bronze Age Yamnaya herders.
Assuntos
DNA Antigo , Esclerose Múltipla , Humanos , Europa (Continente)/epidemiologia , Genoma Humano , Esclerose Múltipla/epidemiologia , Esclerose Múltipla/genética , Esclerose Múltipla/históriaRESUMO
8000 years ago-long before farming arrived-people in Siberia built defensive structures.
Assuntos
Caça , Humanos , Fazendas/história , Sibéria , Caça/históriaRESUMO
Despite more than 80 years of use in a number of conditions, including in critically ill patients, comments have recently arisen regarding the safety and efficacy of human serum albumin (HSA) as a therapeutic product and stabilizer/excipient in botulinum neurotoxins. This review summarizes the literature on the safety of HSA. Beyond decades of safe use, the largest clinical dataset of HSA safety is a large meta-analysis of HSA supplier data, which found only an extremely remote risk of serious adverse events across millions of doses of therapeutic concentrations of HSA. There is a paucity of literature identifying HSA-specific adverse events when used as a stabilizer/excipient; however, studies of HSA-containing botulinum neurotoxins (BoNTs) suggest that adverse events are not related to HSA. Polysorbates, which are synthetically produced and not physiologically inert, are contained in pending or new-to-market BoNT formulations. In contrast to HSA, evidence exists to suggest that polysorbates (particularly PS20/PS80) can cause serious adverse events (e.g., hypersensitivity, anaphylaxis, and immunogenicity).
Assuntos
Toxinas Botulínicas Tipo A , Toxinas Botulínicas , Humanos , Toxinas Botulínicas/efeitos adversos , Albumina Sérica Humana/efeitos adversos , Excipientes , Polissorbatos , Toxinas Botulínicas Tipo A/efeitos adversosRESUMO
Giant family trees based on ancient DNA from thousands of people are revealing prehistoric politics and social structure.
RESUMO
DNA from enslaved Black workers at a 19th century iron forge links them to living descendants. But the research swirls with ethical questions.
RESUMO
Genes reveal striking diversity within similar ice age cultures.
Assuntos
Diversidade Cultural , DNA Antigo , Europa (Continente) , HumanosRESUMO
After the Spanish conquest, horses transformed Native American tribes much earlier than historians thought.
Assuntos
Indígena Americano ou Nativo do Alasca , Cavalos , Interação Humano-Animal , Animais , América do Norte , Espanha , Arqueologia , HumanosRESUMO
Ancient DNA reflects foreign influx to Swahili coast, but its culture is largely local.
RESUMO
Analysis reveals the chemicals applied to corpses in a 2700-year-old mummification workshop.
Assuntos
Múmias , Humanos , Cadáver , Egito , História Antiga , Múmias/históriaRESUMO
Meat from the butchered beasts would have fed hundreds.
Assuntos
Comportamento Alimentar , Processos Grupais , Caça , Carne , Homem de Neandertal , Animais , Ingestão de Alimentos , Carne/história , Homem de Neandertal/psicologia , Caça/história , ElefantesRESUMO
DNA from a medieval German cemetery opens a window on the history of today's largest Jewish population.
Assuntos
Judeus , Judeus/genética , População/genética , Alemanha , Cemitérios/história , DNA Antigo , HumanosRESUMO
By sequencing ancient hominins' DNA, Pääbo explored "what makes us uniquely human".
Assuntos
DNA Antigo , Hominidae , Animais , Hominidae/genética , Humanos , Prêmio NobelRESUMO
Genetic study of burials suggests whole families migrated to the island in the first millennium C.E.
Assuntos
Emigração e Imigração , População Branca , Sepultamento , DNA Antigo , Emigração e Imigração/história , Inglaterra , História Antiga , Humanos , Análise de Sequência de DNA , População Branca/genéticaRESUMO
Studies seek clues to origins of farming, early languages.
Assuntos
Civilização , DNA Antigo , Fazendas , Idioma , Civilização/história , Fazendas/história , História Antiga , Humanos , Idioma/história , Oriente MédioRESUMO
Russian disinformation campaign targets routine research on bat parasites.
RESUMO
Researchers hide ancient weapons and bat skulls, upload data as bombs fall.