[Short- and long-term benefits of smoking cessation]. / Bénéfices à court et à long termes de l'arrêt de la consommation de tabac.

The beneficial effects of withdrawal smoking on the disrupted physiological functions bound to tobacco spread differently: some weeks for smell, taste and breathing, to the less six months to recover tolerance to the effort without dyspnea. For the cardiac attack the risk bound to tobacco disappears after five years, and the risk for cancers after ten years. The expectation of life of the ex-smoker joined the one of non-smokers 15 years after the stop of smoking. The tobacco use by the women raise some particular problems. To convince the smoker to persevere in the decision of withdrawal smoking and to be free of dependences (pharmacological and psychological) it could be necessary to use the nicotinic substitutes and/or a psychological support. Stop smoking is the better and the most economic therapeutic to avoid recurrence of cardiac attack for a lot of authors.

Tetanie latente: action d'une eau minerale naturelle magnesienne (hydroxydase) / Tetany: action of natural magnesian mineral water (hydroxydase)

Chez un groupe de 10 sujets dont la tetanie latente a ete verifiee par une echelle specifique validee, appelee echelle de spasmophilie, un traitement par deux cures d'eau d'Hydroxydase a ete mis en place. Cette... (AU)

Kinetics of plasma coagulation and lysis I: Basic kinetic model for time course of coagulation-lysis systems and its potential application to clinical studies.

The time courses of coagulation and coagulation-lysis were spectrophotometrically monitored after the addition of thrombin or thrombin-streptokinase to plasma, diluted 1:5 with normal saline, obtained from normal and presumably abnormal subjects. The kinetics of clotting, after an initial lag period of 0.5-1.5 min, demonstrated essentially first-order dependence on the amount of fibrinogen available to form the clot, and the asymptotic absorbance was independent of thrombin concentration. The rate of clotting was a function of added thrombin, and the ratios of the rate constants at 2.5 and 1.25 units of thrombin/ml of undiluted plasma were 1.65 +/- 0.03 SEM. At early times, the coagulation-lysis curve with thrombin-streptokinase could be superimposed on the clotting curve with thrombin alone for a given plasma with minor compensation for variable lag times. Subsequently, the curves diverged; lysis was monitored by the decrease in absorbance of the coagulation-lysis system. The rate of fibrinolysis increased with streptokinase concentration and was a function of the extent of lysis, and it permitted the description of the kinetics of lysis by a pseudoautocatalytic mechanism where the bimolecular rate constant appears proportional to streptokinase concentration. Ranges of clotting and lytic parameters for the plasma of normal subjects are given, and their potential use in diagnosing abnormalities is described.