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Eur J Appl Physiol ; 111(7): 1517-27, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21190035

RESUMO

VO2, Q and muscular deoxyhaemoglobin (HHb) kinetics were determined in 14 healthy male subjects at the onset of constant-load cycling exercise performed at 80% of the ventilatory threshold (80%(VT)) and at 120% of VO2max (120%(Wmax)). An innovative approach was applied to calculate the time constant (τ2) of the primary phase of VO2 and Q kinetics at 120%(Wmax). Data were linearly interpolated after a semilogarithmic transformation of the difference between required/steady state and measured values. Furthermore, VO2, Q and HHb data were fitted with traditional exponential models. τ2 of VO2 kinetics was longer (62.5 ± 20.9 s) at 120%(Wmax) than at 80%(VT) (27.8 ± 10.4 s). The τ2 of Q kinetics was unaffected by exercise intensity and, at 120% of VO2max, it was significantly faster (τ2 = 35.7 ± 28.4 s) than that of VO2 response. The time delay of HHb kinetics was shorter (4.3 ± 1.7 s) at 120%(Wmax) than at 80%(VT) (8.5 ± 2.6 s) suggesting a larger mismatch between O2 uptake and delivery at 120%(Wmax). These results suggest that VO2 at the onset of exercise is not regulated/limited by muscle's O2 utilisation and that a slower adaptation of capillary perfusion may cause the deceleration of VO2 kinetics observed during supramaximal exercise.


Assuntos
Débito Cardíaco/fisiologia , Exercício Físico/fisiologia , Músculo Esquelético/metabolismo , Consumo de Oxigênio/fisiologia , Oxigênio/metabolismo , Adaptação Fisiológica/fisiologia , Adulto , Teste de Esforço , Hemoglobinas/metabolismo , Humanos , Cinética , Masculino , Músculo Esquelético/fisiologia , Esforço Físico/fisiologia , Troca Gasosa Pulmonar/fisiologia , Adulto Jovem
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