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1.
J Investig Med High Impact Case Rep ; 11: 23247096221150635, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36738077

RESUMO

Neuroretinitis is a condition typically characterized by unilateral optic neuropathy and is most commonly a sequelae of cat scratch disease (CSD) due to infection with Bartonella henselae. Ophthalmologic examination will reveal a swollen optic nerve and may eventually reveal a canonical macular star; optical coherence tomography (OCT) will reveal flattening of the fovea, a thickened neurosensory retina, and subretinal fluid accumulation. Although CSD rarely presents with isolated neuorretinitis, it should be considered in patients presenting with unilateral visual changes. The differential diagnosis for neuroretinitis includes optic neuritis, inflammatory optic neuropathies (sarcoid, para-infectious, autoimmune), compressive, toxic, and more. We describe a pediatric patient presenting with visual changes that were initially concerning for optic neuritis and the diagnostic workup that ultimately led to a diagnosis of CSD neuroretinitis.


Assuntos
Bartonella henselae , Doença da Arranhadura de Gato , Coriorretinite , Neurite Óptica , Retinite , Humanos , Doença da Arranhadura de Gato/complicações , Doença da Arranhadura de Gato/diagnóstico , Retinite/diagnóstico , Retinite/complicações , Neurite Óptica/diagnóstico , Neurite Óptica/etiologia
3.
J Investig Med High Impact Case Rep ; 7: 2324709619838309, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31010318

RESUMO

Tolosa-Hunt syndrome is characterized by a painful ophthalmoplegia secondary to a granulomatous inflammation in or adjacent to the cavernous sinus. Magnetic resonance imaging will show enhancement of the cavernous sinus and/or the orbital apex. Although this syndrome is extremely rare in children, it should be a diagnostic consideration in patients presenting with painful ophthalmoplegia with variable involvement of cranial nerves II to VI. The differential diagnosis for unilateral cavernous sinus lesion is broad, including vascular lesions (cavernous sinus thrombosis), inflammatory processes (sarcoidosis, autoimmune), neoplastic processes (schwannoma, lymphoma), as well as infectious etiologies. We describe a pediatric patient presenting with neurological symptoms from a unilateral cavernous sinus magnetic resonance imaging abnormality and the thorough diagnostic approach to arrive at the diagnosis of Tolosa-Hunt syndrome.


Assuntos
Seio Cavernoso/patologia , Diplopia/etiologia , Cefaleia/etiologia , Síndrome de Tolosa-Hunt/diagnóstico , Adolescente , Diagnóstico Diferencial , Feminino , Glucocorticoides/uso terapêutico , Humanos , Aumento da Imagem , Imageamento por Ressonância Magnética , Síndrome de Tolosa-Hunt/tratamento farmacológico
4.
J Investig Med ; 67(2): 346-349, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30287476

RESUMO

Child maltreatment remains a significant problem in the USA. There is a dearth of literature examining the association of socioeconomic status (SES) and incidence of child maltreatment among hospitalized children across the entire USA. Our aim was to study the association between SES and incidence and mortality from child maltreatment among hospitalized children in the USA. We used 2013-2014 data from the Nationwide Inpatient Sample, a discharge database representative of all hospitals in the USA. International Classification of Diseases-9 codes for general child maltreatment were used to identify patients discharged with a primary diagnosis of child maltreatment. Trends in the incidence and outcomes of child maltreatment were compared with SES based on quartiles (Qx) of median household income. In 2013-2014, there were a total of about 2.3 million pediatric discharges. Out of these, a total of 8985 had a primary diagnosis of child maltreatment. Approximately 40 per cent of the cases were from families with the lowest SES (Q1). In-hospital mortality was 2.4 per cent in Q1 (lowest SES) compared with 0.4 per cent in Q4 (highest SES). We conclude that children from lower SES households have a higher incidence of child maltreatment and have worse outcomes, including significantly higher in-hospital mortality among hospitalized children. This trend was generally consistent across all age groups and ethnicities. To our knowledge, this is the first report studying the association between SES and children with child maltreatment among hospitalized children across the entire USA.


Assuntos
Maus-Tratos Infantis/estatística & dados numéricos , Hospitalização/estatística & dados numéricos , Classe Social , Criança , Etnicidade , Características da Família , Feminino , Mortalidade Hospitalar , Humanos , Incidência , Renda , Masculino , Fatores de Risco , Estados Unidos/epidemiologia
7.
J Investig Med High Impact Case Rep ; 5(3): 2324709617727759, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28959692

RESUMO

Bullous skin lesions are uncommon in children. While it is well known that Mycoplasma infections are associated with papular skin manifestations, bullous skin lesions are not commonly reported. Mycoplasma pneumoniae is a very common bacterial pathogen causing respiratory tract infection in children and adults. We report 2 children with serology-confirmed Mycoplasma infection who were hospitalized for blistering skin lesions. Both of our patients responded well to corticosteroids and one of them required intravenous immunoglobulin. The aim of this case report is to raise awareness that Mycoplasma pneumoniae infection can present with bullous skin lesions, and to briefly review the pathophysiology, diagnosis, and management of the skin manifestation of Mycoplasma infection.

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