[Liver capillariasis (Calodium hepaticum) in rodents from Ituri (DRC) and Dakar (Senegal)]. / Capillariose hépatique (Calodium hepaticum) chez des rongeurs en Ituri (République démocratique du Congo) et à Dakar (Sénégal).

Human hepatic capillariosis due to Calodium hepaticum is rarely described in Africa, probably because of the lack of diagnosis tools. However, it is known that the animal reservoir is made up of rodents. During a study performed on 24 black rats (Rattus rattus) trapped in Rethy (CongoDR) and 20 Gambian pouched rats (Cricetomys gambianus) in Dakar (Senegal), macroscopic and histological hepatic lesions of capillariosis were found in 8 of these rodents (3 in Rethy and 5 in Dakar). These results led us to propose, besides hygiene measures, an epidemiologic survey of this serious parasitosis, particularly in children, in the course of serological and/or coproscopic investigations.

Prevalence of Capillaria hepatica in non-commensal rodents from a forest area near Dijon, France.

Capillaria hepatica is a zoonotic parasite (nematode) found in the liver of many mammals, especially rodents, worldwide. In this study, 94 non-commensal rodents were trapped in a forest area near Dijon, France, including 65 Apodemus spp. and 29 Myodes glareolus. Pathology was studied on the liver of each rodent. Histological lesions consisting of chronic multifocal granulomatous hepatitis due to both eggs and adult forms of the parasite were observed in the liver of eight M. glareolus and one Apodemus spp. The global prevalence of 9.6 % was significantly higher in M. glareolus (27.6 %) compared to Apodemus spp. (1.5 %) living in the same ecosystem. No significant difference in the infection rate was found between males and females of M. glareolus. Gross pathological lesions compatible with capillariasis were observed in four of nine rodents. These results raise the role of wild rodents in the maintenance of capillariasis in nature, and their possible role in the transmission to humans.

Nasal cavity lobular capillary hemangioma due to insect sting.

INTRODUCTION: Lobular capillary hemangioma is a frequent benign vascular inflammatory lesion of the skin tissue. It rarely reaches the mucous membrane, and the nasal fossa involvement is exceptional. CASE REPORT: A 68-year-old woman presented with an ulcerous hemorrhagic mass blocking the left nasal fossa, which had appeared a few weeks after a wasp sting in the nose. The insect was evacuated only three weeks after the sting. The clinical and radiological data suggested malignancy. Biopsy under local anesthesia proved non-contributory and was complicated by 1 week's hospitalization for severe nosebleed. Surgical excision under video-endoscopy confirmed diagnosis. At 31 months' follow-up, the patient was free of recurrence. DISCUSSION/CONCLUSION: The pathogeny of lobular capillary hemangioma is uncertain. No previous cases affecting the mucous membrane after insect sting have been reported. Except in the typical contexts of long-term packing or pregnancy, diagnosis can be difficult and misleading. It can mimic a malignant pathology. Its rich vascularization requires caution during biopsy, and the risk of recurrence requires excision to be complete.

Adenocarcinoma of the upper esophagus.

Glandular heterotopia of the upper esophagus is a congenital abnormality that is frequently discovered during upper digestive tract endoscopy (in 0.26-4.9% of cases), but usually with no malignant potential. Indeed, adenocarcinoma of the upper esophagus related to such lesions is a rare entity. We report here the 27th observation of this rare type of tumor in an 87-year-old man complaining of cervical dysphagia. This adenocarcinoma had developed from an area of gastric heterotopia 3 cm below the upper sphincter of the esophagus. The treatment regimen was based on exclusive radiochemotherapy, which led to a complete endoscopic response at the end of treatment. The patient's symptom-free survival was six months and overall survival was 17 months from diagnosis. This case of a rare tumor of the upper esophagus raises the question of whether the detection and surveillance of this type of heterotopia would be useful and, thus, to be recommended.

[Sporotrichoid topographic distribution and Mycobacterium marinum grown on a subdermal contraceptive implant]. / Dissémination lymphangitique et greffe sur implant contraceptif de Mycobacterium marinum.

We report a 37-year-old woman who presented a cutaneous papulonodular skin eruption with sporotrichoid topographic distribution. The diagnosis of Mycobacterium marinum infection was obtained with the bacteriological examination of a cutaneous biopsy and related to cleaning her aquarium at home. Mycobacteriological grown on a subdermal contraceptive implant had not been published before.

[Bilateral pulmonary nodules in an HIV-infected patient]. / Nodules pulmonaires bilatéraux chez un patient infecté par le VIH.

INTRODUCTION: Although infectious causes are the most common source of pulmonary nodules in HIV-infected patients, malignant diseases such as Kaposi sarcoma and lymphoma must also be considered. OBSERVATION: A 40 year-old man, diagnosed with HIV infection 16 years earlier and with a satisfactory viro-immunological control, was hospitalized for bilateral pulmonary nodules and a dorsal lytic mass. Bone and pleural biopsies showed a malignant epithelioid hemangioendothelioma. COMMENT: Epithelioid hemangioendothelioma is an uncommon low grade vascular tumor. We report the first case in an HIV-infected patient. Bilateral pulmonary nodules are common in this malignant disease but are not specific. In a HIV-infected patient, such clinical presentation is associated with numerous differential diagnoses and must be interpreted in relation to the immune status. CONCLUSION: In HIV-patients without immunosuppression, pulmonary nodules are often malignant. With the increased survival of these patients, these etiologies closer to those of non-infected patients.

White matter changes and ventricular enlargement on magnetic resonance imaging: Comparison between normal elderly subjects and patients with cerebrovascular disorders.

T2-weighted magnetic resonance imaging has been shown to be effective in detecting changes in cerebral white matter. High signal intensity in cerebral white matter regions has been suggested to be indicative of the presence of a disease state. In normal aging, white matter changes, known as leuko-araiosis, have been reported to be widespread. Some studies have linked leuko-araiosis to aging and risk factors for stroke. There is also evidence that changes in cerebral white matter occur in hydrocephalus and that enlargement of the lateral ventricles is a byproduct of severe white matter changes. This study reports data on the frequency and severity of leuko-araiosis in normal subjects and patients with cerebrovascular disease and explores the relationship between white matter changes and ventricular dilatation.